Is Natural Factors PEA400 worth it?

It is a reasonable pick if you want 400 mg micronized PEA in a vegan capsule at a competitive price. PEA evidence is promising but not definitive, so judge it over several weeks rather than days.

How many capsules should I take?

The label says 1 capsule one to three times daily, and also lists a recommended adult dose of 3 capsules once daily. Follow your health care provider's guidance, since the label is inconsistent.

How long does one bottle last?

The bottle has 90 capsules. At one capsule daily it lasts about three months; at three capsules daily it lasts about 30 days.

Is it vegan and gluten-free?

Yes. It uses a vegetarian capsule, is gluten-free, and is third-party certified non-GMO. The PEA comes from safflower oil.

How does it compare with other PEA supplements?

The key differences are dose per capsule and micronization. PEA400 gives 400 mg per capsule in micronized form, so compare cost per 400 mg against rivals rather than bottle price alone.

When is the price lowest?

At $34.99 at Fruitful Yield as of November 4, 2026, it is at the low end of the six stores listing it. Watch for multi-bottle discounts, since long-term use runs through bottles quickly.

Where is the Natural Factors PEA400 cheapest?

At Fruitful Yield, for $34.99, as of our latest check.

Where can I buy the Natural Factors PEA400?

6 stores we checked sell it, including Walmart, Fruitful Yield, eBay, Community Natural Foods, Target.

Natural Factors PEA400

Q: What do buyers say about the Natural Factors PEA400?

Rated 4.7 out of 5 from 221 ratings.

4.7

Best price now

$34.99at Fruitful YieldObserved at 12:34 AM

Compared across 6 stores. Prices are checked against each store and labelled with when.

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Our take on the Natural Factors PEA400

Natural Factors PEA400 is a vegetarian capsule supplement supplying 400 mg of palmitoylethanolamide (PEA) per capsule, made from fractionated non-GMO safflower oil and micronized for better solubility. It is marketed for occasional and nerve-related pain and discomfort, with a suggested dose of 1 capsule one to three times daily. The bottle holds 90 capsules, so a three-capsule daily routine lasts about a month. At $34.99 at Fruitful Yield as of November 4, 2026, it sits at the low end of what the six stores listing it charge.

Best forAdults exploring PEA for nerve-related discomfort such as sciatica or carpal tun

What reviewers say

Rated 4.7 out of 5 from 221 ratings, buyers generally report the capsules are easy to take and well tolerated, with some noticing less discomfort over weeks of use. Others say they felt no difference, which fits the mixed evidence for PEA.

Pros

Easy-to-swallow vegetarian capsules
No noticeable side effects for most users
Perceived relief for nerve and joint discomfort with continued use
Clean label: vegan, gluten-free and non-GMO

Cons

No effect for some users
Relief, when reported, tends to take weeks
Dose needed can mean finishing a bottle quickly
Price per bottle adds up for long-term use

About the Natural Factors PEA400

Natural Factors PEA400 - A chronic pain relief formula made from fractionated non-GMO safflower seed oil. Palmitoylethanolamide (PEA) is a fatty-acid-like compound found naturally in certain foods and made within the body. Micronization improves PEA’s solubility and absorption to help manage a variety of conditions associated with chronic pain and discomfort. PEA has analgesic, neuroprotective, and anti-neuroinflammatory properties. It activates the endocannabinoid system and has been used successfully for conditions associated with chronic pain and discomfort. It has been studied for nerve compression syndromes, including sciatica and carpal tunnel syndrome, and for pain caused by pinched nerves and temporomandibular joint (TMJ) disorders.

Ingredients:

Each vegetarian capsule contains:

Palmitoylethanolamide (safflower oil) (seed) 400 mg

PEA (palmitoylethanolamide) is a fatty-acid-like compound naturally found in foods. Natural Factors PEA is naturally produced from fractionated non-GMO safflower oil. It then undergoes a micronization process for improved solubility and absorption. PEA has been shown to be helpful in managing chronic pain and discomfort.

Non-Medical Ingredients:

Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica, stearic acid.

Dosage:

Recommended adult dose:

3 capsules once daily or as directed by a health care practitioner.

For use beyond 4 months, consult a health care practitioner.

Caution:

Consult a health care practitioner if symptoms persist or worsen. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Keep out of the reach of children.

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.