Which is better for long work calls?

The Sony WH-CH720N. Its beamforming mic, Precise Voice Pickup and wind noise reduction give clearer speech, and at 192 g it is easier to wear for hours.

Which has better noise cancelling?

Close. The Space One claims up to 98% reduction in Soundcore lab tests and owners rate it well. The Sony uses Dual Noise Sensor tech with the V1 processor. Try both if you fly often.

Which lasts longer on a charge?

The Space One. It runs 40 hours with ANC on and 55 hours off, against up to 35 hours for the Sony.

Is the Sony worth stepping up to?

Step up if weight and call clarity matter most. Otherwise the Space One gives you more battery, LDAC and multipoint for less.

Which sounds better for bass?

The Space One. Owners describe it as clear and bass-rich. The Sony is tuned flatter and favors vocals.

Can I connect two devices at once?

Only on the Space One, which supports multipoint over Bluetooth 5.3. The Sony pairs with one device at a time.

Anker Soundcore Space One vs Sony WH-CH720N

The Sony WH-CH720N is the lighter, more balanced headphone and the better pick for long calls and all-day wear. The Soundcore Space One counters with longer battery life, LDAC hi-res audio and a fuller bass sound. Owners of both praise comfort and noise cancelling; the Space One gets more consistent praise for bass and multipoint, while the Sony wins on weight and vocal clarity.

Choose the Soundcore Space One if you want the longest battery life, LDAC hi-res audio and punchy bass, and you often pair two devices at once.
Choose the Sony WH-CH720N if you want the lightest over-ear of the two, a balanced sound for vocals and podcasts, and clear calls.

Prices

Anker Soundcore Space One: $59.04 at Mercari (last seen Nov 5)
Sony WH-CH720N: $50.98 at Reebelo USA (checked today)
Difference: the Sony WH-CH720N is $8.06 cheaper than the Anker Soundcore Space One at the latest prices (Nov 5 and Nov 10)