Which is better for long runs?

The GEL-Nimbus 26 Wide. Its maximum cushioning and taller stack protect the legs over distance better than the Ghost's balanced setup.

Which is better for daily training and tempo runs?

The Ghost 16 Wide. It is lighter and firmer, so it feels more responsive when you pick up the pace.

Both hold up well for neutral road shoes. The Nimbus has more foam and a grippier outsole, but its extra weight and soft foam can pack down sooner for heavy runners.

Is the Nimbus worth stepping up to?

If you want maximum cushioning and plush comfort for long or easy miles, yes. If you want one versatile shoe for all runs, the Ghost covers more ground.

Which suits high arches and wide feet?

Both come in wide widths. The Ghost lists medium and high arch support with a 12 mm drop; the Nimbus is neutral with an 8 mm drop and a knit upper that stretches a little.

Brooks Ghost 16 Wide vs ASICS GEL-Nimbus 26 Wide

The Ghost 16 Wide is the better pick for most runners who want a light, balanced daily trainer with a roomy wide fit. The GEL-Nimbus 26 Wide is the step up for runners who want maximum cushioning and a softer, more plush ride, at the cost of about an ounce of extra weight. Both are neutral shoes with wide options; reviewers consistently praise the Ghost for all-around versatility and the Nimbus for long-run comfort.

Choose the Ghost 16 Wide if you want a lighter, balanced daily trainer for everyday miles and a firmer, more responsive feel.
Choose the GEL-Nimbus 26 Wide if you want maximum cushioning and a plush, protective ride for long or easy runs.

Prices

Brooks Ghost 16 Wide: $98.00 at Amazon (checked today)
ASICS GEL-Nimbus 26 Wide: $75.95 at Amazon (checked today)
Difference: the ASICS GEL-Nimbus 26 Wide is $22.05 cheaper than the Brooks Ghost 16 Wide today