Brooks Glycerin 22 vs Brooks Women's Glycerin 22 SE
Both are Glycerin 22 shoes with neutral support, a 10mm drop and maximum cushioning. The men's Glycerin 22 is the better pick for most runners: it comes in a wide width, has a rubber outsole for road and cross-training use, and costs $99.95 at Amazon as of November 4, 2026. The Women's Glycerin 22 SE is $79.95 at Amazon as of November 4, 2026, and suits women who want a laceless slip-on with a flat knit upper.
Today the Brooks Women's Glycerin 22 SE costs $20.00 less at its best price.
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Brooks Glycerin 22
Choose the Glycerin 22 if you need a wide width, a lace closure you can adjust, or one shoe for running and cross-training.
- Wide width available for broader feet
- Single-pull lace lets you adjust fit quickly
- Rubber outsole works for running and cross-training
- Stack height of 38.5mm heel and 28.5mm forefoot gives plush cushioning
What separates them
| Brooks Glycerin 22 | Brooks Women's Glycerin 22 SE | |
|---|---|---|
| Price (as of November 4, 2026) | $99.95 at Amazon | $79.95 at Amazon |
| Width options | Wide width listed | Standard women's fit only |
| Closure | Single-pull lace | Laceless |
| Upper | Synthetic | Flat knit nylon |
| Cushioning | DNA Loft v3-style max cushion, 38.5mm heel / 28.5mm forefoot | Nitrogen-infused DNA Tuned, maximum cushioning |
| Weight | 10.2 oz (289g) | Not listed |
| Use case | Running and cross-training | Road and treadmill |
| Care | Wipe or machine wash per label |
Price history
- Brooks Glycerin 22: lowest $84.95 on Nov 2 at Amazon; $99.95 on Nov 4.
- Brooks Women's Glycerin 22 SE: lowest $79.95 on Nov 4 at Amazon.
Prices at every store
Brooks Glycerin 22
- AmazonNew
Availability unknown
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$99.95Free shippingObserved at 10:13 AM
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Brooks Women's Glycerin 22 SE
- AmazonNew
Availability unknown
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$79.95Free shippingObserved at 10:13 AM
Specs compared
| Spec | Brooks Glycerin 22 | Brooks Women's Glycerin 22 SE |
|---|---|---|
| Heel-to-toe drop | 10mm | 10mm |
| Shoe size | 8.5 | — |
| Brand | Brooks | — |
| Athletic shoe type | Cross-Training Shoes | — |
| Color | Black | — |
| Shoe category | Men's Shoes | — |
| Shoe width | Wide | — |
| Shoe closure | Single-Pull Lace | — |
| Footwear feature | Diabetic | — |
| Foot pronation | Neutral Pronation | — |
| Sport |
What reviewers say
Brooks Glycerin 22
The Glycerin line is generally well regarded for plush cushioning and a smooth ride, and the 22 continues that reputation. Owners often note the comfort over long distances, while some find the shoe heavy and the toe box snug.
- Soft, well-cushioned ride for long runs
- Comfortable straight out of the box
- Durable rubber outsole
- Heavier than many daily trainers
- Toe box can feel tight
- Less responsive than firmer shoes
Brooks Women's Glycerin 22 SE
Owners of the Glycerin line generally praise the soft, protective ride and the roomy knit upper. The laceless SE version draws mixed feedback: some love the easy on-off fit, while others find it less secure than laced Glycerins for anything beyond easy pace.
- Very soft, protective cushioning for long easy runs
Questions and answers
- Which is better for wide feet?
- The men's Glycerin 22. It is listed in a wide width, while the Women's Glycerin 22 SE comes in a standard women's fit only.
- Is the Women's Glycerin 22 SE worth the savings?
- At $79.95 versus $99.95 at Amazon as of November 4, 2026, the SE saves about $20 and adds a laceless knit upper. If you need a wide width or an adjustable lace, pay the extra for the Glycerin 22.
- Which lasts longer?
- Both use a rubber outsole and a neutral max-cushion midsole, so wear should be similar. The Glycerin 22's lace closure is easier to replace or retie than a laceless knit upper.
- Can I run in the Women's Glycerin 22 SE?
- Yes. It is built for road and treadmill running with a 10mm drop and maximum cushioning. It is not water resistant, so avoid wet trails.
- Which is better for cross-training?
- The Glycerin 22. It is listed for running and cross-training, while the SE is recommended for road and treadmill only.
- Do both have the same drop?
- Yes. Both list a 10mm heel-to-toe drop and neutral pronation support.