Which is better for long typing sessions?

The Q10. Its Alice layout angles the key columns so your wrists sit straighter, and buyers specifically cite less wrist and elbow strain. The Q2 is a straight board with a fixed medium incline.

Is the Q10 worth it over the Q2?

It is cheaper at the latest prices, $71.99 versus $79.99 as of October 28, and adds ergonomic shaping plus macro keys. The Q2 gives you a smaller footprint, a 1000 Hz polling rate and a much larger review base.

Which has the better build quality?

Both use full CNC 6063 aluminum cases with gasket mounting and hot-swap sockets, so build quality is close. The Q2's 4.5 rating from 308 ratings is stronger evidence over time than the Q10's 4.3 from 50.

Can I change the switches on either one?

Yes. Both are hot-swappable and accept 3-pin and 5-pin MX-style switches, so you can swap in different Gateron or third-party switches without soldering.

Which is better for gaming?

The Q2. It lists a 1000 Hz polling rate and its compact 65% size leaves more room for mouse movement. The Q10's Alice layout is aimed at typing comfort, not fast mouse play.

Do both work with a Mac?

Both ship with Mac and Windows keycaps and run QMK. The Q10's listing explicitly names macOS support; the Q2's listed compatibility field says Windows, so check the Mac keycap set and remap in QMK.

Keychron Q2 Knob 65% Mechanical Keyboard vs Keychron Q10 QMK Keyboard

Buy the Q2 if you want a compact 65% board with a right-side knob and a proven track record of 308 ratings at 4.5 stars. Buy the Q10 if wrist comfort matters more than desk space and you want an Alice layout with left-side macro keys. The Q10 is the cheaper board right now: $71.99 as of October 28, versus $79.99 for the Q2 as of October 28. Both are wired, aluminum, hot-swappable QMK boards, so the choice comes down to layout and ergonomics, not build quality.

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