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La Roche-Posay Effaclar Serum vs Olay Regenerist Collagen Peptide 24 Serum

Buy the La Roche-Posay Effaclar Serum if your main problem is clogged pores, blackheads and post-acne marks. Buy the Olay Regenerist Collagen Peptide 24 if you want a gentle daily hydrating serum for plumpness and fine lines. The Effaclar is $34.98 at Shop Simon as of November 8, 2026, and has sold as low as $19.00 on November 2, 2026. No current price was given for the Olay, so compare it against the Effaclar's $34.98 before deciding.

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La Roche-Posay
La Roche-Posay Effaclar Serum

La Roche-Posay Effaclar Serum

4.8(28,000 ratings)
$33.99at TargetObserved Nov 7, 2026, 10:52 AM
See all prices and details
Visit Target

Store links may earn us a commission. Price via Klarna.

Choose the Effaclar Serum if you have oily or acne-prone skin and want salicylic acid plus glycolic acid to unclog pores and fade acne marks.

Pros
  • Salicylic acid and glycolic acid target blackheads, pimples and clogged pores.
  • Niacinamide supports marks and uneven tone.
  • Hypoallergenic, non-comedogenic, alcohol-free and paraben-free.
  • Strong track record: 4.8 out of 5 from 28,000 ratings.
  • Price has dropped to $19.00 as recently as November 2, 2026.
Cons
  • Acids can sting or dry out sensitive skin, so start slowly.
  • Night-only use, so it does not replace a morning hydrator.
  • Not for babies or kids.
  • No fragrance-free claim listed.
Olay
Olay Regenerist Collagen Peptide 24 Face Serum

Olay Regenerist Collagen Peptide 24 Serum

Olay Regenerist Collagen Peptide 24 Face Serum

See all prices and details

Choose the Olay Collagen Peptide 24 if you want a fragrance-free, non-exfoliating serum that hydrates for 24 hours and softens fine lines.

Pros
  • Hydrates for 24 hours and can be used morning and night.
  • Fragrance-free and free of parabens, phthalates, mineral oil and synthetic dyes.
  • Collagen peptide and niacinamide aim at plumpness and fine lines.
  • 40 mL is a larger bottle than the Effaclar's roughly 30 mL.
  • Gentler fit for sensitive or dry skin.
Cons
  • No exfoliating acids, so it will not clear clogged pores or blackheads.
  • No price or rating was given, so value is hard to judge.
  • Peptide firming claims build slowly over weeks.
  • Dimethicone-based formula may feel heavy on very oily skin.

What separates them

La Roche-Posay Effaclar SerumOlay Regenerist Collagen Peptide 24 Serum
Main activesSalicylic acid, glycolic acid and niacinamideCollagen peptide (palmitoyl pentapeptide-4) and niacinamide
Primary jobExfoliates to unclog pores and reduce blemishes and marksHydrates, plumps and smooths fine lines
Skin type fitOily, acne-prone and all skin typesAll skin types, including sensitive
When to useNight, once dailyMorning and night
FragranceNot stated as fragrance-free; alcohol-free and paraben-freeFragrance-free
Size1.014 fl oz (about 30 mL)40 mL
TextureLightweight serum in a pipette bottleLight, concentrated serum
Price$34.98 at Shop Simon as of November 8, 2026No price given

Price history

$33.99$19.00
Nov 2Nov 7
  • La Roche-Posay Effaclar Serum: lowest $19.00 on Nov 2 at eBay; $33.99 on Nov 7.
  • Olay Regenerist Collagen Peptide 24 Serum: lowest $31.99 on Nov 3 at Veeha Beauty.

Prices at every store

La Roche-Posay Effaclar Serum

  • TargetNew

    In stock

    $33.99+ $5.99 shippingObserved Nov 7, 2026, 10:52 AM
    Visit Target
  • Ulta BeautyNew

    In stock

    $44.99Free shippingObserved Nov 7, 2026, 10:52 AM
    Visit Ulta Beauty
  • Glams SecretNew

    Availability unknown

    $23.71Checked Nov 2
    Visit Glams Secret
  • cosmetis.comNew

    Availability unknown

    $32.40Checked Nov 6
    Visit cosmetis.com

Also available at

  • FacethefutureCheck price at Facethefuture
  • GiltCheck price at Gilt
  • La Roche PosayCheck price at La Roche Posay

Store links may earn us a commission. Some prices via Klarna.

All 2 stores and price history →

Olay Regenerist Collagen Peptide 24 Serum

  • SwadesiiNew

    Availability unknown

    $34.99Checked Nov 3
    Visit Swadesii
  • eBayNew

    Availability unknown

    $55.37Checked Nov 3
    Visit eBay

Also available at

  • Veeha BeautyCheck price at Veeha Beauty
  • DistaCheck price at Dista
  • IndiangoodsCheck price at Indiangoods

Store links may earn us a commission.

Prices and history →

Specs compared

SpecLa Roche-Posay Effaclar SerumOlay Regenerist Collagen Peptide 24 Serum
Skin TypeOily skin, Acne-prone skin, All Skin TypesAll skin types
EffectMicro-exfoliatesMoisturising, Smoothing
SizeRegular40 mL
ContentGlycolic Acid, AHA Acid, Niacinamide, Salicylic…40 ml
Body PartFace—
FormSerum—
Active IngredientsSalicylic Acid, Glycolic Acid—
Key IngredientSalicylic Acid, Glycolic Acid, Niacinamide—
Skin ConcernsBlemishes, Acne, Breakouts—
Acne Treatment TypeBlackheads, Pimples—
Scar Treatment TypeAcne scars, Acne marks—
SubtypeHydrating serum—
Show all 35 specsShow fewer specs
SpecLa Roche-Posay Effaclar SerumOlay Regenerist Collagen Peptide 24 Serum
TypeSerum—
Face Treatment TypeSerum—
ContainsSalicylic Acid, Glycolic Acid—
Free OfParaben-free—
For BabiesNo—
For KidsNo—
For MenYes—
Night / Day UseNight—
Tattoo CareNo—
Application TimeDaily

What reviewers say

La Roche-Posay Effaclar Serum

  • 4.8 / 528,000 ratings

With about 28,000 ratings averaging 4.8 out of 5, owners largely report fewer blemishes and smoother texture with regular nightly use. Many note it takes weeks to show results and that skin can sting or flake early on.

What people mention
  • BreakoutsPraisedUsers report fewer pimples and blackheads after consistent nightly use.
  • TexturePraisedMany say skin feels smoother and looks more even.
  • IrritationCriticisedSome experience stinging, redness or flaking, especially at the start.
  • Acne marksPraisedOwners say post-acne marks fade over weeks of use.

Olay Regenerist Collagen Peptide 24 Serum

Owners of Olay's peptide serums generally describe a light, fast-absorbing formula that leaves skin soft and hydrated without fragrance. Complaints center on the silicone-heavy feel and on how long visible firming takes.

What people mention
  • TextureMixedUsers call it light and fast-absorbing, but some find the dimethicone finish slippery or tacky.
  • HydrationPraisedOwners report skin feeling moisturized and plump through a full day.
  • FragrancePraisedThe fragrance-free formula suits people who avoid scented skincare.
  • Firming resultsMixedSome see smoother fine lines over weeks; others find the effect subtle.

Questions and answers

Which is better for acne and blackheads?
The Effaclar Serum. Its salicylic and glycolic acids exfoliate inside pores, while the Olay serum has no acids and focuses on hydration.
Which is better for dry or sensitive skin?
The Olay serum. It is fragrance-free, hydrates for 24 hours and has no exfoliating acids that could sting.
Can I use both?
Yes, with care. Use the Effaclar at night and the Olay in the morning, and add the acid slowly if your skin is sensitive.
Is the Effaclar worth the extra?
At $34.98 at Shop Simon as of November 8, 2026, it is the only one of the two that treats blemishes. If clear pores are your goal, it is the one to pay for.
Which lasts longer per bottle?
The Olay, at 40 mL versus about 30 mL for the Effaclar. The Effaclar is night-only, so a bottle still stretches further in days.
Does the Olay serum have fragrance?
No. It is labeled fragrance-free and also free of parabens, phthalates, mineral oil and synthetic dyes.

More comparisons

  • Olay Regenerist Collagen Peptide 24 Face Serum vs Olay Regenerist Micro-Sculpting Serum
  • La Roche-Posay Effaclar Serum vs Regenerist Wrinkle Correcting Night Treatment
  • La Roche-Posay Effaclar Serum vs Olay Regenerist Retinol 24 Night Serum
  • Olay Regenerist Collagen Peptide 24 Face Serum vs The Organic Skin Co Vitamin Sea Serum
  • Rose Glow Anti-Aging Face Serum vs La Roche-Posay Effaclar Serum
  • Mad Hippie Corrective Peptide Serum vs La Roche-Posay Effaclar Serum

Buying guides that pick them

  • Best Olay Regenerist skincare products
—
TextureLightweight—
PackagingPipette—
Skin ConcernWrinkles, Blackheads, Acne—
Volume (fl oz)1.014—
GenderFemale—
Hydration duration—24 hours
Fragrance—Fragrance-Free
Key ingredients—Collagen Peptide and Vitamin B3+
Time of care—Day
Length—12.40 cm
Width—4.30 cm
Height—4.40 cm
Weight—75 g