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SanDisk Optimus 5100 4TB NVMe SSD vs SanDisk Extreme 64 GB microSDXC

These are not rivals. The Optimus 5100 is a 4 TB internal M.2 NVMe drive for a PC or laptop slot. The Extreme is a 64 GB microSDXC card for cameras, drones, phones and handhelds. Buy the Optimus 5100 to expand fast internal storage. Buy the Extreme to record video or add storage to a device with a card slot. The Optimus 5100 has few ratings but strong sequential speeds; the Extreme has a large, satisfied owner base.

  • Choose the SanDisk Optimus 5100 if you need a large, fast internal drive for a desktop or laptop with an M.2 2280 slot.
  • Choose the SanDisk Extreme microSDXC if you need removable storage for a camera, drone, action cam, phone or handheld console.

Prices

  • SanDisk Optimus 5100 4TB NVMe SSD: $99.99 at Central Computers (last seen Nov 6)
  • SanDisk Extreme 64 GB microSDXC: $61.49 at Walmart (last seen Nov 8)
  • Difference: the SanDisk Extreme 64 GB microSDXC is $38.50 cheaper than the SanDisk Optimus 5100 4TB NVMe SSD at the latest prices (Nov 6 and Nov 8)
SanDisk
SanDisk Optimus 5100

SanDisk Optimus 5100 4TB NVMe SSD

SanDisk Optimus 5100

4.5(31 ratings)
$99.99at Central ComputersObserved Nov 6, 2026, 1:37 PM
See all prices and details
Visit Central Computers
Pros
  • 4 TB in a single M.2 2280 drive
  • Very fast sequential reads and writes
  • NVMe over PCIe for low latency
  • Fits most modern desktops and laptops
Cons
  • Needs an open M.2 slot and a screw
  • No heatsink listed, so check clearance
  • Few ratings so far
  • Not removable or portable
SanDisk
SanDisk Extreme 64 GB microSDXC A2 V30

SanDisk Extreme 64 GB microSDXC

SanDisk Extreme 64 GB microSDXC A2 V30

4.8(150 ratings)
$61.49at WalmartObserved Nov 8, 2026, 6:48 PM
See all prices and details
Visit Walmart
Pros
  • Rated V30 and U3 for 4K video
  • A2 class speeds up app loading on phones and handhelds
  • Works across cameras, drones and consoles
  • High owner rating from many buyers
Cons
  • Only 64 GB
  • Slow next to any NVMe drive
  • UHS-I interface caps speed
  • Easy to lose at its small size

What separates them

SanDisk Optimus 5100 4TB NVMe SSDSanDisk Extreme 64 GB microSDXC
Device typeInternal M.2 2280 NVMe SSDRemovable microSDXC card
Capacity4 TB64 GB
Sequential readUp to 6,900 MB/sUp to 160 MB/s
Sequential writeUp to 6,700 MB/sUp to 60 MB/s
InstallationScrewed into an M.2 slot on the motherboardSlots into a card reader or tray
Video recording classNot rated for camera videoV30, U3, Class 10 for 4K capture
App performanceNot applicableA2 rated for running apps from the card
PortabilityStays inside one machineMoves between devices

Price history

$787.93$30.00
Nov 3Nov 9
  • SanDisk Optimus 5100 4TB NVMe SSD: lowest $99.99 on Nov 3 at Central Computers; $787.93 on Nov 9.
  • SanDisk Extreme 64 GB microSDXC: lowest $30.00 on Nov 8 at diagnoex.com; $30.00 on Nov 9.

Prices at every store

SanDisk Optimus 5100 4TB NVMe SSD

  • Central ComputersNew

    Availability unknown

    $99.99Observed Nov 6, 2026, 1:37 PM
    Visit Central Computers
  • Newegg.comNew

    Availability unknown

    $108.99Observed Nov 3, 2026, 7:22 AM
    Visit Newegg.com
  • B&H Photo-Video-AudioNew

    Availability unknown

    $109.99Observed Nov 6, 2026, 1:37 PM
    Visit B&H Photo-Video-Audio
  • Best BuyNew

    Availability unknown

    $109.99Observed Nov 6, 2026, 1:37 PM
    Visit Best Buy
All 17 stores and price history →

SanDisk Extreme 64 GB microSDXC

  • WalmartNew

    In stockSold by First Choice Online

    $61.49+ $10.99 shippingObserved Nov 8, 2026, 6:48 PM
    Visit Walmart
  • Lowe'sNew

    In stock

    $78.99Free shippingObserved Nov 8, 2026, 6:48 PM
    Visit Lowe's
  • Newegg.comNew

    In stock

    $84.99Free shippingObserved Nov 8, 2026, 6:48 PM
    Visit Newegg.com
  • Central ComputersNew

    In stock

    $62.99+ $35.80 shippingObserved Nov 8, 2026, 6:48 PM
    Visit Central Computers

Also available at

  • AmazonCheck price at Amazon
  • Techinn.comCheck price at Techinn.com
  • PADI-DjaCheck price at PADI-Dja
All 5 stores and price history →

Specs compared

SpecSanDisk Optimus 5100 4TB NVMe SSDSanDisk Extreme 64 GB microSDXC
TypeInternalNVMe SSD
Form FactorM.2 2280M.2
Capacity4 TB128 GB
Read Speed6,900 MB/s5150 MB/s
Write Speed6,700 MB/s write speed800K IOPS (random write)
ColorBlueRed
ConnectionM.2—
NVMeYes—
Use—Internal
Device Compatibility—PC
Interface—PCIe Gen 4.0
Wireless Connectivity—No
Show all 39 specsShow fewer specs
SpecSanDisk Optimus 5100 4TB NVMe SSDSanDisk Extreme 64 GB microSDXC
Durability—Durable
NVMe Support—Yes
PCIe Support—Yes
Cache—nCache 4.0 technology
Design Highlights—Compact
Typical Users—Creative professionals
SD Format—microSDXC
Format—SD
Video Speed Class—V30
SD Type—

What reviewers say

SanDisk Optimus 5100 4TB NVMe SSD

  • 4.5 / 531 ratings

Owners rate it 4.5 out of 5 from 31 ratings, with most praise going to speed and capacity for the money. A few mention heat under long writes.

What people mention
  • SpeedPraisedOwners say reads and writes feel near the rated 6,900/6,700 MB/s in everyday use.
  • CapacityPraisedBuyers like fitting 4 TB into a single M.2 slot instead of juggling several drives.
  • HeatMixedSome report the drive gets warm during long writes, especially without a heatsink.
  • Sustained writesCriticisedA few note speeds fall on very large transfers once the cache is used up.

SanDisk Extreme 64 GB microSDXC

  • 4.8 / 5150 ratings

Rated 4.8 out of 5 from 150 ratings, buyers mostly report it working as expected in cameras, drones and phones. Complaints center on capacity and speed limits rather than failures.

What people mention
  • ReliabilityPraisedOwners say the card holds up in cameras and drones without corruption.
  • CapacityCriticisedBuyers note 64 GB fills fast when recording 4K or storing large games.
  • SpeedMixedV30 and A2 ratings are fine for most uses, but UHS-I caps out below faster cards.
  • ValuePraisedReviewers call it an affordable way to add storage.

Questions and answers

Can I use the Optimus 5100 in a laptop?
Yes, if the laptop has an M.2 2280 slot that accepts a double-sided or full-length drive. Check the slot length and clearance before buying. Many thin laptops only take shorter 2230 drives.
Is the Extreme card fast enough for 4K video?
Yes. Its V30 rating guarantees a sustained write speed suitable for 4K video in cameras and drones. It is not meant for high-bitrate 8K or raw capture.
Which one should I buy for a Steam Deck or Switch?
The Extreme microSDXC. Those devices use a card slot, not a full-size M.2 drive. The A2 rating also helps app and game loading.
Which lasts longer?
The Optimus 5100 is built for years of heavy internal use and has a much larger capacity to spread writes. The Extreme is durable but a small card that sees wear from constant recording and is easy to lose.
Is the Optimus 5100 worth stepping up to over a smaller SSD?
If you need 4 TB of fast internal storage for games, video or large project files, yes. If you only need a boot drive or portable storage, a smaller drive or a card is enough.
Do either of these need a heatsink?
The Optimus 5100 runs fast and benefits from a motherboard heatsink or airflow in a desktop. The Extreme card generates little heat and needs none.

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  • ADATA SU650 512GB Internal SSD vs SanDisk Extreme 64 GB microSDXC A2 V30
microSDXC
Memory Size—64 GB
Wi-Fi—No
Speed Class—Class 10
App Performance Class—A2
Write Speed (MB/s)—60
UHS Interface—UHS-I
UHS Speed Class—U3
Read Speed (MB/s)—160
SD Speed Class—Class 10, UHS Class 1, UHS Class 3
Multipack Qty—2-pack
size—GB
Data Encryption—256-bit AES hardware encryption
Security Highlights—Password protection, 256-bit AES hardware encry…
Hot Swappable—Yes, Hot Plug Support
Power Source—Bus Powered
Power Consumption—3600 W
Removable—Yes