Is Advantage II worth it over a chewable flea pill?

Advantage II is cheaper per month and also kills eggs and larvae in the dog's surroundings, which many pills don't. Chewables are easier to give and some add tick coverage, so pick based on whether ticks are a concern.

No. Advantage II targets fleas only: adults, eggs and larvae. If ticks are a problem in your area, you need a product with a tick-active ingredient.

How often do I apply it, and can my dog swim?

Apply once a month. The formula is waterproof after 24 hours, so swimming and bathing are fine after that first day.

Which weight box do I need?

This box is for dogs 21–55 lbs. Advantage II comes in separate sizes for smaller and larger dogs, and the dose should match your dog's weight.

Can I use it on cats or puppies?

Never use it on cats. For dogs, it is labeled for puppies 7 weeks and older; check the box for the minimum weight that matches the size you buy.

When is the price lowest?

Multi-month packs usually cost less per dose than single doses, and the 6-count at $30.99 at PetSmart as of November 4, 2026 is the best new price among the five stores listing it.

Where is the Advantage II Flea & Tick Dog cheapest?

At PetSmart, for $30.99, 39% under what the other stores charge, as of our latest check.

Where can I buy the Advantage II Flea & Tick Dog?

7 stores we checked sell it, including PetSmart, Petco.com, Walmart, Chewy.com, Allivet Pet Pharmacy.

Advantage II Flea & Tick Dog

Best price now

$30.99at PetSmartObserved at 5:34 AM

39% under what the other stores charge

Compared across 5 stores. Prices are checked against each store and labelled with when.

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Our take on the Advantage II Flea & Tick Dog

Advantage II is a monthly topical flea treatment for dogs that kills adult fleas, eggs and larvae with imidacloprid and pyriproxyfen. It starts killing fleas within 12 hours and stays waterproof after 24 hours, so bathing or swimming doesn't stop it working. The 6-count pack covers about four months for one dog. At $30.99 at PetSmart as of November 4, 2026, it is the lowest of the five stores listing it new, so the current price sits at the bottom of its recent range.

Best forOwners of dogs in the 21–55 lb weight range

What reviewers say

Owners generally find Advantage II effective at clearing fleas and stopping reinfestation, and like that it is scent-free and waterproof. Complaints tend to be about the topical residue and about fleas returning if doses are missed.

Pros

Clears fleas quickly, often within a day
No strong smell
Holds up through baths and swimming
Breaks the flea life cycle so infestations don't bounce back

Cons

Oily spot at the application site
Needs strict monthly timing to keep working
No tick coverage

About the Advantage II Flea & Tick Dog

Help protect your precious pooch from parasitic pests and the potentially harmful diseases they can transmit with Advantage II Flea Treatment for Medium Dogs. This highly-effective, veterinarian-recommended treatment is specifically formulated to kill all life stages of fleas on contact with no painful biting required. With three-way protection that kills the eggs, larvae and adults, it breaks the flea life-cycle to help prevent re-infestation of both your house and hound. The waterproof formula for dogs 7 weeks or older and weighing between 11 and 20 pounds continues working for up to four weeks, even after bathing or swimming.

Key Benefits

• Veterinarian-recommended treatment kills all life stages of fleas on puppies and dogs 7 weeks or older and weighing 11-20 pounds.

• Begins working within 12 hours to kill fleas on contact.

• Kills eggs, larvae and adult fleas to break the life cycle and help prevent re-infestation.

• Waterproof formula continues working for up to four weeks, even after bathing or swimming.

• Convenient, monthly topical application contains imidacloprid and pyriproxyfen; available in packs of 4 or 6 treatments.