StoreDeal.ai store
Shop
  • Deals
  • Deal checker
  • Black Friday
  • Buying guides
  • Brands
  • Stores
Travel
  • Flight deals
  • Hotel deals
Company
  • Research
  • Press
  • Use in AI assistants
  • Contact
  • deal.ai apps
Black Friday 2026
  • Walmart
  • Best Buy
  • Target
  • TVs
  • Laptops
  • Headphones
  • Apple
  • Gaming
  • Vacuums
  • Kitchen
  • Toys
  • Smartwatches
  • Tablets
  • Furniture
  • Mattresses
© Deal.ai Inc.·2222 Ponce de Leon Blvd, Miami, FL 33134·support@deal.ai
TermsPrivacy
Deal.ai › Differin
Differin
Differin 0.1% Acne Treatment Gel, 0.5 oz

Differin 0.1% Acne Treatment Gel, 0.5 oz

Best price now

$37.98at EasyOptionXYChecked Nov 8

Prices are checked against each store and labelled with when.

Visit EasyOptionXY

Ask our agent about this product

It checks today's price at every store, compares the alternatives and answers in about a minute.

Enter to send, Shift+Enter for a new line

Price facts

  • Last seen at $37.98 at EasyOptionXY on Nov 8.

Our take on the Differin 0.1% Acne Treatment Gel, 0.5 oz

Differin Gel is an over-the-counter acne treatment built on adapalene 0.1%, a topical retinoid that was prescription-only before it moved to OTC shelves. It works inside the pore to clear existing breakouts and prevent new ones, and it also helps with blackheads, whiteheads and clogged pores over time. It suits people with mild to moderate acne who want a retinoid without a prescription, and it is a stronger, slower-acting option than benzoyl peroxide or salicylic acid washes. Most users need weeks of consistent use and a moisturizer to get through the early dryness and purge phase.

Best forTeens and adults with mild to moderate acnePeople who want an OTC retinoid instead of a prescriptionBlackheads, whiteheads and clogged poresFace and body breakout treatment
Pros
  • Adapalene 0.1% is a proven retinoid, the same class as prescription acne drugs
  • Treats existing breakouts and helps prevent new ones
  • Also improves blackheads, whiteheads and clogged pores
  • Can be used on the face and body
  • Fragrance-free gel that layers under moisturizer
Cons
  • Dryness, peeling and irritation are common in the first weeks
  • Skin can look worse before it clears (purging)
  • Results take weeks, not days, with daily use
  • Sun sensitivity rises, so daily sunscreen is needed
  • Not for anyone pregnant or planning pregnancy without a doctor's advice

Differin 0.1% Acne Treatment Gel, 0.5 oz prices at every store

  • EasyOptionXYNew

    In stockReturn policy

    $37.98Checked Nov 8
    Visit EasyOptionXY

What reviewers say

Reviewers rate Differin highly as an effective, affordable retinoid, and many call it the product that finally cleared their acne. Most say it takes patience: dryness, flaking and a breakout purge in the first month are common before skin improves.

What people mention
  • DrynessCriticisedMany users report flaking, tightness and redness in the first weeks, especially when they start daily.
  • PurgingCriticisedSome see more breakouts before skin clears, which leads people to quit too early.
  • EffectivenessPraisedReviewers who stick with it say blackheads and persistent acne clear over one to three months.
  • TexturePraisedThe gel is light, spreads easily and sits well under moisturizer and sunscreen.
  • Sunscreen needMixedUsers note skin becomes more sun-sensitive, so daily SPF becomes mandatory.

About the Differin 0.1% Acne Treatment Gel, 0.5 oz

Differin Gel is an acne treatment for the face and body. Its active ingredient is adapalene 0.1%, a retinoid that was the first new over-the-counter acne ingredient in more than 30 years. It has Rx-strength acne-fighting power without a prescription.

The gel works deep into pores in 5 minutes to help clear breakouts where they start. It helps prevent new acne from forming, including blackheads, whiteheads, blemishes and clogged pores. As a result, it can restore skin's overall tone and texture.

Results can begin in as little as 1 week when used as directed. Used every day, the gel can help reduce up to 87% of acne in 12 weeks.

Active ingredient
Adapalene 0.1%
Type
Acne treatment gel, retinoid
Use on
Face and body
Net contents
0.5 oz
Time to results
As little as 1 week; up to 87% acne reduction in 12 weeks with daily use

Questions and answers

How long until Differin Gel works?
Some people see improvement in about a week, but steady daily use is what counts. The brand cites up to 87% acne reduction at 12 weeks, so judge it after two to three months.
How is it different from benzoyl peroxide or salicylic acid?
Differin uses adapalene, a retinoid that works inside the pore and helps prevent new acne. Benzoyl peroxide and salicylic acid are not retinoids and act mainly on surface bacteria and clogging.
Can I use it with other acne products?
It can be combined, but stacking it with strong acids or benzoyl peroxide at the start raises irritation. Many users alternate nights or use a gentle moisturizer alongside it.
How should I apply it?
Apply a thin layer to clean, dry skin once daily, typically at night, and use sunscreen every morning. A pea-sized amount covers the whole face.
Is it safe for sensitive skin?
It can be, but start slowly, every other night, and build up. If irritation is severe or persists, stop and ask a doctor or pharmacist.
Can I use it on my back and chest?
Yes, the label covers face and body use. Apply thinly to affected areas and expect the same dryness and adjustment period.
Where is the Differin 0.1% Acne Treatment Gel, 0.5 oz cheapest?
At EasyOptionXY, for $37.98, as of our latest check.

More from Differin

  • D
    Differin Acne Treatment Adapalene Gel
    Differin Acne Treatment Adapalene Gel
  • D
    Differin Gel (0.1%)
    Differin Gel (0.1%)
  • D
    Differin Adapalene Gel 0.1% Acne Treatment
    Differin Adapalene Gel 0.1% Acne Treatment
  • D
    Differin Acne Spot Treatment with 10% Benzoyl Peroxide
    Differin Acne Spot Treatment with 10% Benzoyl Peroxide
  • D
    Differin Prescription-Strength Retinoid Acne Treatment Gel for Face with 0.1% Adapalene
    Differin Prescription-Strength Retinoid Acne Treatment Gel for Face with 0.1% Adapalene
  • D
    Differin Epiduo Acne Gel Treatment
Differin Epiduo Acne Gel Treatment
  • D
    Differin Epiduo Pump 1.6oz with Adapalene 0.1% and Benzoyl Peroxide 2.5% Gel
    Differin Epiduo Pump 1.6oz with Adapalene 0.1% and Benzoyl Peroxide 2.5% Gel
  • All Differin deals and products →

    More acne treatments

    • P
      PanOxyl 10% Acne Treatment Bar
      PanOxyl 10% Acne Treatment Bar
    • P
      Panoxyl Acne Creamy Wash Daily Control
      Panoxyl Acne Creamy Wash Daily Control
    • S
      Stridex Medicated Acne Pads for Sensitive Skin
      Stridex Medicated Acne Pads for Sensitive Skin
    • A
      Acne Treatment Dots
      Acne Treatment Dots
    • A
      Acne Med 10%
      Acne Med 10%
    • T
      Thayers Rapid Acne Treatment with 10% Sulfur, Niacinamide, Glycolic Acid
      Thayers Rapid Acne Treatment with 10% Sulfur, Niacinamide, Glycolic Acid
    • N
      Neutrogena Rapid Clear Acne Eliminating Spot Treatment Gel
      Neutrogena Rapid Clear Acne Eliminating Spot Treatment Gel
    • Z
      Zapzyt Acne Treatment Gel, Maximum Strength 10 Percent Benzoyl Peroxide
      Zapzyt Acne Treatment Gel, Maximum Strength 10 Percent Benzoyl Peroxide