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Deal.ai › SDA LABORATORIES
SDA Laboratories
Diphenhydramine HCl 50mg Antihistamine Medicine - 1000 Capsules
SDA Laboratories

Diphenhydramine HCl 50mg Antihistamine Medicine - 1000 Capsules

Best price now

$29.99at AmazonObserved at 11:55 PM

Compared across 4 stores. Prices are checked against each store and labelled with when.

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Our take on the Diphenhydramine HCl 50mg Antihistamine Medicine - 1000 Capsules

A 1,000-capsule bottle of diphenhydramine 50 mg capsules from SDA Laboratories. Diphenhydramine is a first-generation antihistamine used for allergy and sinus symptoms and for motion sickness, and it causes drowsiness in most people. The 50 mg dose is double the common 25 mg tablet, so each capsule is a full adult night-time or allergy dose. At $29.99 at Amazon as of November 7, 2026, it works out to about 3 cents per capsule, a low per-dose cost for a bulk supply.

Best forHouseholds that use diphenhydramine regularlyAllergy and sinus symptom reliefMotion sickness on tripsBuying a long-lasting bulk supply
Pros
  • Very low cost per capsule at about 3 cents
  • 1,000 capsules last a long time
  • Single active ingredient, easy to dose
  • 50 mg strength is a full adult dose
  • Capsule form is easy to swallow
Cons
  • Causes drowsiness; not for daytime driving or work
  • 50 mg is too strong for children and some adults
  • Bulk bottle needs a dry, child-safe storage spot
  • Not for people who need a non-drowsy antihistamine
  • Long-term daily use should be checked with a doctor

Diphenhydramine HCl 50mg Antihistamine Medicine - 1000 Capsules prices at every store

  • AmazonNew

    Availability unknown

    As an Amazon Associate, Deal.ai earns from qualifying purchases.

    $29.99Observed at 11:55 PM
    Visit Amazon
  • Hey PharmaNew

    Out of stock

    $32.16Free shippingObserved at 11:55 PM
    Visit Hey Pharma
  • WalmartNew

    Out of stock

    $25.90+ $6.99 shippingObserved at 11:55 PM
    Visit Walmart
  • VitalityMedical.comNew

    Out of stock

    $34.37+ $8.75 shippingObserved at 11:55 PM
    Visit VitalityMedical.com

Diphenhydramine HCl 50mg Antihistamine Medicine - 1000 Capsules price history

Lowest price we've seen: $25.90 on Nov 7 at Walmart. Tracked across 4 stores since Nov 7.

Specifications

Form
Capsule
Active Ingredient
Diphenhydramine

Questions and answers

Is 50 mg of diphenhydramine a standard dose?
It is a full adult dose; the common tablet is 25 mg. Adults often take 25 to 50 mg, so one capsule covers a night-time or strong allergy dose. Children need a lower dose and should not take these capsules.
Can I take this during the day?
Most people feel drowsy after diphenhydramine. It is best taken at bedtime or when you do not need to drive or operate machinery. For daytime allergy relief, a non-drowsy antihistamine such as loratadine or cetirizine is a better fit.
Does it help with motion sickness?
Yes. Diphenhydramine is used for motion sickness and nausea. Take it about 30 minutes before travel, and expect drowsiness.
How long will 1,000 capsules last?
At one capsule a night, the bottle lasts about 2.7 years. Check the expiration date on the bottle and store it in a dry place.
Is this the same as Benadryl?
The active ingredient is the same, diphenhydramine hydrochloride. These are generic 50 mg capsules, stronger than the standard 25 mg Benadryl tablet, so adjust the dose accordingly.
Can I take it with other allergy medicine?
Do not combine it with other antihistamines or sleep aids without asking a pharmacist, since the sedative effect adds up. Check labels on cold and flu products, which often contain diphenhydramine.
Where is the Diphenhydramine HCl 50mg Antihistamine Medicine - 1000 Capsules cheapest?
At Amazon, for $29.99, as of our latest check.
Where can I buy the Diphenhydramine HCl 50mg Antihistamine Medicine - 1000 Capsules?
4 stores we checked sell it, including Amazon, Walmart, Hey Pharma, VitalityMedical.com.

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Stores we've priced the Diphenhydramine HCl 50mg Antihistamine Medicine - 1000 Capsules at

  • Walmart deals and prices