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Deal.ai › iS Clinical › Serums & Face Oils
iS Clinical
iS Clinical Active Serum

iS Clinical Active Serum

4.7(2,700 ratings)

Best price now

$89.99at TargetChecked 8 h ago

42% under what the other stores charge

Compared across 8 stores. Prices are checked against each store and labelled with when.

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Price facts

  • Last seen at $89.99 at Target on Nov 9.
  • Checked at 8 stores.

Our take on the iS Clinical Active Serum

Active Serum is a lightweight exfoliating treatment built on glycolic and salicylic acids with white willow bark, bilberry, sugarcane and mushroom extracts. It targets acne, uneven tone, fine lines and acne scarring, and most users apply it at night. Reviewers with oily and acne-prone skin report clearer pores and smoother texture, while sensitive users often find it tingling or drying at first. It sits at the strong end of the exfoliating serum market, closer to a peel than to a hydrating serum.

Best forOily and acne-prone skinAdult acne with fine linesUneven tone and post-acne marksExperienced acid users wanting a nightly exfoliant
Pros
  • Combines glycolic and salicylic acids for surface and pore exfoliation
  • Lightweight, fast-absorbing texture
  • Botanical extracts plus arbutin support brightening
  • Paraben-free formula
  • Popular with long-term users for texture and breakouts
Cons
  • Can sting or tingle, especially on sensitive skin
  • Drying if used too often or layered with other acids
  • Not for babies or kids
  • Results build slowly and need consistent nightly use

iS Clinical Active Serum prices at every store

  • TargetNew

    In stock

    $89.99Checked 8 h ago
    Visit Target
  • ShopSimonNew

    In stock

    $111.67Checked 8 h ago
    Visit ShopSimon
  • BluemercuryNew

    In stock

    $155.00Checked 8 h ago
    Visit Bluemercury
  • Dermstore.comNew

    In stock

    $155.00Checked 8 h ago
    Visit Dermstore.com
  • WalmartNew

    Availability unknownSold by Beauty Guarantee

    $106.27Checked 8 h ago
    Visit Walmart
  • Lookfantastic USNew

    Availability unknown

    $142.00Checked 8 h ago
    Visit Lookfantastic US
  • LovelySkin.comNew

    Availability unknown

    $155.00Checked 8 h ago
    Visit LovelySkin.com
  • Art of Skin CareNew

    Availability unknown

    $155.00Checked 8 h ago
    Visit Art of Skin Care

Also available at

  • JomashopCheck price at Jomashop
  • Violet GreyCheck price at Violet Grey
  • Mayo Clinic StoreCheck price at Mayo Clinic Store
  • Shop SimonCheck price at Shop Simon
  • Aloha MedCheck price at Aloha Med
  • iS ClinicalCheck price at iS Clinical
  • International OrangeCheck price at International Orange
  • Chelsea's Esthetic BoutiqueCheck price at Chelsea's Esthetic Boutique
  • BluemercuryCheck price at Bluemercury

iS Clinical Active Serum price history

Lowest price we've seen: $89.99 on Nov 10 at Target. Tracked across 17 stores since Nov 10.

What reviewers say

  • 4.7 / 52,700 ratings

Rated 4.7 out of 5 across about 2,700 ratings, with most praise for clearer skin, smaller-looking pores and smoother texture. Complaints center on stinging, dryness and irritation, mostly from people with sensitive skin.

What people mention
  • IrritationMixedMany users feel tingling or stinging on application, which some tolerate and others find uncomfortable.
  • BreakoutsPraisedAcne-prone users report fewer blackheads and clearer skin after several weeks.
  • TexturePraisedReviewers say skin feels smoother and looks more refined with regular nightly use.
  • DrynessCriticisedSome users find it drying and need a moisturizer on top, especially in winter.
  • BrighteningPraisedUsers mention fading of post-acne marks and a more even tone.

About the iS Clinical Active Serum

Give your skin the nourishment it deserves with a serum. This serum & face oil is suitable for oily skin.

Specifications

Body Part
Face
Form
Serum
Skin Type
All skin types, Acne-prone skin
Key Ingredient
White Willow Bark, Bilberry, Mushroom, Sugarcane
Skin Concerns
Uneven skin tone, Acne, Fine lines and wrinkles
Acne Treatment Type
Whiteheads, Blackheads
Scar Treatment Type
Acne scarring

Questions and answers

How do I use Active Serum?
Apply a few drops to clean, dry skin at night, then follow with moisturizer. Start two or three nights a week and build up as your skin tolerates it.
Is it safe for sensitive skin?
It contains glycolic and salicylic acids, so sensitive skin may sting or flush. Patch test first and avoid pairing it with retinoids or other acids on the same night.
Can I use it during the day?
It is designed for nightly use. If you apply it in the morning, follow with a broad-spectrum sunscreen, since acids increase sun sensitivity.
How does it compare with other iS Clinical serums?
Active Serum is the exfoliating, acne-focused option. Pro-Heal Serum is the gentler antioxidant choice for redness and reactive skin, and Hydra-Cool is the hydrating pick.
How long until I see results?
Most users notice smoother texture within a few weeks. Fading of marks and softening of fine lines usually takes a couple of months of consistent use.
What is in the bottle?
A 30 mL pipette bottle of serum. The formula includes glycolic acid, salicylic acid, white willow bark, bilberry, sugarcane, mushroom extract, arbutin and glycerin, and is paraben-free.
Where is the iS Clinical Active Serum cheapest?
At Target, for $89.99, 42% under what the other stores charge, as of our latest check.
What do buyers say about the iS Clinical Active Serum?
Rated 4.7 out of 5 from 2,700 ratings.
Where can I buy the iS Clinical Active Serum?
16 stores we checked sell it, including Target, Walmart, ShopSimon, Lookfantastic US, Bluemercury.

Stores we've priced the iS Clinical Active Serum at

  • Bluemercury deals and prices
  • ShopSimon deals and prices
  • Target deals and prices
  • Walmart deals and prices

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Subtype
Hydrating serum, Anti-aging moisturizer
Type
Serum
Face Treatment Type
Serum
Contains
Glycerin, Arbutin, Butylene Glycol, Glyceryl Polyacrylate, Glycolic acid
Free Of
Paraben-free
For Babies
No
For Kids
No
For Men
Yes
Effect
Exfoliating
Size
30 mL e 1 fl. oz.
Night / Day Use
Night
Tattoo Care
No
Application Time
Nightly, At night
Texture
Lightweight
Suitable For
All skin types
Content
Glycolic Acid, Salicylic AcidSource
Packaging
PipetteSource