How does it compare with the Tune 770NC?

Both are over-ear Tune models with ANC and Bluetooth. The 780NC is the newer number in the line; check the listed battery rating and driver size on each before choosing, since JBL changes those between models.

Does it work with iPhone and Android?

Yes. It connects over standard Bluetooth, so it pairs with iOS and Android phones as well as laptops and tablets.

Can I take calls with it?

Yes. It has a built-in microphone, so you can use it for calls and video meetings over Bluetooth.

What comes in the box?

Expect the headphones and a charging cable. A carry case and audio cable are not confirmed for this model, so check the listing before buying.

Is the JBL Tune 780NC worth it?

It is a reasonable entry into active noise cancelling from a known audio brand. If you need strong ANC for flights, step up to JBL's higher lines; for daily commuting and calls, it covers the basics.