How does 0.05% compare with 0.025% or 0.1% tretinoin?

0.05% sits in the middle: more potent than 0.025% starter strength but gentler than 0.1%. A dermatologist can adjust strength based on your tolerance.

How long until I see results?

Many users notice improvement in six to twelve weeks, with fuller clearing over several months. Consistency matters more than speed.

Can I use it with other acne products?

Ask your prescriber. Combining with benzoyl peroxide, salicylic acid or strong exfoliants can raise irritation; many routines alternate or buffer with moisturizer.

Yes. Tretinoin increases sun sensitivity, so use a broad-spectrum sunscreen daily and avoid excess sun exposure.

Is it safe during pregnancy?

Tretinoin is generally avoided in pregnancy and breastfeeding. Talk to your healthcare professional before use.

How should I apply it?

Apply a thin layer to clean, dry skin once daily, usually at night, avoiding eyes, mouth and sensitive areas. Use only as directed by your prescriber.

Where is the Obagi Tretinoin 0.05% Cream cheapest?

At Skinsolutions.md, for $95.00, as of our latest check.

Where can I buy the Obagi Tretinoin 0.05% Cream?

3 stores we checked sell it, including Skinsolutions.md, Totality Medispa and Skincare, ShopSimon.

Obagi Tretinoin 0.05% Cream

Best price now

$95.00at Skinsolutions.mdChecked Nov 12

Prices are checked against each store and labelled with when.

Visit Skinsolutions.md

Obagi discount code →

Obagi Tretinoin 0.05% Cream

Best price now

$95.00at Skinsolutions.mdChecked Nov 12

Prices are checked against each store and labelled with when.

Visit Skinsolutions.md

Obagi discount code →

Ask our agent about this product

It checks today's price at every store, compares the alternatives and answers in about a minute.

Price facts

Last seen at $95.00 at Skinsolutions.md on Nov 12.

Our take on the Obagi Tretinoin 0.05% Cream

Obagi Tretinoin 0.05% Cream is a prescription-strength topical retinoid used to manage acne vulgaris and improve skin texture. It is fragrance free and formulated for combination, normal-to-dry and normal-to-oily skin. Tretinoin is the most-studied acne retinoid, and 0.05% is a mid-strength concentration, stronger than starter 0.025% but milder than 0.1%. Expect peeling, dryness and redness in the first weeks while skin adjusts.

Best forPeople with mild to moderate acne who want a proven retinoidCombination or oily skin prone to clogged poresUsers following a dermatologist's acne planAdults also targeting uneven texture and tone

Pros

Tretinoin is a well-established, effective acne ingredient
Mid-strength 0.05% balances potency and tolerability
Fragrance free, so less likely to irritate
Cream base suits normal-to-dry skin
Also improves the look of uneven texture over time

Cons

Prescription required, not an over-the-counter product
Common early irritation: peeling, dryness, redness
Increases sun sensitivity, so daily sunscreen is essential
Results take weeks to months of consistent use
Not for pregnancy or breastfeeding without medical advice

Obagi Tretinoin 0.05% Cream prices at every store

Skinsolutions.mdNew
In stockShips from Moldova · duties may apply
$95.00Free shippingChecked Nov 12
Visit Skinsolutions.md

Also available at

Totality Medispa and SkincareCheck price at Totality Medispa and Skincare
ShopSimonCheck price at ShopSimon

Obagi Tretinoin 0.05% Cream price history

Lowest price we've seen: $95.00 on Nov 12 at Skinsolutions.md. Tracked across 1 store since Nov 12.

What reviewers say

4.5 / 515 ratings

Rated 4.5 out of 5 from 15 ratings. Users report clearer skin and smoother texture with consistent use, while some mention the expected dryness and peeling during the adjustment period.

What people mention

EffectivenessPraisedUsers say breakouts and texture improve with regular use.
DrynessCriticisedMany report flaking and tightness in the first weeks.
IrritationMixedSome see redness and stinging early, easing as skin adjusts.
TexturePraisedThe cream base feels smooth and spreads thinly.
Results timelineMixedUsers note it takes weeks before changes show.

About the Obagi Tretinoin 0.05% Cream

Obagi Tretinoin 0.05% Cream is a prescription-strength topical treatment for acne vulgaris. It promotes skin renewal to help reduce the look of blemishes and improve skin texture. With consistent use under medical guidance, it helps unclog pores and minimize breakouts.

The cream is fragrance free. It suits combination, normal to dry, and normal to oily skin types.

Use it only as directed by a healthcare professional. Apply a small amount to clean, dry skin once daily, typically in the evening. Spread a thin layer over the affected areas and avoid the eyes, mouth, and sensitive skin. Tretinoin may increase sun sensitivity, so apply sunscreen during the day.

Active ingredient: Tretinoin 0.05%
Form: Cream
Strength: Prescription strength
Used for: Acne vulgaris, blemishes, uneven skin texture
Skin type: Combination, normal to dry, normal to oily
Formula: Fragrance free
Directions: Thin layer on clean, dry skin once daily, typically in the evening
Cautions: Avoid eyes, mouth, and sensitive skin; use sunscreen in the daytime

Questions and answers

How does 0.05% compare with 0.025% or 0.1% tretinoin?: 0.05% sits in the middle: more potent than 0.025% starter strength but gentler than 0.1%. A dermatologist can adjust strength based on your tolerance.
How long until I see results?: Many users notice improvement in six to twelve weeks, with fuller clearing over several months. Consistency matters more than speed.
Can I use it with other acne products?: Ask your prescriber. Combining with benzoyl peroxide, salicylic acid or strong exfoliants can raise irritation; many routines alternate or buffer with moisturizer.
Do I need sunscreen?: Yes. Tretinoin increases sun sensitivity, so use a broad-spectrum sunscreen daily and avoid excess sun exposure.
Is it safe during pregnancy?: Tretinoin is generally avoided in pregnancy and breastfeeding. Talk to your healthcare professional before use.
How should I apply it?: Apply a thin layer to clean, dry skin once daily, usually at night, avoiding eyes, mouth and sensitive areas. Use only as directed by your prescriber.
Where is the Obagi Tretinoin 0.05% Cream cheapest?: At Skinsolutions.md, for $95.00, as of our latest check.
What do buyers say about the Obagi Tretinoin 0.05% Cream?: Rated 4.5 out of 5 from 15 ratings.
Where can I buy the Obagi Tretinoin 0.05% Cream?: 3 stores we checked sell it, including Skinsolutions.md, Totality Medispa and Skincare, ShopSimon.