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P-TIOX is SkinCeuticals' peptide-based anti-wrinkle serum, built around a neuropeptide blend plus niacinamide and a PHA exfoliant. It targets expression lines and fine wrinkles without the irritation that comes with retinoids, so it suits people who want an alternative to retinol or who are easing into anti-aging actives. It is fragrance-free and lighter than the brand's antioxidant serums, which makes it easier to layer under moisturizer and sunscreen. Compared with retinol serums, it is gentler and faster to tolerate, but it works more gradually and is not a substitute for a retinoid if deep lines are your main concern.
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Lowest price we've seen: $128.06 on Nov 10 at StyleVana. Tracked across 18 stores since Nov 10.
Owners generally describe a light, non-sticky serum that layers cleanly and causes little irritation, even on sensitive skin. Those who stick with it report softer, smoother-looking lines around the eyes and forehead, while others say the change is subtle and takes months.
Pair a nourishing serum with your existing skincare favorites to maximize benefits for your skin. This serum & face oil is suitable for oily skin.
