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Super Skinny is a once-weekly injectable that combines tirzepatide, a dual GLP-1 and GIP receptor agonist, with glycine and vitamin B12 (cyanocobalamin). It is marketed for weight loss, especially for people who have plateaued on semaglutide or had side effects with it. The dual-receptor action sets it apart from single-receptor GLP-1 drugs like semaglutide. Tirzepatide is the same active ingredient as in Eli Lilly's Zepbound and Mounjaro, but Super Skinny is a compounded formulation that adds glycine and B12. No large clinical trials of this specific combination have been published, so its added benefits are not proven.
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Super Skinny is a once-weekly injectable that combines tirzepatide with vitamin B12 (cyanocobalamin). Tirzepatide is a dual agonist of the GLP-1 and GIP receptors. It increases insulin production, lowers glucagon secretion and acts on areas of the brain that regulate appetite and food intake. A small change to the molecule lets it last for weeks in the body, while the natural version lasts minutes. B12 is included as an essential vitamin that supports energy and absorption.
The 1 mL vial equals 100 units. A typical starting dose is 25 units weekly, and 1 mL should last 4 weeks.
This is a patient-specific compounded medication, made in an FDA-licensed compounding facility from a prescription by a licensed healthcare professional. Compounded drugs use ingredients from FDA-licensed facilities, and sterile compounds are tested for potency, sterility and purity. They do not go through FDA pre-market approval, so the dose, route of administration and efficacy may differ from brand-name drugs.