How is Zenrelia different from Apoquel?

Both are daily oral JAK inhibitors for allergic itch, but they use different active ingredients, ilunocitinib versus oclacitinib. Zenrelia is a newer option, so a dog that did poorly on Apoquel may still respond to it.

How is it different from Cytopoint?

Cytopoint is a monthly injection given at the vet; Zenrelia is a daily tablet given at home. Cytopoint has no vaccination-timing restriction, while Zenrelia does.

How fast does it work?

Owners commonly report less scratching within the first days of daily dosing, with continued improvement over the following weeks.

Can it be given with food?

Yes. The chewable tablet can be given with or without food, once daily.

Can my dog get vaccinated while taking it?

Stop Zenrelia at least 28 days to 3 months before vaccination and do not restart for at least 28 days after. Plan the schedule with your veterinarian.

30 tablets of 4.8 mg ilunocitinib, a 30-day supply at the once-daily dose.

What do buyers say about the Zenrelia (Ilunocitinib) Tablets 4.8 mg, 30 Count?

Rated 4.6 out of 5 from 1,100 ratings.

Where can I buy the Zenrelia (Ilunocitinib) Tablets 4.8 mg, 30 Count?

5 stores we checked sell it, including Amazon, Chewy.com, Allivet Pet Pharmacy, Petco.com, PetMeds.

Zenrelia (Ilunocitinib) Tablets 4.8 mg, 30 Count

Q: Where is the Zenrelia (Ilunocitinib) Tablets 4.8 mg, 30 Count cheapest?

At Allivet Pet Pharmacy, for $61.79, 27% under what the other stores charge, as of our latest check.

Best price now

$61.79at Allivet Pet PharmacyChecked 1 h ago

27% under what the other stores charge

Compared across 5 stores. Prices are checked against each store and labelled with when.

Visit Allivet Pet Pharmacy

What reviewers say

4.6 / 51,100 ratings

Owners report fast, marked relief from scratching and skin irritation, often within days, and many say their dogs tolerate the chewable tablet well. Some note the vaccination timing rule complicates their schedule, and a few saw limited benefit or needed a vet to adjust the plan.

What people mention

Itch reliefPraisedOwners say scratching and skin irritation drop noticeably, often within the first week.
DosingPraisedThe once-daily chewable tablet is easy to give, with or without food.
Vaccination timingCriticisedOwners find the stop-before and wait-after vaccination rule hard to fit around their dog's schedule.
ResponseMixedMany dogs improve, but some owners report little change and need a vet to rethink the plan.
Long-term usePraisedOwners on months of treatment say flare-ups stay controlled.

About the Zenrelia (Ilunocitinib) Tablets 4.8 mg, 30 Count

Zenrelia (ilunocitinib tablets) is a prescription itch relief medication for dogs. It relieves itching due to allergic dermatitis and controls atopic dermatitis. The active ingredient, ilunocitinib, reduces the inflammatory response in the skin caused by allergies, so dogs feel less itchy.

Zenrelia is designed to deliver continuous efficacy over the long term. It works fast, with visible improvements in itch. Clinical remission of itch was demonstrated by a Normal-PVAS score below 2.

It is a once-daily tablet that can be given at home with or without food. It is for dogs 12 months and older, and your veterinarian sets the dose.

Active ingredient

Ilunocitinib

Strength

4.8 mg per tablet

Count

30 tablets

Animal

Dog

Age

Dogs 12 months and older

Use