What does Simparica Trio protect against?

It prevents heartworm disease, kills fleas and five types of ticks, and treats roundworms and hookworms. It does not cover tapeworms or mites.

How often is it given?

One chew once a month. It can be given with or without food.

Is it safe for puppies?

It is labeled for puppies from 8 weeks old, within the correct weight band. Ask your vet before starting any puppy on it.

Do I need a prescription?

Yes. A veterinarian must prescribe it, and most vets want a negative heartworm test before starting.

How does it compare with separate heartworm and flea products?

It folds heartworm prevention, flea and tick control and deworming into one monthly chew, so you skip stacking two or three products. The trade-off is that it does not add tapeworm or mite coverage.

What if my dog spits out the chew?

You can offer it with food or crush it into a meal, but do not split the dose unless your vet advises it. If a dose is missed or vomited soon after, call your vet.

Zoetis Simparica Trio Chewable Tablets for Dogs 44.1-88 lbs (6-month supply)

Q: Where is the Zoetis Simparica Trio Chewable Tablets for Dogs 44.1-88 lbs (6-month supply) cheapest?

At ShotVet, for $209.00, as of our latest check.

Q: Where can I buy the Zoetis Simparica Trio Chewable Tablets for Dogs 44.1-88 lbs (6-month supply)?

9 stores we checked sell it, including ShotVet, PetSmart, Amazon, Tractor Supply Co, Chewy.

Best price now

$209.00at ShotVetChecked 15 h ago

Compared across 8 stores. Prices are checked against each store and labelled with when.

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What reviewers say

Owners generally report that Simparica Trio is easy to give and that their dogs take the chew without a fight. Many say it replaced two or three separate products and that flea and tick control held up well through the season. A minority report stomach upset, vomiting or lethargy in the day or two after dosing.

What people mention

ConveniencePraisedOwners like replacing multiple monthly products with one chew.
PalatabilityPraisedMost dogs take the liver-flavored chew as a treat, though some refuse it.
Stomach upsetCriticisedSome owners report vomiting or loose stool after a dose.
Flea and tick controlPraisedOwners report good results against fleas and ticks through the season.
LethargyMixedA few owners say their dog was tired or off food for a day after dosing.

About the Zoetis Simparica Trio Chewable Tablets for Dogs 44.1-88 lbs (6-month supply)

Simparica Trio is a monthly chewable tablet for dogs. It protects against heartworm disease, five types of ticks, fleas, roundworms and hookworms.

The dose is chosen by the dog's weight. Dogs weighing 44.1-88 lbs get one tablet per month, containing 48 mg sarolaner, 0.96 mg moxidectin and 200 mg pyrantel. It can be given with or without food. This pack is a 6-month supply.

Simparica Trio has been shown to be safe for puppies as young as 8 weeks old. A veterinarian's prescription is required.

Animal

Dog

Dog weight

44.1-88 lbs

Form

Chewable tablet

Dosing

One tablet once a month, with or without food

Active ingredients

48 mg sarolaner, 0.96 mg moxidectin, 200 mg pyrantel per tablet

Protects against