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Best flea and tick treatments for dogs under 40 lb

Researched by Deal.ai's shopping agent across stores on November 4, 2026. Prices below are today's.

Top pick: K9 Advantix II, 6-month pack for small dogs (4–10 lb). It's the strongest protection in a multi-dose pack here — fleas, ticks and mosquitoes, repels as well as kills — and buying six months at once is the best value per dose of the vet-style options.

Who the others suit:

  • TevraPet Activate II, 4 doses (4–10 lb): budget spot-on for a small dog; same idea, fewer extras.
  • Hartz UltraGuard, 3 doses (5–14 lb or 15–30 lb): cheapest way to try a topical; pick the size band that matches your dog.
  • K9 Advantix II, 2 doses (11–20 lb): for a dog in that band who only needs a short stretch.
  • Seresto collar (up to 18 lb): not a multi-dose pack, but one collar covers 8 months — best if you'd rather not dose monthly.

Match the weight band to your dog; a 30–40 lb dog needs the next size up.

The picks

  1. K9 Advantix II
    K9 Advantix II Monthly Flea & Tick Prevention for Small Dogs 4-10 lbs, 6-Monthly Treatment
    #1

    K9 Advantix II Monthly Flea & Tick Prevention for Small Dogs 4-10 lbs, 6-Monthly Treatment

    • multipack_quantity: 1
    • count_per_pack: 6
    • color: White
    • size: 4-10lb
    $37.95at eBayVerifiedPrices and history →
  2. TevraPet
    TevraPet Activate II Fast Acting Alcohol-Free Flea & Tick Prevention Topical for Small Dogs, 4-10 lbs, 4 Doses
    #2

    TevraPet Activate II Fast Acting Alcohol-Free Flea & Tick Prevention Topical for Small Dogs, 4-10 lbs, 4 Doses

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  • size: Small 4-10 lbs
  • pet_size: Small
  • color: Multicolor
$18.99at eBayVerifiedCompare 2 stores →
  • ULTRA
    Hartz UltraGuard Dual Action Flea & Tick Topical for Small Dogs 5-14lbs, 3 Monthly Treatments
    #3

    Hartz UltraGuard Dual Action Flea & Tick Topical for Small Dogs 5-14lbs, 3 Monthly Treatments

    • shape: 3 count
    • size: 5-14lbs
    • multipack_quantity: 1
    • count_per_pack: 3
    • color: Multicolor
    $12.28at eBayVerifiedCompare 2 stores →
  • Hartz
    Hartz UltraGuard Dual Action Flea & Tick Topical for Medium Dogs 15-30lbs, 3 Monthly Treatments
    #4

    Hartz UltraGuard Dual Action Flea & Tick Topical for Medium Dogs 15-30lbs, 3 Monthly Treatments

    • number_of_pieces: 3
    • size: 15-30lbs
    • shape: 3 count
    • multipack_quantity: 1
    • count_per_pack: 3
    • color: Multicolor
    $6.52at Chewy.comObserved at 5:34 AMCompare 2 stores →
  • K9 Advantix II
    K9 Advantix Flea, Tick & Mosquito Prevention for Medium Dogs 11-20 lbs., 2-Monthly Treatments
    #5

    K9 Advantix Flea, Tick & Mosquito Prevention for Medium Dogs 11-20 lbs., 2-Monthly Treatments

    • multipack_quantity: 1
    • pet_size: Medium
    • color: White
    • size: M
    Prices and history →
  • Seresto
    Seresto Flea & Tick Collar For Dogs Up to 18 lbs., Vet-Recommended, 8 Month Protection
    #6

    Seresto Flea & Tick Collar For Dogs Up to 18 lbs., Vet-Recommended, 8 Month Protection

    • number_of_pieces: 1
    • multipack_quantity: 1
    • theme: Dogs up to 18 lbs, 15-inch Collar
    • count_per_pack: 1
    • color: White
    • size: 1
    Prices and history →