Which is better for gaming?

The MSI GF65. Its GTX 1660 Ti is a clear step above the GTX 1650, so it holds higher frame rates at the same settings. The Nitro 5's 144Hz screen only helps if the GPU can push those frames.

Which has the better screen?

The Nitro 5 for fast games, thanks to its 144Hz refresh rate. The GF65's panel is standard refresh, so motion looks less smooth in shooters.

The GF65 has the sturdier aluminum build and better cooling design. The Nitro 5 is plastic but easier to service, which can extend its life through upgrades.

Is the GF65 worth stepping up to?

Yes for most buyers. The i7 and GTX 1660 Ti give noticeably better gaming and multitasking performance, and owners rate it highly.

Can I upgrade either laptop?

The Nitro 5 is the easier one. It has accessible RAM slots and room for more storage. The GF65 is more closed off inside.

Which is more portable?

The GF65. It is thinner and lighter with a brushed aluminum lid. The Nitro 5 is a chunkier plastic machine at about 5.1 lb.

Acer Nitro 5 AN515-55 Gaming Laptop vs MSI GF65 Thin Gaming Laptop

The MSI GF65 is the stronger pick for most gamers. Its i7 processor and GTX 1660 Ti beat the Nitro 5's i5 and GTX 1650 in games and multitasking, and owners rate it 4.7 out of 5. The Nitro 5 is the budget-minded alternative with a 144Hz screen and easy RAM and storage upgrades, but its weaker GPU and 8GB base RAM hold it back.

Choose the Acer Nitro 5 if you want a 144Hz display and plan to add your own RAM and storage later.
Choose the MSI GF65 if you want more gaming performance out of the box and a lighter, slimmer chassis.

Prices

Acer Nitro 5 AN515-55 Gaming Laptop: $589.00 at KenDoTronics (last seen Nov 13)
MSI GF65 Thin Gaming Laptop: $729.99 at eBay (last seen Nov 10)
Difference: the Acer Nitro 5 AN515-55 Gaming Laptop is $140.99 cheaper than the MSI GF65 Thin Gaming Laptop at the latest prices (Nov 10 and Nov 13)