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Dr.Melaxin Cemenrete Cyano Pink Spicule Serum vs La Roche-Posay Pure Vitamin C12 Serum

Buy the La Roche-Posay Pure Vitamin C12 if you want a well-known brightening vitamin C serum for daytime use and sensitive skin. Buy the Dr.Melaxin Cemenrete set if you want a two-bottle supply of a spicule serum aimed at tightening and under-eye use. The La Roche-Posay is $40.50 at StyleVana as of November 7, 2026, and its lowest recent daily price was $17.95 on November 6, 2026. The Dr.Melaxin set has no price given here, so compare its per-bottle cost against that $40.50 before deciding.

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Dr.Melaxin
Dr.Melaxin Cemenrete Cyano Pink Spicule Serum 30ml 2-Piece Set

Dr.Melaxin Cemenrete Cyano Pink Spicule Serum

Dr.Melaxin Cemenrete Cyano Pink Spicule Serum 30ml 2-Piece Set

4.5(457 ratings)
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Choose the Dr.Melaxin Cemenrete set if you want two 30ml bottles of a fragrance-free spicule serum for tightening and under-eye use, and you prefer vitamin B12 and niacinamide over vitamin C.

Pros
  • Two 30ml bottles in one set
  • Spicules give a physical exfoliating and tightening effect
  • Niacinamide plus vitamin B12 formula
  • Free of synthetic fragrances and listed for sensitive skin
  • Can be used day and night, including under the eyes
Cons
  • No price given here, so value is hard to judge
  • Spicules can sting or irritate first-time users
  • No vitamin C for brightening
  • Not for babies or kids
  • Tightening effect is the main claim, not tone correction
La Roche-Posay
La Roche-Posay Pure Vitamin C12 Serum

La Roche-Posay Pure Vitamin C12 Serum

$40.50at StyleVanaObserved at 1:51 PM
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Visit StyleVana

Store links may earn us a commission. Price via Klarna.

Choose the La Roche-Posay Pure Vitamin C12 if you want a 12% pure vitamin C serum with salicylic acid and neurosensine for daytime brightening, and you have sensitive skin.

Pros
  • 12% pure vitamin C for brightening and photoaging defense
  • Salicylic acid smooths texture and unclogs pores
  • Neurosensine and thermal water soothe sensitive skin
  • Lightweight, non-greasy, fragrance-free and non-comedogenic
  • Large review base: 4.4 out of 5 from 5,891 Google Shopping ratings
Cons
  • Some shoppers report dirty, clogged or crystallized droppers and packaging
  • Only one 1 oz bottle per purchase
  • Daytime use only per the listing
  • Vitamin C can be unstable once opened
  • Price swung from $17.95 to $40.50 within two days

What separates them

Dr.Melaxin Cemenrete Cyano Pink Spicule SerumLa Roche-Posay Pure Vitamin C12 Serum
Main activeVitamin B12 (pink vitamin), spicules, niacinamide12% pure vitamin C, salicylic acid, neurosensine
Primary effectTighteningBrightening and radiance
SpiculesYes, physically stimulates skinNo
Use timeDay and nightDay, morning
Size per unit30ml, two bottles in the set1 oz (about 30ml), one bottle
TextureNot statedLightweight, non-greasy, silky
FragranceFree of synthetic fragrancesFragrance-free
PriceNot given$40.50 at StyleVana as of November 7, 2026

Price history

$44.98$17.95
Nov 2Nov 7
  • Dr.Melaxin Cemenrete Cyano Pink Spicule Serum: lowest $44.98 on Nov 2 at YesStyle.com.
  • La Roche-Posay Pure Vitamin C12 Serum: lowest $17.95 on Nov 6 at eBay; $40.50 on Nov 7.

Prices at every store

Dr.Melaxin Cemenrete Cyano Pink Spicule Serum

  • YesStyle.comCheck price at YesStyle.com
Prices and history →

La Roche-Posay Pure Vitamin C12 Serum

  • StyleVanaNew

    In stock

    $40.50Free shippingObserved at 1:51 PM
    Visit StyleVana

Also available at

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Prices and history →

Specs compared

SpecDr.Melaxin Cemenrete Cyano Pink Spicule SerumLa Roche-Posay Pure Vitamin C12 Serum
Body PartFaceFace
FormSerumSerum
Skin ConcernsWrinklesWrinkles
Skin TypeAll Skin TypesSensitive skin
Active IngredientsNiacinamideSalicylic acid, Neurosensine
Key IngredientVitamin B12, Spicules, Pink vitamin (Vitamin B1…Vitamin C
SubtypeHydrating serumHydrating serum
TypeSerumSerum
Face Treatment TypeSerumSerum
ContainsWater, Glycerin, Niacinamide, SpiculesSalicylic acid, Neurosensine, Vitamin C
Free OfSynthetic fragrancesFragrance-free
For BabiesNoNo
Show all 33 specsShow fewer specs
SpecDr.Melaxin Cemenrete Cyano Pink Spicule SerumLa Roche-Posay Pure Vitamin C12 Serum
For KidsNoNo
For MenNoYes
EffectTighteningRadiance
Size30ml1 oz.
Night / Day UseBothDay
Tattoo CareNoNo
Use HighlightsUnder EyeUnder Eye
Application MethodGently stimulate skin regeneration (with spicul…—
Tint ColorPink—
Suitable For

What reviewers say

Dr.Melaxin Cemenrete Cyano Pink Spicule Serum

  • 4.5 / 5457 ratings

Rated 4.5 out of 5 from 457 ratings, buyers generally rate it highly. The spicule tingle is the most divisive part of the experience.

What people mention
  • Spicule feelMixedBuyers describe a prickly, tingling sensation when the spicules go on.
  • HydrationPraisedUsers say skin feels moisturized after applying it.
  • FragrancePraisedThe fragrance-free formula is welcomed by sensitive-skin users.
  • FirmnessMixedSome report tighter, firmer skin; others see little change in wrinkles.

La Roche-Posay Pure Vitamin C12 Serum

  • 4.4 / 5Google Shopping · 5,891 ratings

Shoppers are split. Many praise the glow, smoothness and thick, easy-to-spread texture, while a notable share complain about the dropper and packaging, with some finding dirty, clogged or crystallised product.

What people mention
  • GlowPraisedUsers say skin looks brighter and healthier after regular use.
  • TexturePraisedThe thick serum spreads easily across the face and neck.
  • PackagingCriticisedReviewers call the bottle and dropper poor quality.

Questions and answers

Which is better for sensitive skin?
Both are listed as suitable for sensitive skin and fragrance-free. The La Roche-Posay adds neurosensine and thermal water to calm skin, while the Dr.Melaxin spicules can cause mild stinging on first use.
Which one brightens skin tone?
The La Roche-Posay, which has 12% pure vitamin C plus salicylic acid for radiance and even tone. The Dr.Melaxin focuses on tightening, not brightening.
Can I use the Dr.Melaxin serum at night?
Yes. It is listed for both day and night use. The La Roche-Posay is listed for morning use only.
Is the La Roche-Posay worth $40.50?
It was $17.95 on November 6, 2026, so $40.50 is well above its recent low. If you can wait for a dip, the same bottle costs much less.
How long does each last?
Both are about 30ml. At one pump or dropper per day, each bottle lasts roughly one to two months. The Dr.Melaxin set gives you two bottles, so about twice as long.
Which is better under the eyes?
Both list under-eye use. The Dr.Melaxin's spicules and tightening claim suit puffiness and firmness, while the La Roche-Posay's vitamin C suits dark circles and dullness.

More comparisons

  • La Roche-Posay Pure Vitamin C12 Serum vs e.l.f. Skin Bright Icon Vitamin C + E + Ferulic Serum
  • La Roche Posay Retinol B3 vs Dr.Melaxin Cemenrete Cyano Pink Spicule Serum 30ml 2-Piece Set
  • Skin Deva Vitamin B5 + Hyaluronic Acid Serum vs La Roche-Posay Pure Vitamin C12 Serum

Buying guides that pick them

  • Best vitamin C serums for face
Sensitive Skin
—
Age RangeAdult—
Fragrance-free—yes
Application Time—Daily, Morning
Overnight Use—No
Texture—Lightweight, Non-greasy, Silky
Weight (oz)—1.01
Content—Hyaluronic Acid, Antioxidants, Peptides, Salicy…
Packaging—Pipette
Skin Concern—Wrinkles
Gender—Unisex
Volume (fl oz)—1.0
  • DropperCriticisedSome droppers arrive dirty, clogged or full of residue.