Nutri-Vet Guard Plus Flea & Tick Treatment for Dogs vs Sentry Fiproguard Flea & Tick
Both are fipronil spot-ons, but they fit different dogs. Nutri-Vet Guard Plus adds methoprene, an insect growth regulator that stops flea eggs and larvae from developing, and it is dosed for large dogs at 89-132 lbs. Sentry Fiproguard is plain fipronil for dogs at 23-44 lbs. The Sentry is the cheaper buy at $17.99 at Chewy.com as of November 4, 2026; no current price was given for the Nutri-Vet. Buy the Nutri-Vet for a large dog if you want flea lifecycle control; buy the Sentry for a mid-size dog on a budget.
Ask our shopping agent
Nutri-Vet Guard Plus Flea & Tick Treatment for Dogs
4.3Choose the Nutri-Vet Guard Plus if you have a dog in the 89-132 lb range and want an IGR in the formula to break the flea life cycle, not just kill adult fleas.
- Adds an insect growth regulator, so it also hits flea eggs and larvae
- Labeled for dogs 8 weeks and older
- Cleared for breeding, pregnant and lactating females
- Higher rating, though from far fewer ratings
- Covers chewing lice as well as fleas and ticks
- Only sized for dogs 89-132 lbs
- No current price available to compare
What separates them
| Nutri-Vet Guard Plus Flea & Tick Treatment for Dogs | Sentry Fiproguard Flea & Tick | |
|---|---|---|
| Active ingredients | Fipronil 9.8% plus (S)-methoprene 11.8% (an IGR) | Fipronil 9.7% only |
| Flea lifecycle coverage | Kills adult fleas and stops eggs and larvae from developing | Targets adult fleas only |
| Dog weight range | 89-132 lbs (large breeds) | 23-44 lbs |
| Minimum age | Dogs 8 weeks and older | Adult dogs |
| Waterproof | Not stated | Waterproof |
| Supply per pack | 3-pack, monthly dosing, up to about six weeks of residual | 3-month supply, up to 30 days per dose |
| Rating | 4.3 out of 5 from 40 ratings | 3.8 out of 5 from 898 ratings |
Price history
- Nutri-Vet Guard Plus Flea & Tick Treatment for Dogs: lowest $14.26 on Nov 4 at Chewy.com.
- Sentry Fiproguard Flea & Tick: lowest $14.99 on Nov 4 at Cherrybrook.
Prices at every store
Nutri-Vet Guard Plus Flea & Tick Treatment for Dogs
- Pet LifeNew
Out of stock
$25.98+ $9.95 shippingObserved at 5:12 AM
Also available at
- Academy Sports + OutdoorsCheck price at Academy Sports + Outdoors
- AmazonCheck price at Amazon
- Armor Animal HealthCheck price at Armor Animal Health
Sentry Fiproguard Flea & Tick
- Chewy.comNew
In stock
$17.99Observed at 5:11 AM - Petco.comNew
In stock
$17.99Observed at 5:11 AM
Also available at
- AmazonCheck price at Amazon
- WalmartCheck price at Walmart
- Pet GoodsCheck price at Pet Goods
Specs compared
| Spec | Nutri-Vet Guard Plus Flea & Tick Treatment for Dogs | Sentry Fiproguard Flea & Tick |
|---|---|---|
| Targeted Pests | Chewing lice, Fleas, Ticks | Fleas, Ticks |
| Active Ingredient | (S) Methoprene, Fipronil | Fipronil |
| Administration Method | Topical | Topical solution, Spot-on |
| Formulation Type | Topical | Topical Solution, Spot-on |
| Life Stage Age | dogs 8 weeks and older | Adult |
| Treatment Frequency | Monthly | Monthly |
| Dosage Concentration | (S) Methoprene 11.8%, Fipronil 9.8% | 9.70% (fipronil) |
| Dosage Duration | up to a month, six weeks | Up to 30 days |
| Lifecycle Targeted | fleas | Adult fleas |
What reviewers say
Nutri-Vet Guard Plus Flea & Tick Treatment for Dogs
Ratings sit around 4.3 out of 5 from about 40 buyers, which suggests most owners find it works as a routine monthly preventive. Complaints tend to center on application mess and on fleas that keep coming back in heavy-infestation homes.
- Easy monthly application
- Works as a preventive for fleas and ticks
- Good value for a 3-pack
- Oily residue at the application site
- Mixed results where fleas are already established
- Sizing limited to large dogs
Sentry Fiproguard Flea & Tick
Ratings average 3.8 out of 5 from 898 reviews. Many owners say it controls fleas at a low price, while others report irritation or that fleas kept coming back.
- Noticeably cheaper than vet brands
Questions and answers
- Which is better for a large dog?
- The Nutri-Vet Guard Plus. It is dosed for dogs 89-132 lbs, while Sentry Fiproguard tops out at 44 lbs.
- Does the Sentry kill flea eggs?
- No. It contains fipronil only, which targets adult fleas. The Nutri-Vet adds methoprene, an IGR that stops eggs and larvae from developing.
- Is the Sentry worth the lower price?
- At $17.99 at Chewy.com as of November 4, 2026, it is the cheaper option and covers a 3-month supply. You give up egg and larval control and the large-dog weight range.
- Can I use either on a pregnant dog?
- Both list pregnant, breeding and lactating dogs as suitable. The Nutri-Vet also states a minimum age of 8 weeks; the Sentry is labeled for adult dogs.
- Which lasts longer per dose?
- The Nutri-Vet states up to a month, up to six weeks. The Sentry states up to 30 days. Both are dosed monthly.
- Is the Sentry safe around cats?
- No. The label warns not to use it on cats. Keep treated dogs away from cats until the spot-on dries.