Simparica Chewable Tablets for Dogs vs Nutri-Vet Guard Plus Flea & Tick for Dogs

Simparica is the stronger choice for most dogs: a prescription oral chew with sarolaner that starts killing fleas in about 3 hours and ticks in about 8, with a full month of protection per dose. Nutri-Vet Guard Plus is a topical fipronil and methoprene product that also kills flea eggs and larvae, so it breaks the flea life cycle, and it is cleared for puppies from 8 weeks and for pregnant or nursing bitches. Simparica has far more owner feedback and a higher rating, and dogs generally take the chew without a fight; Guard Plus suits owners who prefer a spot-on or need the younger-age and breeding-safety label.

• Choose the Simparica if your dog is at least 6 months old and 2.8 lb, you have a vet prescription, and you want fast flea and tick kill in an easy chew.
• Choose the Nutri-Vet Guard Plus if you want a non-prescription topical that also kills flea eggs and larvae, or your dog is 8 weeks to 6 months old or a pregnant or nursing female.