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Seresto Flea & Tick Collar for Dogs vs NexGard Chewables for Small Dogs

Seresto is the better pick for most owners who want set-and-forget protection: one collar lasts 8 months, works on dogs over 18 lbs, and is the vet-recommended collar with a long track record. NexGard is the stronger choice for small dogs (10.1–24 lbs) and for owners who prefer an oral chew and want fast flea kill and broad tick coverage. NexGard's 4.8 rating comes from far fewer reviewers than Seresto's 4.4 from nearly 9,000, so weigh the larger sample accordingly.

  • Choose the Seresto collar if you want 8 months of flea and tick protection from one application and don't want to remember a monthly dose.
  • Choose the NexGard chew if your dog is 10.1–24 lbs and you prefer a beef-flavored oral chew with fast flea kill and broad tick coverage.

Prices

  • Seresto Flea & Tick Collar for Dogs: $107.99 at Petsmart (checked today)
  • NexGard Chewables for Small Dogs: $78.00 at Smartway Pet Supplies (checked today)
  • Difference: the NexGard Chewables for Small Dogs is $29.99 cheaper than the Seresto Flea & Tick Collar for Dogs today
Seresto
Seresto Flea & Tick Collar For Dogs & Puppies Over 18 lbs., 8-Month Protection (2 Count)

Seresto Flea & Tick Collar for Dogs

Seresto Flea & Tick Collar For Dogs & Puppies Over 18 lbs., 8-Month Protection (2 Count)

4.4(8,922 ratings)
$107.99at PetsmartChecked 2 h ago
See all prices and details
Visit Petsmart

Store links may earn us a commission. Price via Klarna.

Pros
  • 8 months of protection from a single collar
  • Vet-recommended flea and tick collar
  • Odorless and non-greasy
  • Works for dogs over 18 lbs and puppies from 7 weeks
  • Large review base backs real-world results
Cons
  • Collar must stay on the dog continuously
  • Not sized for dogs under 18 lbs
  • Some dogs may be sensitive to the collar
  • Slower flea kill than an oral chew
NexGard
NexGard Chewables for Small Dogs 10.1–24 lbs (4.1–10 kg)

NexGard Chewables for Small Dogs

NexGard Chewables for Small Dogs 10.1–24 lbs (4.1–10 kg)

4.8(40 ratings)
$78.00at Smartway Pet SuppliesChecked 4 h ago
See all prices and details
Visit Smartway Pet Supplies
Pros
  • Fast flea kill: 100% within 8 hours
  • Covers four common tick species
  • Beef-flavored soft chew most dogs take as a treat
  • No mess, no residue; swim and bathe right after dosing
  • Dosed precisely for small dogs 10.1–24 lbs
Cons
  • Monthly dosing to remember
  • Only for dogs 10.1–24 lbs
  • Small review base of 40 ratings
  • Some dogs may refuse the chew or have stomach upset

What separates them

Seresto Flea & Tick Collar for DogsNexGard Chewables for Small Dogs
FormPlastic collar worn continuouslySoft beef-flavored chew given orally
Dosing frequencyOne collar per 8 monthsOne chew per month
Dog size rangeDogs over 18 lbsSmall dogs 10.1–24 lbs
Minimum age7 weeks8 weeks
Flea kill speedKills and repels over time via skin and coatStarts killing fleas within 4 hours, 100% within 8 hours
Tick coverageKills and repels ticksControls deer, American dog, lone star and brown dog ticks
Water and handlingCollar stays on; odorless and non-greasyBathe, swim and pet right after dosing
Review base4.4 from 8,922 ratings4.8 from 40 ratings

Price history

  • Seresto Flea & Tick Collar for Dogs: lowest $107.99 on Nov 11 at Petsmart.
  • NexGard Chewables for Small Dogs: lowest $81.95 on Nov 11 at Joes Pet Meds.

Prices at every store

Seresto Flea & Tick Collar for Dogs

  • PetsmartNew

    In stock

    $107.99+ $5.99 shippingChecked 2 h ago
    Visit Petsmart
  • WalmartNew

    In stock

    $115.97Free shippingChecked 2 h ago
    Visit Walmart
  • Tractor Supply CoNew

    Availability unknown

    $115.99Free shippingChecked 2 h ago
    Visit Tractor Supply Co

Store links may earn us a commission. Some prices via Klarna.

All 3 stores and price history →

NexGard Chewables for Small Dogs

  • Smartway Pet SuppliesNew

    In stockShips from Australia · duties may applyReturn policy

    $78.00Checked 4 h ago
    Visit Smartway Pet Supplies
  • Tractor Supply CompanyNew

    In stock

    $91.39Checked 4 h ago
    Visit Tractor Supply Company
  • Joes Pet MedsNew

    Availability unknownShips from abroad · duties may apply

    $81.95Checked 4 h ago
    Visit Joes Pet Meds
  • PetSmartNew

    Availability unknown

    $91.39Checked 4 h ago
    Visit PetSmart
All 13 stores and price history →

Specs compared

SpecSeresto Flea & Tick Collar for DogsNexGard Chewables for Small Dogs
number_of_pieces2—
multipack_quantity1—
animal_typeLarge Dog—
count_per_pack2—
colorWhite—
size2 Pack—
No. of Packs (pack)2—
MaterialPlastic—
Weight (lb)0.4—
Animal—Dog
active ingredient—afoxolaner
target weight—10.1 to 24.0 lbs.
Show all 21 specsShow fewer specs
SpecSeresto Flea & Tick Collar for DogsNexGard Chewables for Small Dogs
afoxolaner per chewable—28.3 mg
flavor—beef-flavored
form—soft chewables
minimum age—8 weeks of age and older
dosage frequency—once a month
minimum dosage—1.14 mg/lb (2.5 mg/kg)
protection duration—one month
administration route—oral
chemical composition—1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(tri…

What reviewers say

Seresto Flea & Tick Collar for Dogs

  • 4.4 / 58,922 ratings

Owners and reviewers largely rate Seresto highly for convenience and long-lasting flea and tick control, and many say it replaced monthly treatments. A minority report skin irritation, hair loss at the neck, or reduced effectiveness toward the end of the 8 months.

What people mention
  • DurationPraisedOwners like getting months of protection from one collar instead of monthly applications.
  • Skin irritationCriticisedSome owners report redness, itching or hair loss around the neck where the collar sits.
  • Water resistancePraisedReviewers say it keeps working after swimming and baths.
  • EfficacyMixedMany see fewer fleas and ticks, but some report pests returning before the 8 months are up.

NexGard Chewables for Small Dogs

  • 4.8 / 540 ratings

Owners rate NexGard highly, with 4.8 out of 5 from 40 ratings. Most praise how quickly it clears fleas and how easily dogs accept the chew. A minority report vomiting or refusal.

What people mention
  • Flea killPraisedOwners say fleas are gone within hours to a day of the first chew.
  • PalatabilityMixedMost dogs eat it like a treat, but some owners say their dog spits it out or needs it hidden in food.
  • Stomach upsetCriticisedA minority report vomiting or loose stool after dosing.
  • Tick coveragePraised

Questions and answers

Which is better for a small dog under 18 lbs?
NexGard. Seresto's collar is labeled for dogs over 18 lbs, while NexGard Blue is dosed for 10.1–24 lbs.
Which lasts longer?
Seresto. One collar covers 8 months. NexGard is a monthly chew, so you dose 8 times over the same period.
Which kills fleas faster?
NexGard. It starts working within 4 hours and kills 100% of fleas within 8 hours of dosing. Seresto works gradually through the skin and coat.
Is NexGard worth stepping up to over Seresto?
If your dog is in the 10.1–24 lb range and you want fast flea kill and broad tick coverage, yes. If you want to dose once and forget it, Seresto is simpler.
Can I use Seresto on a puppy?
Yes, for puppies 7 weeks and older that weigh over 18 lbs. NexGard is labeled for puppies 8 weeks and older within its weight range.
Do either need a vet prescription?
No. Both are sold without a prescription, though it's worth confirming the choice with your vet for dogs with health issues.

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More comparisons

  • Seresto Flea & Tick Collar For Dogs & Puppies Over 18 lbs., 8-Month Protection (2 Count) vs Vet's Best Topical Flea & Tick Treatment for Dogs
  • Vet's Best Topical Flea & Tick Treatment for Dogs vs NexGard Chewables for Small Dogs 10.1–24 lbs (4.1–10 kg)

Buying guides that pick them

  • Best flea and tick treatments for dogs under 40 lb
Owners report fewer ticks, including deer ticks, on treated dogs.