Is the TD-2350D300 a direct thermal or thermal transfer printer?

It is direct thermal only. It prints on heat-sensitive label stock and uses no ribbon, so there is no thermal transfer mode for resin or wax ribbons.

Can it replace a Zebra printer without changing my labels?

It supports ZPL II and ZPL emulation, plus EPL2, DPL, CPCL and ESC/P. Many existing label files can run with little or no change, though you should test your templates first.

What label sizes does it take?

It handles labels up to 2.48 inches wide and prints up to 2.32 inches wide, with a maximum print length of about 118 inches. That fits most barcode, shelf and specimen labels but not wide shipping labels.

It offers Ethernet, dual-band Wi-Fi, Bluetooth 5.2, USB, USB host and serial. That covers shared network use, direct PC connection and printing from iOS or Android devices.

Does it cut or peel labels?

It has a peel facility for removing labels one at a time. Check the specific configuration for a cutter if you need full cutting.

Will the printed labels last?

Direct thermal print fades when exposed to heat, sunlight or friction over time. For labels that must last years, use a thermal transfer printer instead.