Black FridayDealsBuying guidesBrandsStoresTermsPrivacydeal.ai apps

© Deal.ai Inc.

Deal.ai
Comfortis
Comfortis 270mg for Cats 6.1-12 lbs and Dogs 10-20 lbs, 6 Pack

Comfortis 270mg for Cats 6.1-12 lbs and Dogs 10-20 lbs, 6 Pack

4.6· 14 ratings

Best price now

$124.69at California Pet PharmacyObserved at 3:44 PM

Prices are checked against each store and labelled with when.

Visit California Pet Pharmacy

Ask our agent about this product

It checks today's price at every store, compares the alternatives and answers in about a minute.

Enter to send, Shift+Enter for a new line

Our take on the Comfortis 270mg for Cats 6.1-12 lbs and Dogs 10-20 lbs, 6 Pack

Comfortis is a beef-flavored chewable flea tablet with spinosad as its active ingredient. It starts killing fleas within 30 minutes and kills adult fleas before they can lay eggs, given once a month. This 6-pack is a six-month supply. The best new price is $124.69 at California Pet Pharmacy as of November 4, 2026, and only one store lists it new, so there is no lower price to compare against.

Best forCat owners with pets in the 6.1-12 lb rangeDog owners with pets in the 10-20 lb rangeOwners who prefer an oral tablet over topical dropsHouseholds treating an active flea infestation
Pros
  • Starts killing fleas within 30 minutes
  • Kills adult fleas before they can lay eggs
  • Beef-flavored chewable is easy to give
  • Monthly dosing, six tablets per box
  • Approved for kittens and puppies 14 weeks and older
Cons
  • Flea-only: no ticks, heartworm or intestinal worms
  • Prescription required from a veterinarian
  • Weight bands are narrow, so dosing must match the pet exactly
  • Some pets vomit or drool after taking it
  • Only one store lists this pack new

Comfortis 270mg for Cats 6.1-12 lbs and Dogs 10-20 lbs, 6 Pack prices at every store

  • California Pet PharmacyNew

    In stock

    $124.69Observed at 3:44 PM
    Visit store

Comfortis 270mg for Cats 6.1-12 lbs and Dogs 10-20 lbs, 6 Pack price history

Lowest price we've seen: $124.69 on Nov 4 at California Pet Pharmacy. Tracked across 1 store since Nov 4.

What reviewers say

Owners of the 4.6-out-of-5 rated product report fast flea die-off, often within a day, and say the beef flavor makes dosing easy. Complaints center on vomiting in sensitive pets and the cost of keeping a monthly oral flea product going.

Pros
  • Fleas gone within about a day
  • Chewable accepted by most cats and dogs
  • No greasy topical residue
Cons
  • Vomiting or drooling in some pets
  • Needs a vet prescription
  • Price per month adds up

Specifications

Targeted Pests
Fleas
Active Ingredient
Spinosad
Administration Method
Oral
Life Stage Age
Puppies 14 weeks or older, Kittens 14 weeks or older
Treatment Frequency
Monthly
Animal Type
Dogs
Dosage Concentration
810 mg Spinosad
Dosage Duration
30 days
Formulation Type
Chewable tablet
Formulation
Beef-flavored
Lifecycle Targeted
Adults (kills fleas before they can lay eggs)
Treatment Type
Treatment, Prevention
Supply Duration
6 Month Supply
Supply Amount
6 tablets
Weight Range
40.1-60 lbs
Contains
Spinosad
Package Type
Box, Box (Blue Box)
Scent
Beef-flavored

Questions and answers

Is Comfortis worth it over a topical flea treatment?
It kills fleas faster than most topicals, within 30 minutes, and leaves no residue on fur or furniture. Topicals also cover ticks; Comfortis does not, so add a tick product if that matters.
How does Comfortis compare with NexGard or Bravecto?
Comfortis treats fleas only. NexGard and Bravecto also cover ticks, and Bravecto lasts 12 weeks per dose instead of one month. Choose Comfortis if fleas are the only concern and you want a fast oral kill.
What weight does the 270 mg tablet cover?
The 270 mg spinosad tablet is dosed for cats 6.1-12 lbs and dogs 10-20 lbs. Do not split or stretch it to other weights; use the tablet matched to your pet's weight.
How often do I give it, and how long does the box last?
Give one chewable tablet once a month with food. The 6-pack covers six months for one pet in this weight range.
What is in the box?
Six beef-flavored chewable tablets, each 270 mg spinosad, in a blue box. It is a prescription product, so you will need your vet to authorize the order.
When is the price lowest?
The best new price is $124.69 at California Pet Pharmacy as of November 4, 2026, about $20.78 per month. With only one store listing it new, watch for a second seller before expecting a discount.
Where is the Comfortis 270mg for Cats 6.1-12 lbs and Dogs 10-20 lbs, 6 Pack cheapest?
At California Pet Pharmacy, for $124.69, as of our latest check.
What do buyers say about the Comfortis 270mg for Cats 6.1-12 lbs and Dogs 10-20 lbs, 6 Pack?
Rated 4.6 out of 5 from 14 ratings.