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Deal.ai › iS Clinical › Serums & Face Oils

iS Clinical

iS Clinical Pro-Heal Serum Advance+

iS Clinical Pro-Heal Serum Advance+

4.9(2,100 ratings)

Best price now

$74.02at WalmartObserved at 4:03 AM

29% under what the other stores charge

Compared across 9 stores. Prices are checked against each store and labelled with when.

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Price facts

Lowest price today: $74.02 at Walmart (checked Nov 9, 2026).
Checked at 9 stores.

Our take on the iS Clinical Pro-Heal Serum Advance+

Pro-Heal Serum Advance+ is a daytime antioxidant serum built around vitamin C, vitamin E, olive leaf extract and a small amount of vitamin A. It is formulated for reactive and sensitive skin, and the brand positions it around calming redness and supporting skin healing. Reviewers with rosacea, eczema and post-acne marks tend to rate it highly for soothing irritated skin. The trade-offs are the small 15 mL bottle, the strong tingle some feel on first use, and the fact that it is a support serum rather than a standalone acne or wrinkle treatment.

Best forSensitive or reactive skin prone to rednessRosacea and eczema-prone facesPost-acne marks and uneven toneA morning antioxidant layer under sunscreen

Pros

Vitamin C, E and olive leaf extract give solid antioxidant protection
Vitamin A in a low-irritation form suits skin that cannot tolerate retinol
Reviewers report calmer redness and faster healing of blemishes
Light serum texture layers well under moisturizer and sunscreen
Paraben-free and marketed as hypoallergenic
Works for men and women and can be used under the eyes

Cons

Small 15 mL bottle runs out quickly with twice-daily use
Some users feel stinging or tingling, especially on broken skin
Not a substitute for a dedicated acne or prescription treatment
Vitamin A content is low, so fine-line results are gradual
Pipette bottle is glass and less travel-friendly

iS Clinical Pro-Heal Serum Advance+ prices at every store

WalmartNew
In stock
$74.02Observed at 4:03 AM
Visit Walmart
Lookfantastic USNew
In stock
$95.00Observed at 4:03 AM
Visit Lookfantastic US
DryEye RescueNew
In stock
$98.00Observed at 4:03 AM
Visit DryEye Rescue
eCosmeticsNew
In stock
$102.90Observed at 4:03 AM
Visit eCosmetics
BluemercuryNew
In stock
$104.00Observed at 4:03 AM
Visit Bluemercury
Dermstore.comNew
In stock
$104.00Observed at 4:03 AM
Visit Dermstore.com
LovelySkin.comNew
In stock
$104.00Observed at 4:03 AM
Visit LovelySkin.com
Art of Skin CareNew
In stock
$104.00Observed at 4:03 AM
Visit Art of Skin Care
Shop Rescue SpaNew
In stock
$104.00Observed at 4:03 AM
Visit Shop Rescue Spa

Also available at

Mayo Clinic StoreCheck price at Mayo Clinic Store
JomashopCheck price at Jomashop
iS ClinicalCheck price at iS Clinical
International OrangeCheck price at International Orange
Aida Bicaj SkincareCheck price at Aida Bicaj Skincare
eBayCheck price at eBay
BluemercuryCheck price at Bluemercury

Store links may earn us a commission.

iS Clinical Pro-Heal Serum Advance+ price history

Lowest price we've seen: $74.02 on Nov 9 at Walmart. Tracked across 15 stores since Nov 9.

What reviewers say

4.9 / 52,100 ratings

With 2,100 ratings averaging 4.9 out of 5, owners mostly praise how it calms redness and irritation on sensitive skin. Many describe it as a staple for rosacea and post-procedure recovery. Complaints center on the small bottle and stinging on reactive skin.

What people mention

Redness reliefPraisedOwners with rosacea and reactive skin say redness and flushing calm noticeably with regular morning use.
IrritationMixedSome users feel stinging or tingling, particularly on active breakouts or after exfoliation, while others find it gentle.
Bottle sizeCriticisedReviewers note the 15 mL bottle empties fast when used twice daily as directed.
HealingPraisedMany say blemishes and post-acne marks clear faster and skin looks less inflamed.
TexturePraisedUsers describe a light, fast-absorbing serum that sits well under moisturizer and makeup.
Fine linesMixedThe vitamin A content is low, so smoothing of fine lines is gradual and modest.

About the iS Clinical Pro-Heal Serum Advance+

Amplify the effect of your creams with a serum. The packaging has a volume of 1.014 fl oz.

Specifications

Body Part: Face
Form: Serum
Skin Type: Sensitive skin
Active Ingredients: Vitamin E, Olive Leaf Extract, Vitamin A
Key Ingredient: Vitamin E, Vitamin A
Skin Concerns: Fine lines and wrinkles
Acne Treatment Type: Cystic acne

Questions and answers

Is Pro-Heal Serum Advance+ good for rosacea and sensitive skin?: It is one of the brand's most recommended serums for reactive skin. Reviewers with rosacea and eczema report less redness, though a few still feel a tingle on broken skin.
Can I use it with retinol or other acids?: It already contains a small amount of vitamin A, so layering a strong retinol on top can irritate sensitive skin. Many users alternate rather than combine them in the same routine.
How does it compare with the original Pro-Heal Serum?: The Advance+ version adds vitamin C and olive leaf extract to the original formula, giving broader antioxidant coverage. Users who found the original too strong often describe this one as better tolerated.
When should I apply it?: It is designed for morning use on clean skin before moisturizer and sunscreen. It can also be patted under the eyes.
Will it clear acne or acne scars on its own?: It supports healing and calms inflammation, which helps post-acne marks fade. It is not a dedicated acne treatment, so persistent cystic acne needs a targeted product or a dermatologist.
Is it fragrance-free and paraben-free?: It is paraben-free and marketed as hypoallergenic. Check the full ingredient list if you are sensitive to specific preservatives or botanicals.
Where is the iS Clinical Pro-Heal Serum Advance+ cheapest?: At Walmart, for $74.02, 29% under what the other stores charge, as of our latest check.
What do buyers say about the iS Clinical Pro-Heal Serum Advance+?: Rated 4.9 out of 5 from 2,100 ratings.
Where can I buy the iS Clinical Pro-Heal Serum Advance+?: 15 stores we checked sell it, including Walmart, Lookfantastic US, DryEye Rescue, eCosmetics, Bluemercury.

Stores we've priced the iS Clinical Pro-Heal Serum Advance+ at

Bluemercury deals and prices
eCosmetics deals and prices
Walmart deals and prices

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SUPER SERUM

Scar Treatment Type

Acne scars

Stretch Mark Treatment Type

Fine stretch marks

Contains

Vitamin E, Olive Leaf Extract, Vitamin A

Free Of

Paraben-free

Subtype

Hydrating serum

Type

Serum

Face Treatment Type

Serum

For Babies

No

For Kids

No

For Men

Yes

Effect

Firmer skin

Size

15 mL

Night / Day Use

Day

Tattoo Care

No

Use Highlights

Under Eye

Content

Vitamins, Retinol, Vitamin E, Vitamin C, Antioxidants, Vitamin ASource

Packaging

PipetteSource