Shop
  • Deals
  • Black Friday
  • Buying guides
  • Brands
  • Stores
Travel
  • Flight deals
  • Hotel deals
Company
  • Research
  • Press
  • deal.ai apps
Black Friday 2026
  • Walmart
  • Best Buy
  • Target
  • TVs
  • Laptops
  • Headphones
  • Apple
  • Gaming
  • Vacuums
  • Kitchen
  • Toys
  • Smartwatches
  • Tablets
  • Furniture
  • Mattresses
© Deal.ai Inc.
TermsPrivacy
BrowseBrowse deal.ai
Deal.ai › MySmile › Irrigators
MySmile
MySmile LP221 Cordless UVC Sterilizable Water Flosser

MySmile LP221 Cordless UVC Sterilizable Water Flosser

4.6(1,300 ratings)

Best price now

$45.49at Macy'sObserved at 12:33 AM

30% under what the other stores charge

Compared across 3 stores. Prices are checked against each store and labelled with when.

Visit Macy's

Ask our agent about this product

It checks today's price at every store, compares the alternatives and answers in about a minute.

Enter to send, Shift+Enter for a new line

Our take on the MySmile LP221 Cordless UVC Sterilizable Water Flosser

The MySmile LP221 is a cordless water flosser with an 11-ounce reservoir, three pressure settings and a UVC lamp that sterilizes the water before it reaches your mouth. It ships with eight tips, including orthodontic, plaque-seeker, tongue-cleaner and pocket tips, and an OLED screen shows the mode and water temperature. It is IPX7 waterproof and runs on a rechargeable lithium-ion battery. At $45.49 at Macy's as of November 7, 2026, it sits at the low end of its recent range and is the best new price among the three stores that carry it.

Best forBraces and orthodontic wearersPeople with implants, crowns or bridgesSmall bathrooms and travelBuyers who want a sterilizing flosser under $50
Pros
  • UVC lamp sterilizes water, a feature rare at this price
  • Eight tips cover braces, implants, tongue and general cleaning
  • OLED display shows mode and water temperature
  • IPX7 waterproof, so it can be used in the shower
  • 11-ounce tank is large for a cordless unit
  • One-year parts and labor warranty
Cons
  • Only three pressure settings, fewer than many rivals
  • Bulkier than travel-size flossers at about 3.5 inches wide
  • Replacement tips add ongoing cost
  • UVC cycle adds cleaning steps to the routine

MySmile LP221 Cordless UVC Sterilizable Water Flosser prices at every store

  • Macy'sNew

    In stock

    $45.49Observed at 12:33 AM
    Visit Macy's
  • TargetNew

    In stock

    $64.99Observed at 12:33 AM
    Visit Target
  • Best BuyNew

    Availability unknown

    $64.99Observed at 12:33 AM
    Visit Best Buy

Also available at

  • eBayCheck price at eBay
  • WalmartCheck price at Walmart
  • WalmartCheck price at Walmart
  • Ulta BeautyCheck price at Ulta Beauty
  • NordstromCheck price at Nordstrom
  • GQ BoxCheck price at GQ Box
  • eBayCheck price at eBay
  • MySmile TeethCheck price at MySmile Teeth
  • lenonlures.comCheck price at lenonlures.com
  • Reliable Dental Supply & ServiceCheck price at Reliable Dental Supply & Service
  • Groupon.comCheck price at Groupon.com
  • Vakker DentalCheck price at Vakker Dental
  • Zulily.comCheck price at Zulily.com
  • Touch of ModernCheck price at Touch of Modern

Store links may earn us a commission.

MySmile LP221 Cordless UVC Sterilizable Water Flosser price history

Lowest price we've seen: $45.49 on Nov 7 at Macy's. Tracked across 15 stores since Nov 7.

What reviewers say

  • 4.6 / 51,300 ratings

Ratings are strong at 4.6 out of 5 from about 1,300 buyers. Owners tend to like the cleaning power and the tip variety, especially for braces. Complaints center on the pump's noise and on the tank needing a refill mid-session.

What people mention
  • Cleaning powerPraisedOwners say it blasts out food debris that brushing misses, including around braces.
  • Tip varietyPraisedBuyers like getting orthodontic, plaque-seeker and tongue tips in the box.
  • NoiseCriticisedSeveral owners call the pump loud enough to notice in a small bathroom.
  • Tank sizeMixedThe 11-ounce tank is big for cordless, but some users still refill it mid-session.
  • Pressure settingsMixedThree modes work for most, but sensitive gums may want a finer low setting.
  • UVC featureMixedBuyers value the sterilizing lamp but say it adds time and steps to each use.

About the MySmile LP221 Cordless UVC Sterilizable Water Flosser

MySmile LP221 OLED 335ml Water Flosser with Water Temperature Indicator, and UVC Cleaner Water Purifying Lamp, 5 Modes (Soft, Normal, Pulse, and 120s UVC Cleaner Water Purifying) 8 Jet Pick Tips IPX7 Waterproof, Long Time Working Time. EPA Establishment Number: 103136-CHN-1 Removes plaque,8pcs tips for Orthodontics, Periodontitis, Bad Breath, Dental Implant, Dental Plaque. OLED Display Customizable Pressures Packaging List: 1pc Main Unit 1pc Charge Cord 1pc Manual 1pc Storage travel bag 4pcs Standard Tips for general cleaning 1pc Tongue Cleaner, Remove dental plaque build up for a fresh breath 1pc Plaque Seek Tips, clean around implant, crown and bridges 1pc Orthodontic Tips, Remove food debris caught in braces 1pc Pocket tips, rinse and massage deep blow the gumline

Specifications

Number Of Pressure Settings
3
Number Of Tips Included
8
Reservoir Capacity
11 ounces
Product Width
3.5 inches
Product Length
3.2 inches
Power Source
Battery-powered
Battery Chemistry
Lithium-ion

Questions and answers

Is the MySmile LP221 worth it?
At $45.49 at Macy's as of November 7, 2026, it is one of the cheapest flossers with a UVC sterilizer and eight tips. If you want a sterilizing cordless flosser without paying premium prices, it is a reasonable buy.
How does it compare with the Waterpik cordless flossers?
Waterpik models usually offer more pressure settings and a wider accessory line. The LP221 counters with the UVC lamp, an OLED display and eight included tips at a lower price.
How long does the battery last?
MySmile rates it for long working time per charge, and most owners report several days of normal use between charges. Heavy daily use with the UVC cycle will drain it faster.
What comes in the box?
The main unit, a charging cord, a manual, a travel bag and eight tips: four standard, one tongue cleaner, one plaque seeker, one orthodontic and one pocket tip.
Are replacement tips available?
Yes. The jet tips are replaceable, and standard MySmile jet tips fit the LP221.
When is it cheapest?
The current $45.49 at Macy's is at the low end of its recent range across the three stores that carry it. Watch for holiday sales, when cordless flossers typically dip further.
Where is the MySmile LP221 Cordless UVC Sterilizable Water Flosser cheapest?
At Macy's, for $45.49, 30% under what the other stores charge, as of our latest check.
What do buyers say about the MySmile LP221 Cordless UVC Sterilizable Water Flosser?
Rated 4.6 out of 5 from 1,300 ratings.
Where can I buy the MySmile LP221 Cordless UVC Sterilizable Water Flosser?
15 stores we checked sell it, including Best Buy, Macy's, Target, eBay, Walmart.

Stores we've priced the MySmile LP221 Cordless UVC Sterilizable Water Flosser at

  • Best Buy deals and prices
  • Macy's deals and prices
  • MySmile Teeth deals and prices
  • nordstrom.com deals and prices
  • Target deals and prices
  • Ulta Beauty deals and prices
  • Walmart deals and prices
  • Zulily.com deals and prices

More from MySmile

  • M
    MySmile Electric Toothbrush for Adults
    MySmile Electric Toothbrush for Adults
  • M
    MySmile Rechargeable Sonic Electric Toothbrush for Adults with 6 Brush Heads
    MySmile Rechargeable Sonic Electric Toothbrush for Adults with 6 Brush Heads
  • M
    MySmile LP211 Portable Water Flosser Cordless for Teeth Braces
    MySmile LP211 Portable Water Flosser Cordless for Teeth Braces
  • M
    MySmile Portable Cordless 350ML Water Dental Flosser
    MySmile Portable Cordless 350ML Water Dental Flosser
  • M
    MySmile DY156 Sonic Electric Toothbrush for Adults
    MySmile DY156 Sonic Electric Toothbrush for Adults
  • M
    MySmile Sonic Toothbrush & Replacement Heads Bundle
    MySmile Sonic Toothbrush & Replacement Heads Bundle
  • M
    MySmile Everyday Smile Bundle Water Flosser and Teeth Whitening Kit
    MySmile Everyday Smile Bundle Water Flosser and Teeth Whitening Kit
All MySmile deals and products →
Warranty - Parts
1 year
Warranty - Labor
1 year
Rechargeable Battery
YesSource
Color
BlackSource
Alcohol-Free
Yes
Flavor
Mint
Variety
Black
size
LP221 with UV LightSource
actual_color
BlackSource
multipack_quantity
1Source
Replaceable Head
Yes (jet tips)
Product Type
Water flosser
Subtype
Cordless water flosser
Included Accessories
8 Jet Tips
Supported Accessories
Jet tips (replacement)
Mechanism Type
Water flosser
Quantity
1