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This is a leave-on spot treatment built on 10% sulfur, the strongest sulfur level sold over the counter, plus 4% niacinamide for post-acne marks. You dab a thin layer on a pimple with a cotton swab, let it dry, and wash it off in the morning. It suits people with occasional stubborn pimples who want a targeted product rather than an all-over treatment. Against benzoyl peroxide spot gels it is gentler on fabric and less likely to bleach towels, but it works more slowly and smells of sulfur. Against salicylic acid spot treatments it hits inflamed pimples harder but is not a good fit for whole-face use.
In stock
Rated 4.5 out of 5 from 501 ratings. Buyers mostly report pimples looking calmer and smaller by morning, and many like that it does not bleach bedding the way benzoyl peroxide does. Complaints center on the sulfur odor and on dryness or peeling when it is overused.
Neutrogena Stubborn Acne Spot Drying Lotion is a spot treatment for acne-prone skin. It contains 10% sulfur, the maximum level of sulfur available over the counter, to penetrate pores and help eliminate stubborn acne. It also contains 4% niacinamide, which helps target dark spots and post-acne marks.
The formula is clinically proven to give fast-acting results, and pimples look visibly clearer after one use. It is fragrance-free, paraben-free, phthalate-free, dye-free and oil-free.
Cleanse your face first. Use a clean cotton swab to apply a thin layer to the affected area. Do not rub it in, and let it dry thoroughly. It can be applied overnight and removed in the morning with warm water. Use it in the evening, and pair it with Stubborn Acne Blemish patches in the morning for all-day treatment.




