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Simparica is Zoetis's monthly oral flea and tick chewable for dogs, given as a flavored tablet dogs usually take like a treat. The purple box covers dogs from 5.6 to 11 lbs, and this listing is a 3-pack, so three months of protection. The best new price is $126.31 at Tractor Supply Co as of November 7, 2026, with only one store pricing it new, so there is little competition to push it lower.
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Lowest price we've seen: $126.31 on Nov 7 at Tractor Supply Co. Tracked across 1 store since Nov 7.
Owners of small dogs generally report Simparica works well, with fleas and ticks gone within a day and few side effects. A minority describe vomiting, lethargy or diarrhea after dosing, and some dogs balk at the taste.