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Neosporin + Lidocaine Antibiotic Ointment vs Neosporin + Pain Relief Ointment

Both are Neosporin triple-antibiotic ointments with a pain reliever, so the real choice is size and price. Product A adds lidocaine and comes in a 0.5 oz tube for $8.28 at Walmart as of November 7, 2026. Product B is a 1 oz tube (listed as a 3-piece multipack) for $9.99 at Amazon as of November 7, 2026, which is far more ointment per dollar. Buy B for a family first-aid kit and A for a small kit or handbag where fast numbing matters.

Today the Neosporin + Lidocaine Antibiotic Ointment costs $1.50 less at its best price.

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Neosporin
Neosporin + Lidocaine Pain Relieving Antibiotic

Neosporin + Lidocaine Antibiotic Ointment

Neosporin + Lidocaine Pain Relieving Antibiotic

4.8(684 ratings)
$8.49at AmazonObserved at 7:52 AM
See all prices and details
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Choose the Neosporin + Lidocaine if you want a small tube with fast numbing for painful cuts and burns and you value a compact size over cost per ounce.

Pros
  • Contains lidocaine for fast numbing of painful cuts and burns
  • Triple antibiotic formula protects against infection for 24 hours
  • Small 0.5 oz tube fits a purse or glove box
  • Lowest entry price of the two at $8.28
Cons
  • Only 0.5 oz, so it runs out fast with regular use
  • Costs about $16.56 per ounce, roughly double product B
  • Lidocaine can sting or irritate sensitive skin
  • Fewer ratings than product B
Neosporin
Neosporin + Pain Relief First Aid Ointment

Neosporin + Pain Relief Ointment

Neosporin + Pain Relief First Aid Ointment

$9.99at AmazonObserved at 7:51 AM
See all prices and details
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Choose the Neosporin + Pain Relief if you want the most ointment for the money and a larger tube for a household first-aid kit.

Pros
  • Twice the ointment for about $1.71 more
  • About $9.99 per ounce, much cheaper per use
  • Non-greasy, fragrance-free formula spreads smoothly
  • Large rating base: 4.8 out of 5 from 4,840 at Walmart
Cons
  • Larger tube is less pocketable
  • Some reviewers call it pricey
  • One reported delivery with missing items
  • Pain relief takes about 15 minutes, slower than lidocaine

What separates them

Neosporin + Lidocaine Antibiotic OintmentNeosporin + Pain Relief Ointment
Active ingredientsBacitracin zinc, neomycin sulfate, polymyxin B sulfate plus lidocaineBacitracin zinc, neomycin sulfate, polymyxin B sulfate plus pramoxine (pain reliever)
Size0.5 oz (14.2 g)1 oz (28.3 g), listed as a 3-piece multipack
Price$8.28 at Walmart as of November 7, 2026$9.99 at Amazon as of November 7, 2026
Price per ounceAbout $16.56 per ozAbout $9.99 per oz (or about $3.33 per piece if the 3 pieces are separate tubes)
Pain relief speedFast-acting lidocaine for maximum-strength numbingPain reliever with results in about 15 minutes
TextureOintmentOintment, described as non-greasy and fragrance free
Rating volume4.8 out of 5 from 684 ratings4.8 out of 5 from 4,840 ratings at Walmart and 1,711 at Google Shopping
Best forSmall kits, travel, single wounds needing numbingHousehold kits, repeated use, families

Price history

  • Neosporin + Lidocaine Antibiotic Ointment: lowest $8.49 on Nov 7 at Target.
  • Neosporin + Pain Relief Ointment: lowest $6.99 on Nov 7 at House Of Ambrose Wine & Spirits.

Prices at every store

Neosporin + Lidocaine Antibiotic Ointment

  • TargetNew

    In stock

    $8.49+ $5.99 shippingObserved at 9:00 AM
    Visit Target
  • WalgreensNew

    In stock

    $8.99+ $5.99 shippingObserved at 9:00 AM
    Visit Walgreens
  • Walgreens.comNew

    In stock

    $8.99+ $5.99 shippingObserved at 7:51 AM
    Visit Walgreens.com
  • AmazonNew

    Availability unknown

    As an Amazon Associate, Deal.ai earns from qualifying purchases.

    $8.49Observed at 7:52 AM
    Visit Amazon

Also available at

  • CVS PharmacyCheck price at CVS Pharmacy
  • WalmartCheck price at Walmart

Store links may earn us a commission. Some prices via Klarna.

All 7 stores and price history →

Neosporin + Pain Relief Ointment

  • TargetNew

    In stock

    $9.99+ $5.99 shippingObserved at 9:00 AM
    Visit Target
  • WalmartNew

    In stock

    $9.88+ $6.99 shippingObserved at 7:51 AM
    Visit Walmart
  • AmazonNew

    Availability unknown

    As an Amazon Associate, Deal.ai earns from qualifying purchases.

    $9.99Observed at 7:51 AM
    Visit Amazon
  • House Of Ambrose Wine & SpiritsNew

    Availability unknown

    $6.99+ $19.99 shippingObserved at 7:51 AM
    Visit House Of Ambrose Wine & Spirits

Store links may earn us a commission. Some prices via Klarna.

All 6 stores and price history →

Specs compared

SpecNeosporin + Lidocaine Antibiotic OintmentNeosporin + Pain Relief Ointment
TypePain & FeverAntibiotic, Antiseptic
multipack_quantity13
size0.5 oz1oz (28.3g)
BrandNeosporinNeosporin
Product lineDual ActionNeosporin
FormOintmentOintment
Required storage conditionAmbient StorageAmbient Storage
ManufacturerJohnson & JohnsonJohnson & Johnson
Product net content parent0.5 Ounces1 Ounces
Net content statement0.5oz/14.2g1oz (28.3g)
Product net content uomOunceOunce
Items included1 Tube of Antibiotic OintmentNeosporin + Pain Relief First Aid Ointment
Show all 38 specsShow fewer specs
SpecNeosporin + Lidocaine Antibiotic OintmentNeosporin + Pain Relief Ointment
Retail packagingSingle PieceSingle Piece
Active SubstanceNone—
Weight/pack. (oz)0.5—
Dosage FormOintment—
colorOther—
Over-the-counter medicine typePain Relief—
Health concernPain Relief—
Age groupAdult—
Symptomspain relief—
Active ingredient name

What reviewers say

Neosporin + Lidocaine Antibiotic Ointment

  • 4.8 / 5684 ratings

Users rate it highly for effectiveness and pain relief. Many mention it stings less than plain Neosporin and helps wounds heal quickly. Some report skin irritation or allergic reactions.

What people mention
  • Pain reliefPraisedUsers say the lidocaine numbs pain fast.
  • HealingPraisedMany report wounds heal quickly with no infection.
  • Allergic reactionCriticisedA few users developed a rash or itching after use.
  • StingingMixedSome feel a brief sting when applying, others don't.

Neosporin + Pain Relief Ointment

  • 4.8 / 5Walmart · 4,840 ratings
  • 4.8 / 5Google Shopping · 1,711 ratings

Reviewers rate it highly, praising how it soothes minor cuts, scrapes and burns and how the added pain relief calms stinging quickly.

What people mention
  • Pain reliefPraisedBuyers say it calms the sting of minor cuts and burns, not just protects them.
  • TexturePraisedReviewers find it easy to spread and not overly greasy.
Reviews
  • Highly recommend.

Questions and answers

Which is better for a painful cut right now?
Product A. Its lidocaine numbs quickly, while product B's pain reliever takes about 15 minutes.
Which lasts longer?
Product B. It has 1 oz versus 0.5 oz, so it lasts about twice as long at the same usage rate.
Is product B worth the extra $1.71?
Yes for regular use. You get double the ointment for about $1.71 more, roughly $9.99 per ounce versus $16.56.
Can I use either on a burn?
Both are labeled for minor cuts, scrapes and burns. Do not use them on deep or infected wounds; see a doctor.
Are they the same antibiotic?
Yes. Both use bacitracin zinc, neomycin sulfate and polymyxin B sulfate. They differ in the pain reliever and the size.
Which is better for a first-aid kit?
Product B for a household kit because of the larger size and lower cost per ounce. Product A suits a small travel kit.

More comparisons

  • Neosporin + Lidocaine Pain Relieving Antibiotic vs Neosporin Original Antibiotic Ointment, 0.5 oz
  • Neosporin Original Antibiotic Ointment, 0.5 oz vs Neosporin + Pain Relief First Aid Ointment
Bacitracin Zinc
—
Inactive ingredientsInactive Ingredients—
GenderUnisex—
Active Ingredientbacitracin zinc, neomycin sulfate, polymyxin B …—
Treatment TypeBurn care—
ConditionMinor burns—
Application MethodOintment—
Application Frequency1-3 times daily—
Ingredient ListPetrolatum, Zinc, bacitracin zinc, neomycin sul…—
Container TypeTube—
Ingredient properties—Non-Greasy
Skin care concern—Burn, Blisters
Skin care key benefits—Protecting
Scent—Fragrance Free
Care and maint—Change when expired or as needed
Piece count—3
Count—3
Healing
Praised
Owners say it stays on wounds and helps them heal.
  • PriceCriticisedA few shoppers feel it costs more than they expect.