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Bayer Advantage II Flea Control for Large Cats

Bayer Advantage II Flea Control for Large Cats

Best price now

$51.92at ChewyVerified

Compared across 5 stores. Prices are checked against each store and labelled with when. Store links may earn us a commission. Price via Klarna.

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Our take on the Bayer Advantage II Flea Control for Large Cats

Advantage II for large cats is a topical flea treatment from Bayer for cats over 9 lbs. It kills fleas at all life stages, including eggs and larvae, and stays effective for a month per tube. The 4-pack at $51.92 at Chewy as of November 7, 2026 works out to about $13 per monthly dose, a normal price for this size rather than a markdown.

Best forOwners of cats over 9 lbsMulti-cat households buying a 4-month supplyTreating a flea infestation indoorsRoutine monthly flea prevention
Pros
  • Kills adult fleas plus eggs and larvae, breaking the life cycle
  • One topical application lasts a full month
  • Four tubes cover four months for one cat
  • Waterproof after it dries, so bathing is fine
  • Widely stocked, so refills are easy to find
Cons
  • Prescription-free but not effective against ticks
  • Cats must weigh over 9 lbs; wrong size risks underdosing
  • Some cats dislike the application or the smell
  • Not for kittens under 8 weeks

Bayer Advantage II Flea Control for Large Cats prices at every store

  • ChewyNew

    In stock

    $51.92Free shippingVerified
    Visit Chewy
  • WalmartNew

    In stock

    $51.99Free shippingVerified
    Visit Walmart
  • PetsmartNew

    In stock

    $52.99+ $5.99 shippingVerified
    Visit Petsmart
  • Tractor Supply CoNew

    In stock

    $51.99+ $13.99 shippingVerified
    Visit Tractor Supply Co
  • Lowe'sNew

    In stock

    $68.17Free shippingVerified
    Visit Lowe's

Also available at

  • Ace HardwareCheck price at Ace Hardware
  • PetCareRxCheck price at PetCareRx

Store links may earn us a commission. Some prices via Klarna.

Bayer Advantage II Flea Control for Large Cats price history

Lowest price we've seen: $51.92 on Nov 7 at Chewy. Tracked across 7 stores since Nov 7.

What reviewers say

Owners generally report that Advantage II clears fleas within a day or two and keeps them away with monthly use. Complaints center on the greasy spot at application and on cats that resist being treated.

What people mention
  • EffectivenessPraisedOwners say fleas drop off quickly and stay gone with regular monthly use.
  • ApplicationMixedThe tube is easy to squeeze, but the liquid leaves a greasy spot on the coat.
  • Cat reactionCriticisedSome owners report their cats scratch at the spot or seem bothered for a day.
  • DurationMixedMost get a full month of protection, though a few see fleas again before the next dose.
  • Size matchingCriticisedBuyers warn that the large-cat version is wrong for cats under 9 lbs.

Specifications

Food Type
Treats, Wet Food, Supplements, Dry FoodSource
No. of Packs (pack)
4Source
Color
PurpleSource
Age Group
AdultSource

Questions and answers

Does Advantage II kill flea eggs and larvae?
Yes. It targets fleas at every life stage, so it interrupts the cycle rather than only killing adults.
How often do I apply it?
Once a month. Each tube treats one cat for about 30 days, so the 4-pack lasts four months for a single cat.
Is it safe for kittens?
No. This large-cat formula is for cats over 9 lbs and at least 8 weeks old. Use the kitten or small-cat version for lighter animals.
Does it protect against ticks?
No. Advantage II is a flea-only product. Cats that need tick coverage require a different treatment.
Can I bathe my cat after applying it?
Yes, once the application site is dry. It is waterproof after drying, but avoid bathing in the first day or two.
When is the price lowest?
Multi-packs like this 4-pack usually cost less per dose than single tubes. The $51.92 at Chewy as of November 7, 2026 is about $13 per month.
Where is the Bayer Advantage II Flea Control for Large Cats cheapest?
At Chewy, for $51.92, as of our latest check.
Where can I buy the Bayer Advantage II Flea Control for Large Cats?
7 stores we checked sell it, including Chewy, Walmart, Tractor Supply Co, Petsmart, Lowe's.

Stores we've priced the Bayer Advantage II Flea Control for Large Cats at

  • Ace Hardware deals and prices
  • Lowe's deals and prices
  • Walmart deals and prices

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