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Elanco
Elanco K9 Advantix II Flea, Tick & Mosquito Prevention 2-Monthly Treatments

Elanco K9 Advantix II Flea, Tick & Mosquito Prevention 2-Monthly Treatments

Best price now

$14.98at ChewyChecked 5 h ago

Compared across 2 stores. Prices are checked against each store and labelled with when. Store links may earn us a commission. Price via Klarna.

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Price facts

  • Lowest price today: $14.98 at Chewy (checked Nov 11, 2026).
  • Checked at 2 stores.

Our take on the Elanco K9 Advantix II Flea, Tick & Mosquito Prevention 2-Monthly Treatments

K9 Advantix II is a topical spot-on for dogs that kills fleas, ticks and mosquitoes, and also repels and kills biting flies, lice and sand flies. It is one of the few dog flea products that also targets mosquitoes, which makes it useful in heartworm-risk areas, though it does not prevent heartworm itself. It suits dog owners who want broad parasite coverage in a monthly tube rather than an oral chew. Unlike oral flea pills, it works on contact, so fleas do not need to bite to die, but it is toxic to cats and must never be applied to them.

Best forDog owners in mosquito-heavy or heartworm-risk regionsDogs that refuse oral flea chewsMulti-dog households needing contact-kill flea controlOwners wanting tick and biting fly coverage too
Pros
  • Kills fleas, ticks and mosquitoes, plus repels biting flies
  • Contact kill means fleas die without biting first
  • Easy monthly topical application between the shoulder blades
  • Water-resistant after drying and remains effective if the dog gets wet
  • Widely stocked and available in multiple dog-size tubes
Cons
  • Highly toxic to cats; keep treated dogs away from them until dry
  • Leaves a greasy spot and a noticeable odor for a day or two
  • Needs 24 to 48 hours to spread and fully protect the dog
  • Does not prevent heartworm, only kills mosquitoes that land
  • Some dogs show temporary skin irritation at the application site

Elanco K9 Advantix II Flea, Tick & Mosquito Prevention 2-Monthly Treatments prices at every store

  • ChewyNew

    In stock

    $14.98+ $4.95 shippingChecked 5 h ago
    Visit Chewy
  • PetsmartNew

    In stock

    $14.99+ $5.99 shippingChecked 5 h ago
    Visit Petsmart

Store links may earn us a commission. Some prices via Klarna.

Elanco K9 Advantix II Flea, Tick & Mosquito Prevention 2-Monthly Treatments price history

Lowest price we've seen: $14.98 on Nov 11 at Chewy. Tracked across 2 stores since Nov 11.

What reviewers say

Owners generally report strong flea and tick control, especially in yards with heavy flea pressure, and value the added mosquito protection. Complaints center on the greasy residue, the smell, and occasional skin reactions at the spot-on site.

What people mention
  • Flea controlPraisedOwners say it clears existing fleas quickly and keeps new ones off for the month.
  • Mosquito coveragePraisedBuyers in mosquito-heavy areas value that it repels and kills mosquitoes, unlike most flea-only topicals.
  • Residue and odorCriticisedMany mention a greasy patch and a chemical smell that lasts a day or two after application.
  • Skin reactionsMixedMost dogs show no issue, but some owners report redness or scratching at the application site.
  • Cat safetyCriticisedOwners with cats warn that it is toxic to them and requires keeping treated dogs separated until dry.
  • Tick performanceMixedTick control is generally good, though some owners still find attached ticks before they die.

Specifications

Food Type
SupplementsSource
Color
WhiteSource

Questions and answers

How is K9 Advantix II different from Frontline Plus?
Both are monthly topicals that kill fleas and ticks. K9 Advantix II adds mosquitoes, biting flies and lice, while Frontline Plus adds lice but not mosquitoes. K9 Advantix II is also toxic to cats; Frontline Plus is not.
Can I use it on a dog that lives with cats?
Only with strict separation. The product is highly toxic to cats, so keep cats away from the treated dog until the application site is completely dry, which usually takes a day or two.
How long does it take to work?
Fleas start dying within hours, but the product needs about 24 to 48 hours to spread over the skin and reach full protection. Bathing or swimming right after application reduces effectiveness.
Does it prevent heartworm?
No. It kills and repels mosquitoes, which can carry heartworm, but it is not a heartworm preventive. Dogs still need a separate heartworm medication prescribed by a vet.
Which tube size does my dog need?
Dosing is by weight, in four bands from very small dogs up to large dogs over 55 pounds. Use the band that matches your dog's current weight and do not split a large-dog tube among small dogs.
Is it safe for puppies?
It is labeled for puppies from 7 weeks of age and for pregnant or nursing dogs. Check with a vet first for very young, ill or medicated dogs.
Where is the Elanco K9 Advantix II Flea, Tick & Mosquito Prevention 2-Monthly Treatments cheapest?
At Chewy, for $14.98, as of our latest check.
Where can I buy the Elanco K9 Advantix II Flea, Tick & Mosquito Prevention 2-Monthly Treatments?
2 stores we checked sell it, including Chewy, Petsmart.

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