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Simparica Trio is a monthly oral chew that combines heartworm prevention, flea and tick control, and treatment of roundworms and hookworms in one dose. It starts killing fleas within 4 hours and reaches full flea kill by 8 hours, and it covers six tick species, more than other monthly oral chews. The liver-flavored chew is sized for dogs weighing 5.6–11 lbs and is given once a month. It suits owners who want to replace several separate parasite products with a single step, though it requires a vet's prescription and consistent monthly dosing.
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Lowest price we've seen: $39.47 on Nov 15 at Amazon. Tracked across 3 stores since Nov 15.
Owners rate Simparica Trio highly, praising the convenience of one monthly chew covering fleas, ticks and heartworm. Most report good flea and tick control and easy dosing. A few mention stomach upset or reluctance to eat the chew.
Simparica Trio is a monthly chewable for dogs that combines heartworm prevention, flea and tick control, and roundworm and hookworm treatment in one liver-flavored chew. This size is for extra small dogs weighing 5.6–11 lbs (2.6–5 kg). It is safe for dogs and puppies 8 weeks of age and older.
It contains three active ingredients. Sarolaner kills fleas and ticks. Moxidectin prevents heartworm larvae from developing into adult worms. Pyrantel pamoate paralyzes intestinal roundworms and hookworms so they can be expelled. In clinical studies, a single monthly dose gave 100% protection against heartworm disease.
Fleas start dying within 4 hours of dosing, with 100% eliminated by 8 hours. Killing fleas also prevents flea tapeworm infection. The chew kills six tick species and helps prevent infections that may cause Lyme disease by killing black-legged (deer) ticks. Give one chew a month, with or without food, and make sure the dog eats the whole chew.
