Is selegiline worth it for an older dog?

It is worth trying if your vet diagnoses cognitive dysfunction. It is not a cure, but many owners see modest improvement in alertness and sleep within 4 to 8 weeks. Stop and call your vet if behavior worsens.

How is it different from Anipryl?

Anipryl is the brand name; this is the generic with the same active ingredient, selegiline hydrochloride. The generic is usually much cheaper per tablet.

How do I give the tablet?

Give one 5 mg tablet once daily in the morning, mixed with food. Follow your vet's dose, which may differ for Cushing's disease.

What side effects should I watch for?

Watch for vomiting, loss of appetite, confusion or new aggression. Report any of these to your vet, who may lower the dose or stop the drug.

Can it be combined with other medications?

Not with other MAO inhibitors, and caution is needed with serotonin-boosting drugs and some pain medications. Tell your vet every drug and supplement your dog takes.

When is the price lowest?

Only one store, VetRxDirect a Pet Pharmacy, listed it at $1.54 per tablet as of November 4, 2026, so there is no cheaper listing to wait for. Ask your vet about a written prescription so you can compare pharmacies.

Where is the Selegiline 5mg Tablet cheapest?

At VetRxDirect a Pet Pharmacy, for $1.54, as of our latest check.

Selegiline 5mg Tablet

Best price now

$1.54at VetRxDirect a Pet PharmacyObserved at 3:07 PM

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Our take on the Selegiline 5mg Tablet

Selegiline hydrochloride 5 mg tablets are a prescription oral drug for dogs, given once daily mixed with food. In dogs it is used mainly for canine cognitive dysfunction (the dog version of age-related mental decline) and sometimes for Cushing's disease or behavioral problems. This is a generic version, so it costs far less than the brand-name Anipryl tablets. The best new price is $1.54 per tablet at VetRxDirect a Pet Pharmacy as of November 4, 2026, and only one store lists it, so there is no price competition to compare.