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Selegiline HCl 5 mg Dog Tablets for Cognitive Dysfunction and Cushing’s Disease

Selegiline HCl 5 mg Dog Tablets for Cognitive Dysfunction and Cushing’s Disease

Best price now

$45.90at HealthWarehouse.comObserved at 3:51 PM

Compared across 2 stores. Prices are checked against each store and labelled with when.

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Our take on the Selegiline HCl 5 mg Dog Tablets for Cognitive Dysfunction and Cushing’s Disease

Selegiline HCl 5 mg tablets are a prescription MAOI for dogs, sold as the generic equivalent of Anipryl. Vets prescribe it mainly for canine cognitive dysfunction ("dog dementia") in senior dogs and for pituitary-dependent Cushing's disease. Most dogs take it once daily, and improvement can take a month or more. The best new price is $59.49 at Amazon as of November 4, 2026, and only one store lists it new, so there is no cheaper new option to compare against.

Best forSenior dogs showing cognitive declineDogs diagnosed with pituitary-dependent Cushing's diseaseOwners seeking a lower-cost generic of AniprylOwners able to commit to daily dosing and vet monitoring
Pros
  • Generic Anipryl at a lower cost
  • Once-daily dosing for most dogs
  • Addresses both cognitive dysfunction and Cushing's disease
  • Well-established MAOI with decades of veterinary use
Cons
  • Prescription required; not available over the counter
  • Can take a month or more to show benefit
  • Interacts with other antidepressants, opioids and some foods
  • Only one store lists it new, so price competition is limited
  • Tablets are 5 mg, so larger dogs need multiple tablets per dose

Selegiline HCl 5 mg Dog Tablets for Cognitive Dysfunction and Cushing’s Disease prices at every store

  • HealthWarehouse.comNew

    In stock

    $45.90Free shippingObserved at 3:51 PM
    Visit store
  • AmazonNew

    Availability unknown

    As an Amazon Associate, Deal.ai earns from qualifying purchases.

    $59.49Observed at 3:06 PM
    Visit store

Also available at

  • Lambert Vet SuppliesCheck price at Lambert Vet Supplies
  • JeffersCheck price at Jeffers
  • Pet Supplies 4 LessCheck price at Pet Supplies 4 Less

Selegiline HCl 5 mg Dog Tablets for Cognitive Dysfunction and Cushing’s Disease price history

Lowest price we've seen: $45.90 on Nov 4 at HealthWarehouse.com. Tracked across 2 stores since Nov 4.

About the Selegiline HCl 5 mg Dog Tablets for Cognitive Dysfunction and Cushing’s Disease

Rx Selegiline HCl 5mg Tablets for Dogs

Selegiline is a prescription medication used to support brain health and quality of life in aging dogs. This monoamine oxidase inhibitor (MAOI) is commonly prescribed for dogs with Canine Cognitive Dysfunction (CCD), often referred to as “dog dementia,” helping improve awareness, activity level, and interaction. It is also used in the management of Cushing’s disease (pituitary-dependent hyperadrenocorticism). Selegiline HCl is the affordable generic equivalent of Anipryl, delivering the same trusted benefits at a lower cost.

Features:

• Supports cognitive function in senior dogs

• Commonly prescribed for Canine Cognitive Dysfunction (CCD)

• Used in the treatment of Cushing’s disease

• Generic alternative to Anipryl

• Once-daily dosing for most dogs

• Cost-effective prescription option

This medication should only be used under veterinary supervision. Selegiline may interact with certain medications, supplements, and foods, including other antidepressants and opioids. Do not administer without consulting your veterinarian, and report any changes in behavior, appetite, or health promptly.

Directions:

Please follow the directions and dosage prescribed by your veterinarian. The starting dose for canine cognitive dysfunction is 0.2 mg–0.45 mg per pound of body weight. It may take up to one month or longer to see improvement. The usual starting dose to treat Cushing’s disease is 0.45 mg per pound of body weight given once daily in the morning. If no result is seen within two months, the dose may be increased to 0.9 mg per pound of body weight. If there is still no response after one month at the increased dose, your pet should be reevaluated by your veterinarian.

Ingredients:

Selegiline hydrochloride, USP

This product requires a Valid prescription.

All prescription items are Non-Refundable and Non-Returnable .

Specifications

Active Ingredient
Selegiline HCl
Form
Tablet
Age Group
Dog
Dosage Form
Tablet
Application
Dog, Oral
Body Part
Dog
Ingredients
Selegiline HCl
Suitable For
Dog

Questions and answers

Is selegiline worth it for a senior dog with dementia?
Many vets consider it a reasonable first-line option for canine cognitive dysfunction, with reported gains in awareness, activity and interaction. It is not a cure, and some dogs show little change. Response usually takes a month or longer, so give it time before judging.
How does selegiline compare with Anipryl?
Selegiline HCl is the same active ingredient as Anipryl, and this product is marketed as its generic equivalent. The main difference is price, not effect. Confirm with your vet that the generic is acceptable for your dog.
What is the dose for cognitive dysfunction?
The listed starting dose is 0.2 to 0.45 mg per pound of body weight, once daily. A 20 lb dog falls around 4 to 9 mg, so a 5 mg tablet fits many small and mid-size dogs. Follow your vet's exact prescription.
Can it be used for Cushing's disease?
Yes, it is used for pituitary-dependent hyperadrenocorticism. It is not appropriate for every Cushing's case, and adrenal tumors are treated differently. Your vet should confirm the diagnosis before starting.
What drugs and foods should I avoid while my dog takes it?
Selegiline is an MAOI and can interact with other antidepressants, opioids and certain foods and supplements. Tell your vet about everything your dog takes. Report behavior, appetite or health changes promptly.
When is the price lowest?
Only one store lists it new, at $59.49 at Amazon as of November 4, 2026, so there is little price variation to shop. Check whether your vet's clinic or a compounding pharmacy beats that before ordering.
Where is the Selegiline HCl 5 mg Dog Tablets for Cognitive Dysfunction and Cushing’s Disease cheapest?
At HealthWarehouse.com, for $45.90, as of our latest check.
Where can I buy the Selegiline HCl 5 mg Dog Tablets for Cognitive Dysfunction and Cushing’s Disease?
5 stores we checked sell it, including HealthWarehouse.com, Amazon, Lambert Vet Supplies, Jeffers, Pet Supplies 4 Less.

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