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FRONTLINE Plus for Dogs is a monthly topical spot treatment for medium dogs weighing 23 to 44 lbs. It combines fipronil with (S)-methoprene, so it kills adult fleas and also stops flea eggs and larvae from developing, which breaks the flea life cycle. It also kills ticks that can carry Lyme disease and chewing lice, and it stays effective after the dog gets wet. It suits owners who want a long-established, waterproof product that covers the whole household's pets; rivals like NexGard and Bravecto are oral chews with longer dosing intervals, while FRONTLINE Plus is applied to the skin once a month.
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Owners rate it well overall and many have used it for years as a reliable monthly flea and tick routine. Complaints center on skin reactions at the spot, a greasy feel, and fleas that some owners say persist in heavy infestations.
FRONTLINE Plus for Dogs is a waterproof topical flea and tick treatment for medium-breed dogs weighing 23 to 44 lbs. It kills fleas, flea eggs, flea larvae, chewing lice and ticks, including ticks that can transmit Lyme disease. This pack contains 3 doses.
The formula uses fipronil and (S)-methoprene. It kills existing adult fleas, flea eggs and flea larvae, which breaks the flea life cycle and guards against further infestations.
Apply it to a single point on the dog. The treatment covers the entire body and collects in the sebaceous glands. These glands act as a reservoir that keeps replenishing the treatment on the coat, and it keeps working even if the dog gets wet. One dose each month protects against fleas and ticks for 30 days. It can be used on puppies at least eight weeks old that weigh 5 pounds or more.
