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Frontline Plus is a topical spot-on flea and tick treatment for small dogs weighing 5 to 22 lbs. Each applicator combines fipronil, which kills adult fleas and ticks, with (S)-methoprene, which stops flea eggs and larvae from developing. The formula is waterproof and lasts 30 days per dose, and it is approved for puppies 8 weeks and older. It is the vet-recommended standard against which chewable and prescription rivals are measured, though some owners report fleas returning in heavy-infestation homes.
Availability unknown
Lowest price we've seen: $37.12 on Nov 4 at Lion Country Supply. Tracked across 1 store since Nov 4.
Owners and vets widely trust Frontline Plus for routine flea and tick control on small dogs, and many report it clears infestations within a day. Some owners say fleas came back in heavy-infestation homes, and a few mention skin irritation or a lingering smell at the application site.
Frontline Plus is a flea and tick treatment for dogs and cats. It kills adult fleas and ticks, and it destroys flea eggs and larvae. It also stops all flea stages (eggs, larvae and pupae) from developing, which breaks the flea life cycle and helps prevent a future infestation.
The formula has two active ingredients. Fipronil kills adult fleas and ticks, and (S)-methoprene attacks flea eggs and larvae. The formula is stored in the oil glands of the pet's skin and protects for a full 30 days. At least 30 days are required between applications.
The formula is waterproof, so a pet can swim and be bathed without re-application. It is approved for use on puppies 8 weeks and older. Research shows it kills fleas for up to three months and ticks for at least one month. This small size is for pets 5 to 22 lbs.
