Frontline Plus
4.2Best price now
Compared across 2 stores. Prices are checked against each store and labelled with when.
Compared across 2 stores. Prices are checked against each store and labelled with when.
Frontline Plus is a monthly topical flea and tick treatment for dogs and cats, built on fipronil (9.8%) plus S-methoprene (8.8%). The second ingredient is the difference from plain Frontline: it kills flea eggs and larvae, not just adult fleas, which helps break the life cycle. It kills fleas, ticks and chewing lice for 30 days and stays waterproof 24 hours after application. The best new price is $41.16 at Walmart as of November 4, 2026, for the 3-treatment pack.
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In stock
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Lowest price we've seen: $40.98 on Nov 4 at Petco.com. Tracked across 7 stores since Nov 4.
Rated 4.2 out of 5 from about 13,800 ratings. Most owners say it clears fleas within a day or two and keeps them away with monthly use. Complaints center on the greasy residue, the smell, and fleas returning in areas with resistant populations.
Keep your dog protected with the #1 name in flea & tick protection*, FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years**— FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations and keep your pets protected year-round. References: *Data on file at Boehringer Ingelheim. **Data showing 20 years of trust in killing fleas and ticks is on file at Boehringer Ingelheim.



