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Simparica Trio Chewables for Medium Dogs vs Simparica TRIO Chewable

These are the same drug: sarolaner, moxidectin and pyrantel in the same pentagon chew, so protection is identical. Pick by pack size and weight band, not by brand. Owners report fast flea kill and good palatability with both. The 4.9 rating from 814 ratings is a larger sample than the 4.8 from 39, but the product is the same.

  • Choose the Simparica Trio medium-dog blue pack if your dog is 22.1–44 lbs and you want the 3-chew or 6-chew pack sized for that band.
  • Choose the Simparica TRIO chewable if you want the single-chew option or the 6-chew pack and your dog falls in the listed weight band.

Prices

  • Simparica Trio Chewables for Medium Dogs: $43.48 at Allivet Pet Pharmacy (last seen Nov 14)
  • Simparica TRIO Chewable: $234.77 at Allivet Pet Pharmacy (last seen Nov 14)
  • Difference: the Simparica Trio Chewables for Medium Dogs is $191.29 cheaper than the Simparica TRIO Chewable at the latest prices (Nov 14)
Simparica
Simparica Trio Chewables For Medium Dogs 22.1–44lbs (10.1-20Kg) Blue

Simparica Trio Chewables for Medium Dogs

Simparica Trio Chewables For Medium Dogs 22.1–44lbs (10.1-20Kg) Blue

4.8(39 ratings)
$43.48at Allivet Pet PharmacyChecked 11 h ago
See all prices and details
Visit Allivet Pet Pharmacy
Pros
  • Same three active ingredients as the other listing
  • Blue pack is clearly labeled for 22.1–44 lb dogs
  • Comes in 3 or 6 chews
  • No prescription needed at this store
Cons
  • Only one weight band on this page
  • Small rating sample
  • Fewer pack size choices
Simparica
Simparica TRIO Chewable

Simparica TRIO Chewable

4.9(814 ratings)
$234.77at Allivet Pet PharmacyChecked 11 h ago
See all prices and details
Visit Allivet Pet Pharmacy
Pros
  • Same formula, wider choice of weight bands
  • Single-chew option for trying it
  • Large rating sample
  • Liver-flavored chew most dogs take readily
Cons
  • Prescription required
  • Prescription items are non-returnable and non-refundable
  • No 3-chew pack

What separates them

Simparica Trio Chewables for Medium DogsSimparica TRIO Chewable
Active ingredientsSarolaner, moxidectin, pyrantelSarolaner, moxidectin, pyrantel
Weight bandMedium dogs, 22.1–44 lbs (10.1–20 kg)Selected weight band at checkout, puppy to XL
Pack sizes3 or 6 chews1 or 6 chews
PrescriptionSold without a vet prescriptionPrescription required
ReturnsStandard store return policyPrescription items non-returnable and non-refundable
Flea kill speedStarts within 4 hours, 100% by 8 hoursStarts within 4 hours, 100% by 8 hours
Flea efficacy duration35 days per dose35 days per dose
Rating sample4.8 from 39 ratings4.9 from 814 ratings

Price history

  • Simparica Trio Chewables for Medium Dogs: lowest $39.47 on Nov 15 at Amazon.
  • Simparica TRIO Chewable: lowest $39.47 on Nov 15 at Amazon.

Prices at every store

Simparica Trio Chewables for Medium Dogs

  • Allivet Pet PharmacyNew

    In stock

    $43.48Free shippingChecked 11 h ago
    Visit Allivet Pet Pharmacy
  • Smartway Pet SuppliesNew

    In stockReturn policy

    $80.00Checked 10 h ago
    Visit Smartway Pet Supplies

Also available at

  • AmazonCheck price at Amazon
  • Tractor Supply CompanyCheck price at Tractor Supply Company

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All 2 stores and price history →

Simparica TRIO Chewable

  • Allivet Pet PharmacyNew

    In stock

    $234.77Free shippingChecked 11 h ago
    Visit Allivet Pet Pharmacy
  • AmazonNew

    Availability unknown

    As an Amazon Associate, Deal.ai earns from qualifying purchases.

    $234.77Checked 11 h ago
    Visit Amazon

Also available at

  • 1800PetSupplies.comCheck price at 1800PetSupplies.com
  • KVSupplyCheck price at KVSupply
  • Tractor Supply CompanyCheck price at Tractor Supply Company

Store links may earn us a commission.

All 2 stores and price history →

Specs compared

SpecSimparica Trio Chewables for Medium DogsSimparica TRIO Chewable
Active ingredientssarolaner, moxidectin, and pyrantelsarolaner, moxidectin, and pyrantel
Route of administrationORALORAL
Tablet colorbrown (reddish brown)brown (reddish brown)
Tablet shapePENTAGON (5 sided) (rounded edges)PENTAGON (5 sided) (rounded edges)
Minimum age8 weeks of age8 weeks of age
Dosing frequencyone chew per monthone chew per month
Flea kill speedwithin 4 to 8 hours after treatmentwithin 4 to 8 hours after treatment
Flea efficacy duration35 days35 days
Paralysis tick kill98.9% of pre-existing paralysis ticks killed wi…98.9% of pre-existing paralysis ticks killed wi…
FlavorTasty liver flavoured chewTasty liver flavoured chew
AnimalDogDog
Puppy weight range1.25-2.5 kg—
Show all 15 specsShow fewer specs
SpecSimparica Trio Chewables for Medium DogsSimparica TRIO Chewable
XL weight range40.1-60 kg—
Weight range (Puppy)—1.25-2.5 kg
Weight range (XL)—40.1-60 kg

What reviewers say

Simparica Trio Chewables for Medium Dogs

  • 4.8 / 539 ratings

Owners rate it highly, with 4.8 out of 5 from 39 ratings. Buyers value getting the genuine Zoetis product sealed and in date, and many switched because it replaces several separate preventives with one monthly chew.

What people mention
  • CoveragePraisedOwners like that one chew covers heartworm, fleas, ticks and intestinal worms.
  • Flea and tick speedPraisedReviewers note fleas die within hours and paralysis ticks are killed quickly.
  • FlavorPraisedThe liver-flavored chew is taken readily by most dogs.
  • Monthly routineMixedOwners find monthly dosing simple but say a missed month leaves gaps.

Simparica TRIO Chewable

  • 4.9 / 5814 ratings

With 814 ratings averaging 4.9 out of 5, owners are strongly positive. They like the single monthly chew, the broad parasite cover and that dogs accept the liver flavor.

What people mention
  • FlavorPraisedOwners say most dogs eat the liver-flavored chew without a struggle.
  • ConveniencePraisedReviewers value replacing several parasite products with one monthly chew.
  • CoveragePraisedOwners like that fleas, ticks, heartworm and worms are handled together.
  • PrescriptionMixedBuyers note it can only be ordered with a vet's prescription.

Questions and answers

Are these two the same product?
Yes. Both are Simparica Trio with sarolaner, moxidectin and pyrantel in the same monthly chew. The difference is the pack, weight band and whether a prescription is required.
Which is better for a 30 lb dog?
Either works. The blue medium pack covers 22.1–44 lbs, and the other listing's medium band covers the same range. Match the chew to your dog's current weight.
Does one last longer?
No. Both give 35 days of flea efficacy per chew and are dosed once a month. Heartworm, tick and worm coverage follow the same monthly schedule.
Is it safe for puppies?
Both are labeled for puppies from 8 weeks old, with the smallest band starting at 2.8 lbs. Use the weight band that matches the puppy's weight at dosing.
Should I step up to the larger pack?
A 6-chew pack covers six months and avoids running out mid-month. A single chew suits a first try or a dog whose weight is changing.
Do I need a vet prescription?
One listing sells without a prescription; the other requires one and will not accept returns on prescription items. Check which you are ordering before you commit.

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More comparisons

  • Simparica Trio Chewable Tablet for Dogs 88.1-132.0 lbs Brown Box vs Simparica Trio Chewables For Medium Dogs 22.1–44lbs (10.1-20Kg) Blue
  • Simparica Trio Chewable Tablet for Dogs 88.1-132.0 lbs Brown Box vs Simparica TRIO Chewable