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Simparica TRIO is a once-monthly oral chew for dogs that combines flea, tick, heartworm and intestinal worm control in one tablet. Its three active ingredients — sarolaner, moxidectin and pyrantel — cover fleas, five tick types including paralysis ticks, heartworm, roundworms and hookworms, which rivals often split across two products. It starts killing fleas within 4 to 8 hours and keeps flea efficacy going for 35 days. Owners rate it highly for the liver-flavored chew dogs take readily and the convenience of one monthly dose; it needs a vet's prescription.
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Lowest price we've seen: $39.47 on Nov 15 at Amazon; $43.48 now. Tracked across 3 stores since Nov 15.
With 814 ratings averaging 4.9 out of 5, owners are strongly positive. They like the single monthly chew, the broad parasite cover and that dogs accept the liver flavor.
Simparica TRIO is a monthly chewable for dogs. It protects against heartworm disease, five types of ticks, fleas, roundworms and hookworms in one dose. The active ingredients are sarolaner, moxidectin and pyrantel.
It starts killing deer ticks within 8 hours and fleas within 4 hours. It is FDA-approved and has been demonstrated safe for puppies as young as 8 weeks old weighing at least 2.8 lbs. The chew is liver flavored and given once a month. It is dosed by the dog's weight and requires a vet's prescription.
