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Boehringer Ingelheim
Boehringer Ingelheim Frontline Plus Flea and Tick Treatment for Dogs

Boehringer Ingelheim Frontline Plus Flea and Tick Treatment for Dogs

Best price now

$19.43at Sierra Pet MedsObserved at 5:09 AM

41% under what the other stores charge

Compared across 3 stores. Prices are checked against each store and labelled with when.

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Our take on the Boehringer Ingelheim Frontline Plus Flea and Tick Treatment for Dogs

Frontline Plus is a monthly spot-on treatment for dogs that kills fleas, ticks and chewing lice. Each pipette combines fipronil with (S)-methoprene, an insect growth regulator that stops flea eggs and larvae from developing. It comes in four color-coded sizes by weight, from small dogs up to 10 kg to extra large dogs at 40–60 kg. The 3-pack best new price is $19.43 at Sierra Pet Meds as of November 4, 2026, with 3 stores selling it new.

Best forDog owners who want a monthly spot-on instead of an oral chewHouseholds fighting a flea infestation, since it also breaks the flea life cyclePuppies and dogs across all weight bracketsOwners who prefer a topical product over pills
Pros
  • Kills adult fleas, ticks and chewing lice
  • (S)-methoprene stops flea eggs and larvae from developing
  • Four weight-based sizes cover small to extra large dogs
  • Waterproof once dry, so swimming and bathing are fine after it sets
  • 3-pack covers three months for one dog
Cons
  • Monthly reapplication needed; it does not last a full season
  • Does not kill ticks as fast as some newer oral products
  • Leaves an oily spot at the application site until it dries
  • Fipronil resistance in some flea populations can reduce effectiveness
  • Dogs with sensitive skin may react at the application site

Boehringer Ingelheim Frontline Plus Flea and Tick Treatment for Dogs prices at every store

  • Sierra Pet MedsNew

    In stock

    $19.43Observed at 5:09 AM
    Visit store
  • fruugo.comNew

    In stock

    $32.95+ $5.99 shippingObserved at 5:09 AM
    Visit store
  • Chewy.comNew

    In stock

    $40.98+ $4.95 shippingObserved at 5:11 AM
    Visit store

Also available at

  • discountpetmedication.bizCheck price at discountpetmedication.biz
  • AmazonCheck price at Amazon
  • Petco.comCheck price at Petco.com
  • PetPawsRxCheck price at PetPawsRx
  • TargetCheck price at Target
  • Tractor Supply CompanyCheck price at Tractor Supply Company

Boehringer Ingelheim Frontline Plus Flea and Tick Treatment for Dogs price history

Lowest price we've seen: $19.43 on Nov 4 at Sierra Pet Meds. Tracked across 9 stores since Nov 4.

What reviewers say

Owners generally find Frontline Plus effective and easy to apply, and many have used it for years as a routine monthly treatment. Complaints center on fleas surviving in areas with resistant populations and on the greasy residue at the application spot.

Pros
  • Easy to apply between the shoulder blades
  • Works well for routine flea and tick control
  • Long track record and widely available
Cons
  • Fleas persist in some regions, likely due to resistance
  • Oily residue on the coat for a day or so
  • Some dogs show skin irritation at the spot

From Sierra Pet Meds

  • Spot-on treatment for advanced protection against fleas, ticks, and biting lice
  • Suitable for dogs of all sizes and puppies
  • Easy-to-use spot-on application
  • Apply monthly for consistent protection
Materials
Fipronil 100g/L, (S)-methoprene 90g/L
Care
Repeat the application monthly for consistent protection.
Packs
3, 6 and 12 dose packs available
In the box
3 pipettes (doses)

About the Boehringer Ingelheim Frontline Plus Flea and Tick Treatment for Dogs

Guard your loyal companion against unwelcome pests with Frontline Plus for dogs, a leading 'spot-on' remedy crafted for the advanced protection against fleas, ticks, and biting lice. Ideal for dogs of all sizes and puppies.

Benefits & Features:

Robust defence against fleas, ticks, and biting lice.

Easy-to-use 'spot-on' application.

Safe for puppies and dogs across various size brackets.

Directions for use:

Upright the Frontline Plus pipette and tap the narrow end so the fluid collects in the main body.

Break open the pipette tip.

Part the fur on your dog's back, preferably at the base of the neck before the shoulder blades.

Directly apply all contents of the pipette onto the skin in one spot.

For consistent protection, repeat the application monthly.

Ingredients: Fipronil 100g/L, (S)-methoprene 90g/L

Size variations:

Orange small dogs up to 10kg

Blue medium dogs between 10-20kg

Purple large dogs between 20-40kg

Red extra large dogs between 40-60kg

Protect your four-legged family member with the trusted strength of Frontline Plus. Purchase today and ensure a healthier, happier pet.

Specifications

Animal
Cat, Dog
Quantity
3 pack
Formulation
spot-on solutionSource
Fipronil concentration
98 mg/mL (=9.8%)Source
Methoprene concentration dogs
88 mg/mL for dogs and puppies (=8.8%)Source

Questions and answers

Is Frontline Plus worth it over a flea collar?
Yes for dogs with a real flea or tick problem. A collar gives slow, partial protection; Frontline Plus kills adult fleas and stops eggs and larvae from developing. It costs more per month but covers ticks and lice too.
How is it different from original Frontline?
Frontline Plus adds (S)-methoprene, an insect growth regulator that original Frontline lacks. That ingredient stops flea eggs and larvae from maturing, which helps break the infestation cycle in the home.
Which size pipette does my dog need?
Match the pipette color to weight: orange up to 10 kg, blue 10–20 kg, purple 20–40 kg, red 40–60 kg. Do not split a large pipette for a small dog; use the correct size.
Can I bathe my dog after applying it?
Once the solution has dried at the application site, usually within a few hours, bathing and swimming are fine. Avoid shampooing for about 48 hours after application so it absorbs into the skin.
What is in the box?
Three pipettes, one monthly dose each, in the size you order. The 3-pack covers three months for one dog.
When is the price lowest?
Multi-packs and the larger dog sizes usually give the lowest cost per dose. The 3-pack at $19.43 at Sierra Pet Meds as of November 4, 2026 is the best new price among 3 stores.
Where is the Boehringer Ingelheim Frontline Plus Flea and Tick Treatment for Dogs cheapest?
At Sierra Pet Meds, for $19.43, 41% under what the other stores charge, as of our latest check.
Where can I buy the Boehringer Ingelheim Frontline Plus Flea and Tick Treatment for Dogs?
9 stores we checked sell it, including Chewy.com, Sierra Pet Meds, fruugo.com, discountpetmedication.biz, Amazon.

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Methoprene concentration cats
118 mg/mL for cats and kittens (=11,8%)Source
Parasites controlled
Fleas, Ticks, Chewing liceSource
Dose small dogs
1 pipette with 0.67 mLSource
Dose medium dogs
1 pipette with 1.34 mLSource
Dose large dogs
1 pipette with 2.68 mLSource
Dose very large dogs
1 pipette with 4.02 mLSource
Dose cats
1 pipette with 0.5 mLSource
Acute oral LD50 rats
750 mg/kgSource
Acute dermal LD50 rats
>5000 mg/kgSource