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Elanco
Elanco Advantage II for Dogs

Elanco Advantage II for Dogs

Best price now

$50.97at Chewy.comChecked 5 h ago

Compared across 4 stores. Prices are checked against each store and labelled with when.

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Price facts

  • Lowest price today: $50.97 at Chewy.com (checked Nov 11, 2026).
  • Checked at 4 stores.

Our take on the Elanco Advantage II for Dogs

Advantage II is a monthly topical flea treatment for dogs from Elanco, the maker of the original Advantage line. It kills adult fleas, larvae and eggs, with the label claiming fleas die within 12 hours and protection lasts 30 days. It is waterproof after 24 hours and needs no prescription, which makes it simpler than vet-only oral chews. Unlike chewables such as Bravecto or NexGard, it has no tick coverage and no systemic action, so fleas must contact the treated skin. Long-term owners call it reliable and gentle on skin; some report fading results or resistance in heavy-infestation homes.

Best forOwners who prefer a topical over an oral chewDogs that vomit or refuse flea chewsMulti-dog homes wanting a no-prescription optionRoutine monthly flea prevention
Pros
  • Kills fleas, larvae and eggs, breaking the life cycle
  • Label claims fleas die within 12 hours
  • Waterproof after 24 hours
  • No prescription needed
  • Fragrance-free and easy to apply between the shoulder blades
Cons
  • No tick coverage
  • Fleas can persist for weeks if the home is not treated too
  • Some owners report reduced or no effectiveness
  • Needs monthly reapplication, unlike 3-month chewables
  • Dogs must weigh 11-20 lbs and be at least 7 weeks old for this size

Elanco Advantage II for Dogs prices at every store

  • WalmartNew

    In stock

    $50.97Free shippingChecked 5 h ago
    Visit Walmart
  • Chewy.comNew

    In stock

    $50.97Free shippingChecked 5 h ago
    Visit Chewy.com
  • PetsenseNew

    In stock

    $50.99Free shippingChecked 5 h ago
    Visit Petsense
  • PetSmartNew

    In stock

    $52.99+ $6.99 shippingChecked 5 h ago
    Visit PetSmart

Also available at

  • Ace HardwareCheck price at Ace Hardware
  • Allivet Pet PharmacyCheck price at Allivet Pet Pharmacy
  • AmazonCheck price at Amazon
  • Petco.comCheck price at Petco.com
  • Pets on BroadwayCheck price at Pets on Broadway
  • Pet SupermarketCheck price at Pet Supermarket
  • Revival Animal HealthCheck price at Revival Animal Health
  • Tractor Supply CompanyCheck price at Tractor Supply Company
  • Valley Vet SupplyCheck price at Valley Vet Supply

Elanco Advantage II for Dogs price history

Lowest price we've seen: $50.97 on Nov 11 at Walmart. Tracked across 13 stores since Nov 11.

What reviewers say

Long-term users tend to be loyal, saying fleas clear within days and problems stay away for years. A minority report brief or no results, and some worry about flea resistance.

What people mention
  • EffectivenessMixedMany say fleas die within days, but some report brief or no results.
  • Ease of usePraisedOwners find the topical simple to apply between the shoulder blades.
  • Skin irritationPraisedSeveral say it irritates skin less than other topical treatments.
  • ResistanceCriticisedSome long-term users suspect fleas have grown resistant to it.
  • Home treatmentCriticisedFleas persist for weeks when the house and yard are not also treated.

From Petco.com

  • Vet-recommended flea treatment and prevention for dogs weighing 11 to 20 lbs, at least 7 weeks of age
  • Kills adult fleas, flea larvae and flea eggs for total flea prevention and treatment
  • Same-day effectiveness: kills fleas within 12 hours of application and keeps working for 30 days
  • Easy-to-apply topical treatment, no prescription needed
  • Fragrance-free formula, waterproof after 24 hours
  • One single, monthly application
Sizes
4 ct
Sizing
For medium dogs weighing 11 to 20 lbs; not for dogs under 7 weeks of age.
Shipping
Ships Next Business Day; free shipping available.
In the box
4 applicator tubes of topical flea treatment

About the Elanco Advantage II for Dogs

Advantage II Medium Dog is a topical flea treatment and preventive for dogs and puppies. It kills adult fleas, flea larvae and flea eggs on contact, and it also controls lice. This helps break the flea life cycle and prevents further infestations.

It starts working the day it is applied, killing fleas within 12 hours, and keeps working for 30 days. The formula is fragrance-free and becomes waterproof 24 hours after application. It works on both indoor and outdoor dogs and doesn't require a prescription.

Apply it as one single application each month. It is made for dogs that weigh 11 to 20 lbs and are at least 7 weeks old.

Animal
Dog
Dog weight
11 to 20 lbs
Minimum age
7 weeks
Treats
Adult fleas, flea larvae, flea eggs and lice
Time to kill
Within 12 hours of application
Protection
30 days per application
Formula
Topical, fragrance-free
Waterproof
After 24 hours
Count
4 applicator tubes
Prescription
Not required

What buyers say

Buyers like
  • Rapidly eliminates fleas, often within days
  • Long-term users report zero flea problems for years
  • Easy to apply
  • Less skin irritation compared to other treatments
  • Strong brand loyalty among long-term users
  • Considered reliable and trusted flea prevention
Buyers complain about
  • Some report reduced effectiveness or only brief results
  • A few mention concerns about flea resistance
  • Some say it did not work at all
  • Fleas can persist for weeks if the home environment is not also treated

Specifications

Animal
Dog

Questions and answers

Does Advantage II kill ticks?
No. It targets fleas and lice only. If ticks are a concern, look at a product labeled for ticks, such as a chewable like NexGard or Bravecto.
How often do I apply it?
Once a month. Each tube protects for about 30 days, and the box holds 4 tubes, roughly a four-month supply for one dog.
Can I bathe my dog after applying it?
Yes, once 24 hours have passed. The formula is waterproof after that, so normal bathing and swimming are fine.
How is it different from a flea chew like NexGard?
Advantage II is a topical that works on contact and covers no ticks. Chewables are systemic, last longer per dose and usually include ticks, but need a prescription.
What age and weight can use this size?
This size is for dogs weighing 11 to 20 lbs and at least 7 weeks old. Smaller or larger dogs need the matching size.
Why are fleas still showing up after treatment?
The product kills fleas on the dog, not eggs and larvae in carpets and bedding. Treat the home and yard as well, and expect a few weeks before the infestation clears.
Where is the Elanco Advantage II for Dogs cheapest?
At Chewy.com, for $50.97, as of our latest check.
What do buyers say about the Elanco Advantage II for Dogs?
Buyers like: Rapidly eliminates fleas, often within days; Long-term users report zero flea problems for years; Easy to apply. Common complaints: Some report reduced effectiveness or only brief results; A few mention concerns about flea resistance.
Where can I buy the Elanco Advantage II for Dogs?
13 stores we checked sell it, including Walmart, Chewy.com, Petsense, PetSmart, Ace Hardware.

Stores we've priced the Elanco Advantage II for Dogs at

  • Ace Hardware deals and prices
  • Chewy.com deals and prices
  • Tractor Supply Company deals and prices
  • Walmart deals and prices

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