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Simparica TRIO Chewable Tablets for Dogs vs Bravecto Chews for Dogs

Simparica Trio is the better pick for puppies and for dogs that need heartworm and roundworm/hookworm coverage, since it is labeled from 8 weeks and combines three drugs in one monthly chew. Bravecto is the better pick for convenience and cost per month: one chew every 12 weeks, and at $65.83 at Bandana Rx as of November 4, 2026 versus $234.77 at Amazon as of November 4, 2026 for Simparica Trio, the price gap is large. Note that Bravecto does not cover heartworms or intestinal worms, and it is only labeled for dogs 6 months and older.

Today the Bravecto Chews for Dogs costs $168.94 less at its best price.

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Simparica
Simparica TRIO Chewable Tablets for Dogs

Simparica TRIO Chewable Tablets for Dogs

$234.77at AmazonObserved at 5:09 AM
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Choose the Simparica Trio if you have a puppy over 8 weeks, or you want flea, tick, heartworm and roundworm/hookworm protection from a single monthly chew.

Pros
  • Covers fleas, ticks, heartworm and two intestinal worms in one chew
  • Safe for puppies from 8 weeks
  • Kills fleas in 4 to 8 hours and paralysis ticks within 24 hours
  • Monthly dosing is easy to remember and pairs with a monthly routine
Cons
  • Highest upfront price of the two
  • Needs a dose every month
  • Requires a prescription and a heartworm test before starting
Bravecto
Bravecto Chews for Dogs

Bravecto Chews for Dogs

$65.83at Bandana RxObserved at 5:11 AM
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Choose the Bravecto if your dog is at least 6 months old, heartworm prevention is handled separately, and you want one dose every 12 weeks at a much lower price.

Pros
  • One dose lasts 12 weeks, so four doses a year
  • Far cheaper per month at the listed price
  • Kills fleas fast, within 2 hours of dosing
  • Five strengths cover a wide weight range
Cons
  • No heartworm or intestinal worm coverage
  • Not labeled for dogs under 6 months
  • Lone star tick protection lasts only 8 weeks
  • Needs a prescription

What separates them

Simparica TRIO Chewable Tablets for DogsBravecto Chews for Dogs
Dosing intervalOnce a monthOnce every 12 weeks
Minimum age8 weeks6 months
Parasites coveredFleas, ticks, heartworm, roundworms, hookwormsFleas and ticks only
Flea protection duration35 days12 weeks
Lone star tickCovered as part of tick control8 weeks only, not 12
Flea kill speedWithin 4 to 8 hoursStarts killing fleas within 2 hours, kills all within 12 hours
FormLiver-flavored chewable tabletChewable tablet, several strengths
Price$234.77 at Amazon as of November 4, 2026$65.83 at Bandana Rx as of November 4, 2026

Price history

  • Simparica TRIO Chewable Tablets for Dogs: lowest $44.63 on Nov 4 at Petco.com.
  • Bravecto Chews for Dogs: lowest $65.83 on Nov 4 at Bandana Rx.

Prices at every store

Simparica TRIO Chewable Tablets for Dogs

  • Petco.comNew

    In stock

    $44.63Free shippingObserved at 5:09 AM
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  • AmazonNew

    Availability unknown

    As an Amazon Associate, Deal.ai earns from qualifying purchases.

    $234.77Observed at 5:09 AM
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All 2 stores and price history →

Bravecto Chews for Dogs

  • Bandana RxNew

    In stock

    $65.83Free shippingObserved at 5:11 AM
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  • AmazonNew

    Availability unknown

    As an Amazon Associate, Deal.ai earns from qualifying purchases.

    $80.99Observed at 5:09 AM
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Also available at

  • Chewy.comCheck price at Chewy.com
  • FBNCheck price at FBN
  • ShotVetCheck price at ShotVet
All 2 stores and price history →

Specs compared

SpecSimparica TRIO Chewable Tablets for DogsBravecto Chews for Dogs
AnimalDogDog
Dosing frequencyonce a monthsingle dose every 12 weeks
Minimum age8 weeks of age and older—
Sarolaner dosage0.54 mg/lb (1.2 mg/kg)—
Moxidectin dosage0.011 mg/lb (24 μg/kg)—
Pyrantel dosage2.27 mg/lb (5 mg/kg)—
Administration routeFOR ORAL USE IN DOGS ONLY—
Formflavored, chewable tablet—
Flea kill speedwithin 4 to 8 hours after treatment—
Flea efficacy duration35 days—
Paralysis tick killwithin 24 hours of treatment—
Flavorliver flavoured chew—
Show all 21 specsShow fewer specs
SpecSimparica TRIO Chewable Tablets for DogsBravecto Chews for Dogs
Active ingredient—fluralaner
Minimum dose—11.4 mg/lb (25 mg/kg) body weight
Flea protection duration—12 weeks
Tick protection duration—12 weeks
Lone star tick duration—8 weeks
Minimum dog age—6 months of age and older
Fluralaner content—1400
Available strengths—5 strengths
Package size—10 x 1 x 112.5mg

What reviewers say

Simparica TRIO Chewable Tablets for Dogs

Owners and vets generally rate Simparica Trio highly for convenience and fast flea control, and many report their dogs take the chew without fuss. The main complaints are cost and occasional stomach upset or refusal of the chew in picky dogs.

Pros
  • One chew replaces several separate products
  • Fast flea and tick knockdown
  • Most dogs accept the liver flavor
  • Simple monthly schedule
Cons
  • Higher cost than buying single-purpose products
  • Some dogs vomit or have loose stool after dosing
  • Picky dogs may spit out the chew
  • No tapeworm coverage

Bravecto Chews for Dogs

Owners generally rate Bravecto highly for convenience and flea control, and many report a full season with no fleas. The most common complaints are dogs refusing the chew and occasional vomiting or loose stool after dosing.

Pros
  • Lasts three months, so owners stop forgetting monthly doses
  • Clears existing flea infestations quickly
  • Chew form is easier than topicals for dogs that hate drops
Cons
  • Some dogs spit out or refuse the chew
  • Occasional vomiting or diarrhea after a dose
  • Price per chew is high even though it lasts longer

Questions and answers

Which is better for a puppy?
Simparica Trio. It is labeled for dogs 8 weeks and older, while Bravecto is only for dogs 6 months and older. Simparica Trio also adds heartworm and intestinal worm coverage a puppy needs.
Is Bravecto worth it if I still need heartworm prevention?
Only if you add a separate heartworm preventive. Bravecto covers fleas and ticks but not heartworms, so the total cost is Bravecto plus that product. Compare that combined cost against Simparica Trio's $234.77 at Amazon as of November 4, 2026.
Which lasts longer between doses?
Bravecto. One chew protects for 12 weeks against fleas and most ticks, though lone star ticks for 8 weeks. Simparica Trio is dosed monthly and its flea efficacy is stated at 35 days.
Which kills fleas faster?
Bravecto starts killing fleas within 2 hours and completes the kill within 12 hours. Simparica Trio kills fleas within 4 to 8 hours. Both are fast; Bravecto has the edge on onset.
Can I switch my dog from one to the other?
Yes, with your vet's guidance. Watch the dosing interval: a dog on monthly Simparica Trio moving to Bravecto gets one chew every 12 weeks, and heartworm prevention must be added separately. A dog moving to Simparica Trio needs a negative heartworm test first.
Which is cheaper per year?
Bravecto, at the listed prices. At $65.83 at Bandana Rx as of November 4, 2026, four doses a year cost about $263. Simparica Trio at $234.77 at Amazon as of November 4, 2026 is a monthly product, so twelve doses cost far more.

More comparisons

  • Bravecto Chews for Dogs vs NexGard PLUS
  • Bravecto for Dogs - 12-week dose (Rx) vs Bravecto Chews for Dogs
  • Simparica TRIO Chewable Tablets for Dogs vs NexGard PLUS
  • Bravecto for Dogs - 12-week dose (Rx) vs Simparica TRIO Chewable Tablets for Dogs

Buying guides that pick them

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