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Simparica Chewables for Dogs vs Simparica Trio Chewable Tablets for Dogs

Simparica Chewables is a single-ingredient flea and tick chew; Simparica Trio adds heartworm, roundworm and hookworm coverage in the same monthly dose. Trio is the better all-in-one for most owners, and it can start at 8 weeks versus 6 months for plain Simparica. Plain Simparica gives a higher sarolaner dose per pound and is the pick if your dog already gets a separate heartworm preventive. Both are liver-flavored chews owners report dogs take readily, and both carry a prescription requirement.

  • Choose the Simparica Chewables if your dog already takes a separate heartworm preventive and you only need flea and tick control.
  • Choose the Simparica Trio if you want one monthly chew to cover fleas, ticks, heartworm, roundworms and hookworms, or you have a puppy at least 8 weeks old.

Prices

  • Simparica Chewables for Dogs: $69.37 at Chewy.com (last seen Nov 9)
  • Simparica Trio Chewable Tablets for Dogs: $78.00 at Smartway Pet Supplies (checked today)
  • Difference: the Simparica Chewables for Dogs is $8.63 cheaper than the Simparica Trio Chewable Tablets for Dogs at the latest prices (Nov 9 and Nov 11)
Simparica
Simparica Chewables for Dogs

Simparica Chewables for Dogs

5(3 ratings)
$69.37at Chewy.comChecked Nov 9
See all prices and details
Visit Chewy.com
Pros
  • Simple single-ingredient flea and tick chew
  • Higher sarolaner dose per pound of body weight
  • Kills fleas fast and controls ticks for a month
  • Liver-flavored chew most dogs take without fuss
  • Six tablet strengths cover a wide weight range
Cons
  • No heartworm, roundworm or hookworm coverage
  • Not for puppies under 6 months
  • Needs a vet prescription
  • You still need a separate heartworm preventive
Simparica
Simparica TRIO Chewable Tablets for Dogs

Simparica Trio Chewable Tablets for Dogs

Simparica TRIO Chewable Tablets for Dogs

4.8(4 ratings)
$78.00at Smartway Pet SuppliesChecked 1 h ago
See all prices and details
Visit Smartway Pet Supplies
Pros
  • One monthly chew covers five parasite groups
  • Starts at 8 weeks, so puppies qualify
  • Kills six tick species and helps prevent Lyme
  • Flea protection holds up to 35 days
  • Fewer products and fewer dosing dates to track
Cons
  • Lower sarolaner dose per pound than plain Simparica
  • Contains moxidectin, so it is not for every dog; check with your vet
  • Needs a vet prescription
  • Some dogs may still refuse the chew despite the liver flavor

What separates them

Simparica Chewables for DogsSimparica Trio Chewable Tablets for Dogs
Parasite coverageFleas and ticks onlyFleas, ticks, heartworm, roundworms, hookworms
Active ingredientsSarolaner aloneSarolaner, moxidectin and pyrantel
Minimum ageOver 6 months8 weeks and older
Sarolaner dose per pound0.91 mg/lb0.54 mg/lb
Flea kill speedWithin 8 hours of attachmentWithin 4 to 8 hours after dosing
Flea protection durationOne monthUp to 35 days
Tick coverageTick control for one monthSix tick species, including deer ticks tied to Lyme
PrescriptionRequiredRequired

Price history

$44.63$20.99
Nov 4Nov 11
  • Simparica Chewables for Dogs: lowest $20.99 on Nov 11 at Bandana Rx.
  • Simparica Trio Chewable Tablets for Dogs: lowest $39.00 on Nov 11 at ShotVet.

Prices at every store

Simparica Chewables for Dogs

  • Chewy.comNew

    Availability unknown

    $69.37Checked Nov 9
    Visit Chewy.com
  • Heartland Veterinary Supply and PharmacyNew

    Availability unknown

    $79.24Checked Nov 9
    Visit Heartland Veterinary Supply and Pharmacy
  • VetRxDirect a Pet PharmacyNew

    Availability unknown

    $128.55Checked Nov 9
    Visit VetRxDirect a Pet Pharmacy
  • Koala HealthNew

    Availability unknown

    $128.55Checked Nov 9
    Visit Koala Health

Also available at

  • Allivet Pet PharmacyCheck price at Allivet Pet Pharmacy
  • AmazonCheck price at Amazon
  • Bandana RxCheck price at Bandana Rx
All 7 stores and price history →

Simparica Trio Chewable Tablets for Dogs

  • Smartway Pet SuppliesNew

    In stockReturn policy

    $78.00Checked 1 h ago
    Visit Smartway Pet Supplies

Also available at

  • Allivet Pet PharmacyCheck price at Allivet Pet Pharmacy
  • AmazonCheck price at Amazon
  • California Pet PharmacyCheck price at California Pet Pharmacy
Prices and history →

Specs compared

SpecSimparica Chewables for DogsSimparica Trio Chewable Tablets for Dogs
AnimalDogDog
Dosing frequencyonce a monthonce a month
Minimum ageover 6 months of age8 weeks of age and older
Formflavored, chewable tabletflavored, chewable tablet
Food TypeDog ChewDog Chew
Active ingredientsarolaner—
Minimum dosage0.91 mg/lb (2 mg/kg)—
Tablet strengths5, 10, 20, 40, 80, 120—
RouteFOR ORAL USE IN DOGS ONLY—
Flea protection durationone month—
Tick protection durationone month—
Tablet shapesquare shaped chewable tablets with rounded edg…—
Show all 25 specsShow fewer specs
SpecSimparica Chewables for DogsSimparica Trio Chewable Tablets for Dogs
Onset for fleaswithin 8 hours of attachment—
ColorGreen—
No. of Packs (pack)6—
Sarolaner dosage—0.54 mg/lb (1.2 mg/kg)
Moxidectin dosage—0.011 mg/lb (24 μg/kg)
Pyrantel dosage—2.27 mg/lb (5 mg/kg)
Administration route—FOR ORAL USE IN DOGS ONLY
Flea kill speed—within 4 to 8 hours after treatment
Flea efficacy duration—35 days

What reviewers say

Simparica Chewables for Dogs

Owners generally report Simparica works well, with fleas and ticks clearing quickly and few side effects. A minority describe vomiting, lethargy or loose stools after the chew, and some dogs refuse the flavor.

What people mention
  • EfficacyPraisedOwners say fleas and ticks are gone within a day or two of the first dose.
  • TasteMixedMany dogs eat it as a treat, but some owners say their dog refuses the flavor.
  • Stomach upsetCriticisedA minority report vomiting or loose stool after dosing, usually short-lived.
  • ConveniencePraisedOwners like skipping topical application and not worrying about baths or swimming.

Simparica Trio Chewable Tablets for Dogs

Owners generally report that Simparica Trio is easy to give and effective against fleas and ticks, and many like replacing several products with one chew. The most common complaints are vomiting, drooling or loose stools after a dose, and some owners say their dog refuses the chew.

What people mention
  • Flea and tick controlPraisedOwners report fleas and ticks gone within a day and no reinfestation while dosing stays on schedule.
  • Stomach upsetCriticisedA share of owners report vomiting, drooling or loose stools, usually after the first dose.
  • PalatabilityMixedMany dogs eat the liver chew as a treat, but some owners say their dog refuses it or spits it out.
  • ConveniencePraisedOwners value replacing separate flea, tick and heartworm products with one monthly chew.

Questions and answers

Which is better for a dog that already takes a heartworm preventive?
Plain Simparica Chewables. Adding Trio would duplicate heartworm prevention, so the simpler flea and tick chew is the cleaner fit.
Which is better for a puppy?
Simparica Trio. It is labeled for dogs 8 weeks and older, while plain Simparica requires the dog to be over 6 months.
Does Trio replace plain Simparica, or do I give both?
Give one or the other, never both in the same month. Trio already contains sarolaner, the active ingredient in plain Simparica.
Which lasts longer between doses?
Trio's flea efficacy is labeled up to 35 days; plain Simparica is labeled for one month. Both are dosed monthly, so the practical difference is small.
Is Trio worth stepping up to?
For most owners, yes. It folds heartworm and intestinal worm control into the same chew, which removes two or three separate products from the monthly routine.
Which kills fleas faster?
They are close. Plain Simparica starts killing fleas within 8 hours of attachment; Trio reaches full flea kill by 8 hours after dosing.

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Buying guides that pick them

  • Best flea treatments for dogs
Paralysis tick kill
—
within 24 hours of treatment
Flavor—liver flavoured chew
Age Group—Adult, Puppy
Special Diets—Fur & Skin Care