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Simparica Trio Chewable Tablets vs Simparica Trio Chewable Tablet for Dogs

These are the same drug, sarolaner, moxidectin and pyrantel, in the same liver-flavored monthly chew. The only real difference is the weight band: A is dosed for dogs 2.8 to 5.5 lb, B for dogs 11.1 to 22 lb. Buy the one that matches your dog's current weight. Both carry the same FDA approval for six tick types, heartworm, fleas, flea tapeworms, roundworms and hookworms, and owners consistently report dogs eat them readily.

  • Choose the Simparica Trio 2.8-5.5 lb if your dog weighs between 2.8 and 5.5 pounds, such as a toy breed puppy or small adult dog.
  • Choose the Zoetis Simparica Trio 11.1-22 lb if your dog weighs between 11.1 and 22 pounds, a small-to-medium adult or a puppy past eight weeks.

Prices

  • Simparica Trio Chewable Tablets: $203.51 at Chewy (checked today)
  • Simparica Trio Chewable Tablet for Dogs: $40.05 at Amazon (last seen Nov 14)
  • Difference: the Simparica Trio Chewable Tablet for Dogs is $163.46 cheaper than the Simparica Trio Chewable Tablets at the latest prices (Nov 14 and Nov 15)
Simparica Trio
Simparica Trio Dog Chewable Tablets 2.8-5.5 lb 6 Treatments

Simparica Trio Chewable Tablets

Simparica Trio Dog Chewable Tablets 2.8-5.5 lb 6 Treatments

4.6(628 ratings)
$203.51at ChewyChecked 9 h ago
See all prices and details
Visit Chewy

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Pros
  • Correct dose for very small dogs, including toy breeds
  • Same broad coverage as the larger size
  • Chew is small enough for tiny mouths
  • Six months of protection in one pack
Cons
  • Wrong dose for any dog over 5.5 lb
  • Needs a vet prescription
  • Not for puppies under eight weeks
Zoetis
Zoetis Simparica Trio Chewable Tablet 11.1-22 lbs 6 pcs

Simparica Trio Chewable Tablet for Dogs

Zoetis Simparica Trio Chewable Tablet 11.1-22 lbs 6 pcs

5(4 ratings)
$40.05at AmazonChecked 13 h ago
See all prices and details
Visit Amazon

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Pros
  • Correct dose for small-to-medium dogs
  • Covers heartworm, fleas, ticks and intestinal worms in one chew
  • Owners report dogs eat it without fuss
  • Six-month supply
Cons
  • Wrong dose for dogs under 11.1 lb or over 22 lb
  • Needs a vet prescription
  • Non-returnable once dispensed

What separates them

Simparica Trio Chewable TabletsSimparica Trio Chewable Tablet for Dogs
Weight bandDosed for dogs 2.8 to 5.5 lbDosed for dogs 11.1 to 22 lb
Active ingredientsSarolaner, moxidectin, pyrantelSarolaner, moxidectin, pyrantel
Parasite coverageHeartworm, fleas, six tick types, flea tapeworms, roundworms, hookwormsHeartworm, fleas, six tick types, flea tapeworms, roundworms, hookworms
Minimum ageEight weeks, at or above the labeled minimum weightEight weeks, at or above the labeled minimum weight
Dosing scheduleOne chew monthly, six per packOne chew monthly, six per pack
Flavor and acceptanceLiver-flavored chew, 9 of 10 dogs ate it in a studyLiver-flavored chew, 9 of 10 dogs ate it in a study
PrescriptionVet prescription requiredVet prescription required, and the item is non-returnable

Price history

  • Simparica Trio Chewable Tablets: lowest $203.51 on Nov 15 at Tractor Supply Co.
  • Simparica Trio Chewable Tablet for Dogs: lowest $40.05 on Nov 15 at Amazon.

Prices at every store

Simparica Trio Chewable Tablets

  • Tractor Supply CoNew

    In stock

    $203.51Free shippingChecked 9 h ago
    Visit Tractor Supply Co
  • ChewyNew

    In stock

    $203.51Free shippingChecked 9 h ago
    Visit Chewy
  • Valley Vet SupplyNew

    In stock

    $203.51Checked 9 h ago
    Visit Valley Vet Supply
  • AmazonNew

    Availability unknown

    As an Amazon Associate, Deal.ai earns from qualifying purchases.

    $203.51Checked 12 h ago
    Visit Amazon

Store links may earn us a commission. Some prices via Klarna.

All 6 stores and price history →

Simparica Trio Chewable Tablet for Dogs

  • Tractor Supply CoNew

    In stock

    $210.09Free shippingChecked 9 h ago
    Visit Tractor Supply Co
  • ChewyNew

    In stock

    $210.09Free shippingChecked 9 h ago
    Visit Chewy
  • BaxterBooNew

    In stock

    $210.09Checked 9 h ago
    Visit BaxterBoo
  • AmazonNew

    Availability unknown

    As an Amazon Associate, Deal.ai earns from qualifying purchases.

    $40.05Checked 13 h ago
    Visit Amazon

Store links may earn us a commission. Some prices via Klarna.

All 6 stores and price history →

Specs compared

SpecSimparica Trio Chewable TabletsSimparica Trio Chewable Tablet for Dogs
Food TypeSupplementsDog Chew
No. of Packs (pack)66
Age GroupAdultAdult, Puppy
Special DietsDigestion and StomachFur & Skin Care
Dog SizeMedium (11-25kg)—
Weight/pack. (oz)2.8—
ColorYellow, Gold—
SupplementsJoint & Bone—
AnimalDog—
Ingredients—Liver, Beef

What reviewers say

Simparica Trio Chewable Tablets

  • 4.6 / 5628 ratings

Rated 4.6 out of 5 across 628 ratings, owners largely report it is easy to give and effective at keeping fleas and ticks off. Complaints center on stomach upset in some dogs and the need for a vet visit and prescription.

What people mention
  • Ease of dosingPraisedOwners say most dogs eat the liver-flavored chew without a fight.
  • Flea and tick controlPraisedReviewers report fleas and ticks gone after starting the monthly chew.
  • Stomach upsetCriticisedSome owners report vomiting or loose stool, usually after the first dose.
  • Prescription requirementMixedBuyers note the vet visit and heartworm test add steps before the first dose.

Simparica Trio Chewable Tablet for Dogs

Owners and veterinarians generally rate Simparica Trio as a reliable, easy monthly all-in-one. The most common complaints are stomach upset in sensitive dogs and occasional refusal of the chew.

What people mention
  • ConveniencePraisedOwners like replacing separate flea, tick and heartworm products with a single monthly chew.
  • Stomach upsetCriticisedSome owners report vomiting or loose stools, especially in dogs with sensitive digestion.
  • PalatabilityMixedMost dogs take the liver and beef chew readily, but some refuse it or spit it out.
  • Flea controlPraisedUsers report fleas dying quickly and staying away with monthly dosing.

Questions and answers

Are these two products actually different?
No. Both are Simparica Trio, the same three active ingredients in the same monthly chew. Only the weight band on the label differs, so pick the one that fits your dog's weight.
Which one should I give a puppy?
Either, as long as the puppy is at least eight weeks old and its weight falls inside that product's band. A puppy under 5.5 lb takes A; one between 11.1 and 22 lb takes B.
What if my dog is between 5.5 and 11.1 lb?
Neither of these two sizes fits. Simparica Trio comes in other weight bands, so ask your vet which one to use.
Does one last longer than the other?
No. Each chew protects for one month, and each pack holds six chews, so both cover six months.
Can I split a chew to adjust the dose?
No. Do not split or share chews between dogs of different weights. Give the chew labeled for your dog's weight.
Is it worth stepping up to a larger size for a growing dog?
Only if the dog's weight already falls in that band. Recheck weight at each refill, since a growing puppy may move up a size.

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More comparisons

  • Simparica Trio Dog Chewable Tablets 2.8-5.5 lb 6 Treatments vs Zoetis Simparica Trio Chewable Tablets for Dogs 88.1-132 lb 6 Month Supply
  • Zoetis Simparica Trio Chewable Tablets for Dogs 88.1-132 lb 6 Month Supply vs Zoetis Simparica Trio Chewable Tablet 11.1-22 lbs 6 pcs
  • Simparica Trio Dog Chewable Tablets 2.8-5.5 lb 6 Treatments vs Simparica Trio For Dogs 88.1-132 lbs (40-60 kg)
  • Zoetis Simparica Trio Chewable Tablet 11.1-22 lbs 6 pcs vs Simparica Trio For Dogs 88.1-132 lbs (40-60 kg)

Buying guides that pick them

  • Best flea, tick and heartworm prevention for dogs