Frontline Plus is a topical spot-on treatment for dogs 5–22 lbs that kills adult fleas, flea eggs and larvae, ticks and chewing lice. Its active ingredients, fipronil and (S)-methoprene, spread through the coat and settle in the sebaceous glands, releasing protection for a full 30 days per application. It becomes waterproof after 24 hours, so baths and swimming don't wash it off. It suits small-dog owners who want a monthly, vet-familiar product that also breaks the flea life cycle; rivals like NexGard and Bravecto are oral chews that last one to three months, while Frontline Plus stays a topical that some owners prefer for dogs that resist pills.
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Owners rate it highly and many have used it for years as their default monthly protection. Praise centers on flea and tick control and the convenience of a topical, while complaints focus on residue, smell and occasional breakthrough fleas.
Frontline Plus for Small Dogs is a liquid topical flea and tick treatment for dogs 5 to 22 lbs and 8 weeks and older. It kills fleas, flea eggs and larvae, so it breaks the flea life cycle, and it also kills ticks and chewing lice. This includes ticks that can transmit Lyme disease.
One application protects for 30 days. The treatment is deposited into the sebaceous glands and redistributes across the coat. It is waterproof after 24 hours, so it stays effective through baths, swimming and rain.
To apply, part the coat between the shoulder blades and put the entire applicator directly on the skin. Repeat every 30 days. Avoid contact with the treated area until it is dry.












