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Frontline
Frontline Plus Flea and Tick Treatment for Dogs

Frontline Plus Flea and Tick Treatment for Dogs

4.2(26,000 ratings)

Best price now

$41.16at WalmartChecked 10 h ago

Compared across 4 stores. Prices are checked against each store and labelled with when.

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Price facts

  • Lowest price today: $41.16 at Walmart (checked Nov 11, 2026).
  • It's up $6.27 from $34.89 a week ago.
  • Checked at 4 stores.

Our take on the Frontline Plus Flea and Tick Treatment for Dogs

Frontline Plus is a monthly topical flea and tick treatment for dogs, applied to one spot between the shoulder blades. Its two active ingredients, fipronil and (S)-methoprene, kill adult fleas and also stop eggs and larvae from developing, which breaks the flea life cycle rather than just clearing live fleas. The formula collects in the dog's oil glands and keeps replenishing onto the skin, and it stays effective after swimming or bathing. It is approved for puppies from 8 weeks old weighing at least 5 pounds. Compared with chewable oral products it is slower to start and leaves a greasy spot for a day or two, but it covers the environment's flea stages and costs less than most prescription chewables. Owners rate it well overall, though some report fleas returning and complain about the applicator and the residue.

Best forDog owners who want a monthly topical rather than an oral chewHouseholds with dogs that swim or get bathed oftenHomes fighting an active flea infestation with eggs and larvaeMulti-dog households treating every pet at once
Pros
  • Kills adult fleas plus eggs and larvae, breaking the flea life cycle
  • Waterproof once dry; bathing and swimming don't require re-application
  • One spot application, no pill to hide in food
  • Approved for puppies from 8 weeks and 5 pounds
  • Works for a full 30 days per dose
Cons
  • Takes longer to start killing fleas than fast-acting oral chewables
  • Leaves an oily patch and a strong chemical smell at the application site
  • Does not repel ticks; ticks must bite before they die
  • Some owners report fleas persisting or returning
  • Dosing is weight-banded, so a growing puppy may need a different size

Frontline Plus Flea and Tick Treatment for Dogs prices at every store

  • WalmartNew

    In stock

    $41.16Checked 10 h ago
    Visit Walmart
  • Feeders Pet SupplyNew

    In stock

    $42.99Checked 10 h ago
    Visit Feeders Pet Supply
  • Coastal Farm & RanchNew

    In stock

    $43.99Checked 10 h ago
    Visit Coastal Farm & Ranch
  • CountryMaxNew

    Availability unknown

    $49.99Checked 10 h ago
    Visit CountryMax

Also available at

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Frontline Plus Flea and Tick Treatment for Dogs price history

$40.98$32.78
Nov 4Nov 11

Lowest price we've seen: $32.78 on Nov 11 at Petco.com; highest $34.89 on Nov 4; $40.98 now. Tracked across 27 stores since Nov 4.

What reviewers say

  • 4.2 / 526,000 ratings

With over 26,000 ratings averaging 4.2 out of 5, most owners say it keeps their dogs flea-free month after month and holds up through swimming and baths. Complaints center on fleas that survive or come back, the greasy residue and smell, and the applicator.

What people mention
  • EffectivenessMixedMany owners say it clears infestations and keeps dogs flea-free, while others report fleas surviving or returning.
  • WaterproofingPraisedOwners say protection holds up through swimming and baths without re-applying.
  • ResidueCriticisedReviewers mention an oily patch and a strong chemical smell at the application site for a day or so.
  • ApplicatorCriticisedSome find the tubes hard to open and hard to empty fully onto the skin.
  • Ease of usePraisedOwners like the single-spot dose compared with getting dogs to take a pill.
  • TicksMixedIt kills ticks that bite, but owners note ticks are not repelled and can still attach.

From Lion Country Supply

  • Kills adult fleas and ticks
  • Destroys flea eggs and larvae and prevents all flea stages from developing
  • Long-lasting formula stored in the pet's oil glands delivers protection for a full 30 days
  • Kills fleas for up to three months and ticks for at least one month
  • Completely waterproof, so the pet can swim and be bathed without re-application
  • Approved for use on puppies 8 weeks and older
Materials
Fipronil 9.8%, (S) Methoprene 8.8%, inert ingredients 81.4%
Care
Waterproof; pet can swim and be bathed without re-application. At least 30 days between applications required.
In the box
Each box contains a 3 month supply

About the Frontline Plus Flea and Tick Treatment for Dogs

Frontline Plus for Dogs is a topical flea and tick treatment. It kills adult fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. It contains fipronil and (S)-methoprene, which work together to break the flea life cycle and guard against further infestations.

The treatment is applied to a single point on the dog. It covers the entire body and deposits in the sebaceous glands, which act as a reservoir that continuously replenishes it on the coat. The formula is waterproof, so it keeps working if the dog gets wet, swims, or is bathed.

One dose each month protects against fleas and ticks for a full 30 days. It can be used on puppies 8 weeks and older that weigh 5 pounds or more. A separate Frontline Plus formula is made for cats and kittens 8 weeks and older that weigh 1.5 pounds or more.

Active ingredients
Fipronil 9.8%, (S)-methoprene 8.8%
Inert ingredients
81.4%
Kills
Adult fleas, flea eggs, flea larvae, chewing lice, ticks
Protection
30 days per dose
Minimum age
8 weeks (puppies)
Minimum weight
5 pounds
Application
Once a month, at least 30 days apart
Waterproof
Yes, no re-application after swimming or bathing
In the box
3 month supply

Specifications

Animal
Cat, Dog

Questions and answers

How does Frontline Plus differ from Frontline Plus for cats?
The dog formula is dosed by the dog's weight and is approved for dogs from 8 weeks and 5 pounds. The cat formula is a separate product with a different dose for cats and kittens from 8 weeks and 1.5 pounds. Never use the dog product on a cat.
Does it still work if my dog swims or gets a bath?
Yes. Once the application site is dry, the formula is waterproof and stored in the oil glands, so swimming and bathing do not require re-application. Avoid bathing the dog for about 48 hours after applying so it absorbs.
How long does one dose last?
One dose protects against fleas and ticks for a full 30 days. The box holds a 3-month supply, so reapply monthly.
Can I use it on a puppy?
It is approved for puppies 8 weeks and older that weigh at least 5 pounds. Match the dose to the puppy's current weight, and check with your vet for very small or frail puppies.
Why are fleas still on my dog after applying it?
Fipronil kills fleas after they jump on, so newly arriving fleas can be seen for a while, and eggs and larvae in the home take weeks to clear. Treat every pet in the house and vacuum regularly, and see a vet if fleas persist after a few months.
Is it safe around other pets in the house?
Keep treated dogs from licking each other's application sites until dry, and treat every dog and cat in the home with the product made for its species. Do not apply the dog formula to cats.
Where is the Frontline Plus Flea and Tick Treatment for Dogs cheapest?
At Walmart, for $41.16, as of our latest check.
What do buyers say about the Frontline Plus Flea and Tick Treatment for Dogs?
Rated 4.2 out of 5 from 26,000 ratings.
Where can I buy the Frontline Plus Flea and Tick Treatment for Dogs?
25 stores we checked sell it, including Walmart, Coastal Farm & Ranch, Feeders Pet Supply, CountryMax, Tractor Supply Co.

Stores we've priced the Frontline Plus Flea and Tick Treatment for Dogs at

  • Chewy.com deals and prices
  • Coastal Farm & Ranch deals and prices
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  • Walmart deals and prices
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