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Simparica Trio is a monthly oral chew that combines sarolaner, moxidectin and pyrantel in one dose. It protects dogs 8 weeks and older against fleas, ticks, heartworm, roundworms and hookworms, and kills fleas fast, starting within 4 hours and reaching full efficacy by 8 hours. It is approved to kill six tick species and to prevent Lyme disease from Borrelia burgdorferi. It suits owners who want one liver-flavored chew instead of separate flea, tick and heartworm products, and it competes with other all-in-one chewables such as NexGard Spectra and Credelio Plus.
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Owners and reviewers generally rate Simparica Trio highly for convenience and fast flea kill. Many report their dogs take the liver chew without fuss and that fleas and ticks disappear quickly. A minority mention vomiting or loose stools after dosing and some dogs refusing the chew.
Simparica Trio is a once-monthly liver-flavored chew for dogs 8 weeks and older. This size is for dogs weighing 44.1–88 lbs. It combines three active ingredients: sarolaner, moxidectin and pyrantel embonate.
One chew protects against fleas, ticks, heartworm, roundworms and hookworms. It begins killing fleas within 4 hours and reaches 100% efficacy by 8 hours. It kills six tick species and prevents Lyme disease caused by Borrelia burgdorferi.
The chew treats and controls adult and immature roundworm and hookworm infections. Given monthly, it prevents heartworm disease. It also helps prevent flea-tapeworm infection by killing the fleas that carry it.
