What does Simparica Trio protect against?

It protects against fleas, six types of ticks, heartworm disease, roundworms, hookworms and flea tapeworms. One chew is given monthly.

How fast does it kill fleas?

It starts killing fleas within 4 hours and reaches 100% effectiveness within 8 hours in studies. It also kills fleas before they can lay eggs.

Yes. It is approved for puppies from 8 weeks of age and at least 2.8 lbs. Use the weight band that matches your puppy's current weight.

Does my dog need a prescription?

Yes. Simparica Trio is a prescription product, so your vet must authorize it. Ask your vet whether it suits your dog's health and weight.

Give one chew by mouth once a month, with or without food. Most dogs take the liver-flavored chew voluntarily.

What if my dog vomits after taking it?

Contact your vet, especially if vomiting happens soon after dosing, since the dose may not have been absorbed. Your vet can advise whether to redose.

Where is the Simparica Trio for Dogs 11.1-22 lbs (5-10 kg) cheapest?

At Allivet Pet Pharmacy, for $234.77, as of our latest check.

What do buyers say about the Simparica Trio for Dogs 11.1-22 lbs (5-10 kg)?

Rated 4.8 out of 5 from 23 ratings. Buyers like: One pill once a month covers several health hazards; No fleas or ticks seen on dogs for years; No side effects reported.

Where can I buy the Simparica Trio for Dogs 11.1-22 lbs (5-10 kg)?

6 stores we checked sell it, including Allivet Pet Pharmacy, Amazon, 79Pets.com, Tractor Supply Company, Performance Vet Supply.

Simparica Trio for Dogs 11.1-22 lbs Price History: Lowest $234.77

What reviewers say

4.8 / 523 ratings

Owners rate it 4.8 out of 5 and most praise the single monthly chew and years of flea- and tick-free dogs. Many say their dogs take it without fuss and report no side effects. A few mention mild stomach upset after dosing.

What people mention

ConveniencePraisedOwners like replacing several products with one monthly chew.
Flea and tick controlPraisedBuyers report no fleas or ticks on their dogs for years.
PalatabilityPraisedMost dogs take the liver-flavored chew without a fight.
Side effectsMixedA few owners report mild stomach upset after dosing.
Vet recommendationPraisedBuyers say their vet recommended it and trust the combination.

From Allivet Pet Pharmacy

Monthly liver-flavored chew protects against heartworms, ticks, fleas, flea tapeworms, roundworms and hookworms
#1 vet-prescribed combo preventative
First FDA-approved combination preventative to kill six types of ticks, including the deer tick that may carry Lyme infections
Starts killing fleas within 4 hours with 100% effectiveness in 8 hours; kills fleas before they lay eggs
Approved for puppies as young as 8 weeks old and weighing at least 2.8 lbs
Can be given with or without food; 9 out of 10 dogs voluntarily consumed it in a study

Sizes: 2.8-5.5 lbs, 5.5-11 lbs, 11-22 lbs, 22-44 lbs, 44-88 lbs, 88-132 lbs
Materials: Active ingredients: Sarolaner, Moxidectin, Pyrantel
Sizing: Dosed by body weight; this 11.1-22 lbs (5-10 kg) size is for dogs in that weight range. Give one chew monthly; if a dose is missed, give immediately and resume
Guarantee: 100% satisfaction guarantee on protection; call Zoetis' medical support team at 1-888-ZOETIS1 if protection seems insufficient.
Returns: Prescription drugs cannot be returned due to federal and state laws.
Shipping: Usually shipped in 1-3 business days; free 1-3 day standard shipping on qualifying orders (cold-ship items and Hawaii/Alaska excluded); prescription orders may
Packs: Sold as 1 Month, 3 Month, 6 Month or 12 Month Supply
In the box: Simparica Trio chewable tablets for the selected supply length (1, 3, 6 or 12 months)

Size chart

Body Weight	Sarolaner per Tablet (mg	Moxidectin per Tablet (m	Pyrantel per Tablet (mg)	Number of Tablets Admini
2.8 to 5.5 lbs	3.0	0.06	12.5	1
5.5 to 11 lbs	6.0	0.12	25	1
11-22 lbs	12	0.24	50	1
22-44 lbs	24	0.48	100	1
44-88 lbs	48	0.96	200	1
88-132 lbs	72	1.44	300	1

About the Simparica Trio for Dogs 11.1-22 lbs (5-10 kg)

Simparica Trio is a once-monthly chewable tablet for dogs. It protects against heartworm disease, ticks, fleas, flea tapeworms, roundworms, and hookworms. The chew is liver flavored and can be given with or without food. This size is for dogs weighing 11.1-22 lbs (5-10 kg).

It kills fleas before they can lay eggs. In studies, it starts killing fleas within 4 hours and reaches 100% effectiveness in 8 hours. It is FDA-approved to kill six types of ticks, including the deer tick that may carry Lyme infections. It kills 98.9% of pre-existing paralysis ticks within 24 hours.

Dosing is by body weight, with one chew given monthly. It is approved for puppies as young as 8 weeks old that weigh at least 2.8 lbs.

Active ingredients: Sarolaner, moxidectin, and pyrantel
Protects against: Heartworm disease, ticks, fleas, flea tapeworms, roundworms, hookworms
Dog weight: 11.1-22 lbs (5-10 kg)
Minimum age: 8 weeks, and at least 2.8 lbs
Dosing: One chew per month
Form: Oral chewable tablet
Flavor: Liver
Tablet: Reddish brown, pentagon shaped with rounded edges
Flea kill speed: Starts within 4 hours, 100% effective in 8 hours
Flea protection: 35 days
Paralysis ticks: 98.9% of pre-existing paralysis ticks killed within 24 hours
Screwworm use: Authorized under an FDA Emergency Use Authorization to treat New World screwworm larvae (myiasis) in dogs and puppies, for the duration of the emergency declaration. Not approved for this use.