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Simparica Trio is a once-monthly chewable that combines flea, tick, heartworm and intestinal worm protection in one tablet. It is the first FDA-approved combo product that kills six tick species, including the deer tick linked to Lyme disease, and it starts killing fleas within 4 hours. Vets prescribe it widely and most dogs take the liver-flavored chew on their own. It suits owners who want one monthly dose instead of separate flea, tick and heartworm products, though it is a prescription item and not for dogs under 8 weeks or below the labeled weight.
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Lowest price we've seen: $38.90 on Nov 15 at Tractor Supply Co; $39.47 now. Tracked across 14 stores since Nov 15.
Owners rate it highly and most say their dogs eat the chew without fuss. Complaints center on stomach upset in some dogs and the need for a vet prescription.
| Weight (lb.) | Sarolaner per Tablet (mg | Moxidectin per Tablet (m | Pyrantel per Tablet (mg) | Number of Tablets Admini |
|---|---|---|---|---|
| 2.8 to 5.5 lb. | 3.0 | 0.06 | 12.5 | 1 |
| 5.5 to 11 lb. | 6.0 | 0.12 | 25 | |
| 11-22 lb. | 12 | 0.24 | 50 | |
| 22-44 lb. | 24 | 0.48 | 100 | |
| 44-88 lb. | 48 | 0.96 | 200 | |
| 88-132 lb. | 72 | 1.44 | 300 |
Simparica Trio is a once-monthly, liver-flavored chewable tablet for dogs. It protects against heartworm disease, ticks, fleas, flea tapeworms, roundworms and hookworms. This package is the 3-month supply for dogs weighing 2.8 to 5.5 lb.
It kills fleas before they can lay eggs. In studies, it started killing fleas within 4 hours and reached 100% effectiveness in 8 hours. It is the first combination preventative FDA-approved to kill six types of ticks, including the deer tick that may carry Lyme infections.
It can be given with or without food. In a study, 9 out of 10 dogs took it voluntarily. It is approved for puppies as young as eight weeks old who weigh at least the labeled minimum for the size. Dosing is based on the dog's weight.
